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Chemistry

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Also known as: Suril, 53813-83-5, Celexane, Rp 31264, Rp-31264, Lnc9g689vr
Molecular Formula
C20H20ClN5O3S2
Molecular Weight
478.0  g/mol
InChI Key
RMXOUBDDDQUBKD-UHFFFAOYSA-N
FDA UNII
LNC9G689VR

Suriclone
1 2D Structure

Suriclone

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[6-(7-chloro-1,8-naphthyridin-2-yl)-5-oxo-3,7-dihydro-2H-[1,4]dithiino[2,3-c]pyrrol-7-yl] 4-methylpiperazine-1-carboxylate
2.1.2 InChI
InChI=1S/C20H20ClN5O3S2/c1-24-6-8-25(9-7-24)20(28)29-19-16-15(30-10-11-31-16)18(27)26(19)14-5-3-12-2-4-13(21)22-17(12)23-14/h2-5,19H,6-11H2,1H3
2.1.3 InChI Key
RMXOUBDDDQUBKD-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CN1CCN(CC1)C(=O)OC2C3=C(C(=O)N2C4=NC5=C(C=C4)C=CC(=N5)Cl)SCCS3
2.2 Other Identifiers
2.2.1 UNII
LNC9G689VR
2.3 Synonyms
2.3.1 MeSH Synonyms

1. (8-(7-chloro(1,8)naphthyridin-2-yl)-7-oxo-2,5-dithia-8-azabicyclo(4.3.0)non-10-en-9-yl) 4-methylpiperazine-1-carboxylate

2. 6-(7-chloro-1,8-naphthyridin-2-yl)-2,3,6,7-tetrahydro-7-oxo-5h-(1,4)dithiino(2,3-c)pyrrol-5-yl-4-methylpiperazine-1-carboxylate

3. Rp 31264

4. Rp-3124

5. Rp-31264

2.3.2 Depositor-Supplied Synonyms

1. Suril

2. 53813-83-5

3. Celexane

4. Rp 31264

5. Rp-31264

6. Lnc9g689vr

7. Celexane; Rp 31264; Suriclone

8. Suriclonum

9. Suriclon

10. Suriclona

11. Suriclon [inn-french]

12. Suriclonum [inn-latin]

13. Suriclona [inn-spanish]

14. Einecs 258-794-1

15. 6-(7-chloro-1,8-naphthyridin-2-yl)-7-oxo-2,3,6,7-tetrahydro-5h-[1,4]dithiino[2,3-c]pyrrol-5-yl 4-methylpiperazine-1-carboxylate

16. Suriclone [inn:ban]

17. Unii-lnc9g689vr

18. Suriclone [inn]

19. Suriclone [mi]

20. Suriclone [mart.]

21. (r,s)-6-(7-chlor-1,8-naphthyridin-2-yl)-3,5,6,7-tetrahydro-5-oxo-2h-(1,4)dithixino(2,3-c)pyrrol-7-yl-4-methyl-1-piperazinylcarboxylat

22. [6-(7-chloro-1,8-naphthyridin-2-yl)-5-oxo-3,7-dihydro-2h-[1,4]dithiino[2,3-c]pyrrol-7-yl] 4-methylpiperazine-1-carboxylate

23. Schembl114688

24. Chembl2105561

25. Dtxsid20866362

26. 31264-rp

27. 4-methyl-1-piperazinecarboxylic Acid Ester With (+-)-6-(7-chloro-1,8-naphthyridin-2-yl)-2,3,6,7-tetrahydro-7-hydroxy-5h-p-dithiino(2,3-c)pyrrol-5-one

28. Q7646277

29. 1-piperazinecarboxylic Acid, 4-methyl-, 6-(7-chloro-1,8-naphthyridin-2-yl)-2,3,6,7-tetrahydro-7-oxo-5h-1,4-dithiino(2,3-c)pyrrol-5-yl Ester

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 478.0 g/mol
Molecular Formula C20H20ClN5O3S2
XLogP32.8
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count8
Rotatable Bond Count3
Exact Mass477.0696096 g/mol
Monoisotopic Mass477.0696096 g/mol
Topological Polar Surface Area130 Ų
Heavy Atom Count31
Formal Charge0
Complexity763
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Anxiety Agents

Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here. (See all compounds classified as Anti-Anxiety Agents.)


API SUPPLIERS

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ABOUT THIS PAGE

Suriclone Manufacturers

A Suriclone manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Suriclone, including repackagers and relabelers. The FDA regulates Suriclone manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Suriclone API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Suriclone Suppliers

A Suriclone supplier is an individual or a company that provides Suriclone active pharmaceutical ingredient (API) or Suriclone finished formulations upon request. The Suriclone suppliers may include Suriclone API manufacturers, exporters, distributors and traders.

click here to find a list of Suriclone suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Suriclone USDMF

A Suriclone DMF (Drug Master File) is a document detailing the whole manufacturing process of Suriclone active pharmaceutical ingredient (API) in detail. Different forms of Suriclone DMFs exist exist since differing nations have different regulations, such as Suriclone USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Suriclone DMF submitted to regulatory agencies in the US is known as a USDMF. Suriclone USDMF includes data on Suriclone's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Suriclone USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Suriclone suppliers with USDMF on PharmaCompass.

Suriclone GMP

Suriclone Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Suriclone GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Suriclone GMP manufacturer or Suriclone GMP API supplier for your needs.

Suriclone CoA

A Suriclone CoA (Certificate of Analysis) is a formal document that attests to Suriclone's compliance with Suriclone specifications and serves as a tool for batch-level quality control.

Suriclone CoA mostly includes findings from lab analyses of a specific batch. For each Suriclone CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Suriclone may be tested according to a variety of international standards, such as European Pharmacopoeia (Suriclone EP), Suriclone JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Suriclone USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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