Find Supratonin manufacturers, exporters & distributors on PharmaCompass

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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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USDMF

US DMFs Filed

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CEP/COS

CEP/COS Certifications

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EU WC

EU WC

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KDMF

KDMF

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NDC API

NDC API

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VMF

NDC API

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Listed Suppliers

Other Suppliers

API REF. PRICE (USD/KG)

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$ 0

MARKET PLACE

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API

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FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

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FDF Dossiers

FDF Dossiers

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FDA Orange Book

FDA (Orange Book)

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Europe

Europe

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Canada

Canada

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Australia

Australia

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South Africa

South Africa

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Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

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EDQM

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USP

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JP

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Others

PATENTS & EXCLUSIVITIES

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US Patents

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Data Compilation #PharmaFlow

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Stock Recap #PipelineProspector

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GLOBAL SALES INFORMATION

US Medicaid

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Annual Reports

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0RELATED EXCIPIENT COMPANIES

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Chemistry

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Also known as: 30578-37-1, Amezinium methylsulfate, Amezinium methyl sulfate, Supratonin, Regulton, Amezinium (methylsulfate)
Molecular Formula
C12H15N3O5S
Molecular Weight
313.33  g/mol
InChI Key
ZEASXVYVFFXULL-UHFFFAOYSA-N
FDA UNII
03NR868ICX

Supratonin
1 2D Structure

Supratonin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
6-methoxy-1-phenylpyridazin-1-ium-4-amine;methyl sulfate
2.1.2 InChI
InChI=1S/C11H11N3O.CH4O4S/c1-15-11-7-9(12)8-13-14(11)10-5-3-2-4-6-10;1-5-6(2,3)4/h2-8,12H,1H3;1H3,(H,2,3,4)
2.1.3 InChI Key
ZEASXVYVFFXULL-UHFFFAOYSA-N
2.1.4 Canonical SMILES
COC1=[N+](N=CC(=C1)N)C2=CC=CC=C2.COS(=O)(=O)[O-]
2.2 Other Identifiers
2.2.1 UNII
03NR868ICX
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 4-amino-6-methoxy-1-phenylpyridazinium Methylsulfate

2. Amezinium

3. Amezinium Chloride

4. Amezinium Methyl Sulfate

5. Amezinium Metisulfate

6. Amezinium Triflouoacetate Salt (1:1)

7. Lu 1631

8. Regulton

9. Supratonin

2.3.2 Depositor-Supplied Synonyms

1. 30578-37-1

2. Amezinium Methylsulfate

3. Amezinium Methyl Sulfate

4. Supratonin

5. Regulton

6. Amezinium (methylsulfate)

7. Amezinii Metilsulfas

8. Risumic

9. Metilsulfate D'amezinium

10. Metilsulfato De Amezinio

11. 4-amino-6-methoxy-1-phenylpyridazin-1-ium Methyl Sulfate

12. Lu 1631

13. Amezinium Metilsulphate

14. 4-amino-6-methoxy-1-phenylpyridazinium Methyl Sulfate

15. Lu-1631

16. 03nr868icx

17. Pyridazinium, 4-amino-6-methoxy-1-phenyl-, Methyl Sulfate

18. Amezinium Metilsulfate;lu-1631

19. Amezinium Metilsulfate (jan)

20. 6-methoxy-1-phenylpyridazin-1-ium-4-amine;methyl Sulfate

21. Amezinium Metilsulfate [jan]

22. Ameziniummetilsulfat

23. Ameziniummetilsulfat [german]

24. Amezinio Metilsulfato

25. Amezinio Metilsulfato [spanish]

26. Amezinii Metilsulfas [inn-latin]

27. Amezinium Metilsulfate [inn:jan]

28. Einecs 250-248-0

29. Metilsulfate D'amezinium [inn-french]

30. Metilsulfato De Amezinio [inn-spanish]

31. Unii-03nr868icx

32. Amezinin

33. Dialead

34. Epinotec

35. Parcekion

36. Risumelic

37. Rizmylate

38. Rizumile

39. Solmfurin

40. Tenfortan

41. Acomic

42. Amegyl

43. Metroc

44. Upfree

45. Ofvit

46. Risumic (tn)

47. 4-amino-6-methoxy-1-phenylpyridazinium-methylsulfat [german]

48. Schembl309661

49. 4-amino-6-methoxy-1-phenylpyridazinium-methylsulfat

50. Chembl2106667

51. Chebi:31201

52. 6-methoxy-1-phenylpyridazin-1-ium-4-amine,methyl Sulfate

53. Dtxsid00184657

54. Hy-a0275

55. Amezinium Metilsulfate [inn]

56. Mfcd00865972

57. Amezinium Methyl Sulfate [mi]

58. Amezinium Metilsulfate [mart.]

59. Amezinium Metilsulfate [who-dd]

60. Cs-5554

61. Db13330

62. S11901

63. Ds-14012

64. Ft-0703448

65. D01304

66. A911631

67. 4-amino-6-methoxy-1-phenylpyridaziniummethylsulfate

68. 4-amino-6-methoxy-1-phenyl-pyridazinium Methyl Sulfate

69. 6-methoxy-1-phenylpyridazin-1-ium-4-amine Methylsulfate

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 313.33 g/mol
Molecular Formula C12H15N3O5S
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count2
Exact Mass313.07324176 g/mol
Monoisotopic Mass313.07324176 g/mol
Topological Polar Surface Area127 Ų
Heavy Atom Count21
Formal Charge0
Complexity285
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Monoamine Oxidase Inhibitors

A chemically heterogeneous group of drugs that have in common the ability to block oxidative deamination of naturally occurring monoamines. (From Gilman, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p414) (See all compounds classified as Monoamine Oxidase Inhibitors.)


Sympathomimetics

Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. (See all compounds classified as Sympathomimetics.)


4.2 ATC Code

C - Cardiovascular system

C01 - Cardiac therapy

C01C - Cardiac stimulants excl. cardiac glycosides

C01CA - Adrenergic and dopaminergic agents

C01CA25 - Amezinium metilsulfate


ABOUT THIS PAGE

Supratonin Manufacturers

A Supratonin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Supratonin, including repackagers and relabelers. The FDA regulates Supratonin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Supratonin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Supratonin Suppliers

A Supratonin supplier is an individual or a company that provides Supratonin active pharmaceutical ingredient (API) or Supratonin finished formulations upon request. The Supratonin suppliers may include Supratonin API manufacturers, exporters, distributors and traders.

click here to find a list of Supratonin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Supratonin JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Supratonin Drug Master File in Japan (Supratonin JDMF) empowers Supratonin API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Supratonin JDMF during the approval evaluation for pharmaceutical products. At the time of Supratonin JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Supratonin suppliers with JDMF on PharmaCompass.

Supratonin GMP

Supratonin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Supratonin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Supratonin GMP manufacturer or Supratonin GMP API supplier for your needs.

Supratonin CoA

A Supratonin CoA (Certificate of Analysis) is a formal document that attests to Supratonin's compliance with Supratonin specifications and serves as a tool for batch-level quality control.

Supratonin CoA mostly includes findings from lab analyses of a specific batch. For each Supratonin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Supratonin may be tested according to a variety of international standards, such as European Pharmacopoeia (Supratonin EP), Supratonin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Supratonin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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