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Suxamethonium Chloride Dihydrate

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Also known as: 6101-15-1, Suxamethonium chloride dihydrate, Choline chloride succinate, Suxamethonium chloride, Suxamethonium chloride hydrate, Succinyldicholine dichloride

Molecular Formula

C₁₄H₃₄Cl₂N₂O₆

Molecular Weight

397.3 g/mol

InChI Key

FFSBEIRFVXGRPR-UHFFFAOYSA-L

FDA UNII

8L0S1G435E

A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxant, acting in about 30 seconds and with a duration of effect averaging three to five minutes. Succinylcholine is used in surgical, anesthetic, and other procedures in which a brief period of muscle relaxation is called for.

1 2D Structure

Suxamethonium Chloride Dihydrate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

trimethyl-[2-[4-oxo-4-[2-(trimethylazaniumyl)ethoxy]butanoyl]oxyethyl]azanium;dichloride;dihydrate

2.1.2 InChI

InChI=1S/C14H30N2O4.2ClH.2H2O/c1-15(2,3)9-11-19-13(17)7-8-14(18)20-12-10-16(4,5)6;;;;/h7-12H2,1-6H3;2*1H;2*1H2/q+2;;;;/p-2

2.1.3 InChI Key

FFSBEIRFVXGRPR-UHFFFAOYSA-L

2.1.4 Canonical SMILES

C[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C.O.O.[Cl-].[Cl-]

2.2 Other Identifiers

2.2.1 UNII

8L0S1G435E

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Anectine

2. Bromide, Suxamethonium

3. Celocurine

4. Dibromide, Succinylcholine

5. Dichloride, Succinylcholine

6. Dicholine Succinate

7. Diiodide, Succinylcholine

8. Diperchlorate, Succinylcholine

9. Ditilin

10. Listenon

11. Lysthenon

12. Myorelaxin

13. Quelicin

14. Succicuran

15. Succinate, Dicholine

16. Succinylcholine

17. Succinylcholine Chloride

18. Succinylcholine Dibromide

19. Succinylcholine Dichloride

20. Succinylcholine Dichloride, Di H2o

21. Succinylcholine Dichloride, Di-h2o

22. Succinylcholine Diiodide

23. Succinylcholine Diperchlorate

24. Succinylcholine Iodide

25. Succinyldicholine

26. Suxamethonium

27. Suxamethonium Bromide

28. Suxamethonium Chloride

2.3.2 Depositor-Supplied Synonyms

1. 6101-15-1

2. Suxamethonium Chloride Dihydrate

3. Choline Chloride Succinate

4. Suxamethonium Chloride

5. Suxamethonium Chloride Hydrate

6. Succinyldicholine Dichloride

7. Suxamethonium Chloride Hydrate [jan]

8. 8l0s1g435e

9. 6101-15-1 (chloride Dihydrate)

10. Ethanaminium, 2,2'-((1,4-dioxo-1,4-butanediyl)bis(oxy))bis(n,n,n-trimethyl-), Dichloride, Dihydrate

11. 2,2'-(succinylbis(oxy))bis(n,n,n-trimethylethan-1-aminium) Chloride Dihydrate

12. Unii-8l0s1g435e

13. Mfcd00150564

14. Succin (tn)

15. Suxamethonium Chloride 2h2o

16. Succinylcholine Chloride 2h2o

17. Succinylbischolinchloriddihydrat

18. Chebi:61225

19. Dtxsid50976488

20. Hms3887k13

21. Succinylcholine Dichloride Dihydrate

22. Succinylcholine (chloride Dihydrate)

23. S4121

24. Succinyldicholine Dichloride Dihydrate

25. Akos024462531

26. Ccg-268618

27. Suxamethonium Chloride [who-ip]

28. Suxamethonium Chloride Hydrate (jp17)

29. S10403

30. Succinylcholine Chloride [who-ip]

31. Ac-33148

32. As-13333

33. Trimethyl-[2-[4-oxo-4-[2-(trimethylazaniumyl)ethoxy]butanoyl]oxyethyl]azanium;dichloride;dihydrate

34. Db-053765

35. B1595

36. Ft-0635981

37. Suxamethonii Chloridum [who-ip Latin]

38. D02275

39. Suxamethonium Chloride Dihydrate [who-dd]

40. A837139

41. Q-201774

42. Q27130900

43. Succinylcholine Chloride Dihydrate, 98.0-102.0%, Solid

44. Suxamethonium Chloride, European Pharmacopoeia (ep) Reference Standard

45. 2,2'-succinyldioxybis(ethyltrimethylammonium) Dichloride, Dihydrate [who-ip]

46. Succinylcholine Chloride, United States Pharmacopeia (usp) Reference Standard

47. 2,2'-[(1,4-dioxobutane-1,4-diyl)bis(oxy)]bis(n,n,n-trimethylethanaminium) Chloride--water (1/2)

48. 2-[1,4-dioxo-4-[2-(trimethylammonio)ethoxy]butoxy]ethyl-trimethylammonium Dichloride Dihydrate

49. Succin Succin (tn) Suxamethonium Chloride Succinylcholine Chloride Suxamethonium Chloride (jp15) Suxamethonium Chloride Dihydrate Cid656867 D02275 (2-hydroxyethyl)trimethylammonium Chloride Succinate 6101-15-1 71-27-2

50. Trimethyl-[2-[4-oxidanylidene-4-[2-(trimethylazaniumyl)ethoxy]butanoyl]oxyethyl]azanium Dichloride Dihydrate

2.4 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₁₄H₃₄Cl₂N₂O₆
Molecular Weight	397.3 g/mol
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	11
Exact Mass	396.1793922 g/mol
Monoisotopic Mass	396.1793922 g/mol
Topological Polar Surface Area	54.6 Å²
Heavy Atom Count	24
Formal Charge	0
Complexity	284
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	5

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Neuromuscular Depolarizing Agents

Drugs that interrupt transmission at the skeletal neuromuscular junction by causing sustained depolarization of the motor end plate. These agents are primarily used as adjuvants in surgical anesthesia to cause skeletal muscle relaxation. (See all compounds classified as Neuromuscular Depolarizing Agents.)

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Suxamethonium Chloride Dihydrate Manufacturers

A Suxamethonium Chloride Dihydrate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Suxamethonium Chloride Dihydrate, including repackagers and relabelers. The FDA regulates Suxamethonium Chloride Dihydrate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Suxamethonium Chloride Dihydrate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Suxamethonium Chloride Dihydrate Suppliers

A Suxamethonium Chloride Dihydrate supplier is an individual or a company that provides Suxamethonium Chloride Dihydrate active pharmaceutical ingredient (API) or Suxamethonium Chloride Dihydrate finished formulations upon request. The Suxamethonium Chloride Dihydrate suppliers may include Suxamethonium Chloride Dihydrate API manufacturers, exporters, distributors and traders.

Suxamethonium Chloride Dihydrate GMP

Suxamethonium Chloride Dihydrate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Suxamethonium Chloride Dihydrate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Suxamethonium Chloride Dihydrate GMP manufacturer or Suxamethonium Chloride Dihydrate GMP API supplier for your needs.

Suxamethonium Chloride Dihydrate CoA

A Suxamethonium Chloride Dihydrate CoA (Certificate of Analysis) is a formal document that attests to Suxamethonium Chloride Dihydrate's compliance with Suxamethonium Chloride Dihydrate specifications and serves as a tool for batch-level quality control.

Suxamethonium Chloride Dihydrate CoA mostly includes findings from lab analyses of a specific batch. For each Suxamethonium Chloride Dihydrate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Suxamethonium Chloride Dihydrate may be tested according to a variety of international standards, such as European Pharmacopoeia (Suxamethonium Chloride Dihydrate EP), Suxamethonium Chloride Dihydrate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Suxamethonium Chloride Dihydrate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.