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Chemistry

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Also known as: Tabersonin, 4429-63-4, (-)-tabersonine, Mn955k48nb, Chebi:16776, Aspidospermidine-3-carboxylic acid, 2,3,6,7-tetradehydro-, methyl ester, (5alpha,12beta,19alpha)-
Molecular Formula
C21H24N2O2
Molecular Weight
336.4  g/mol
InChI Key
FNGGIPWAZSFKCN-ACRUOGEOSA-N
FDA UNII
MN955K48NB

Tabersonine
tabersonine is a natural product found in Voacanga schweinfurthii, Tabernaemontana citrifolia, and other organisms with data available.
1 2D Structure

Tabersonine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
methyl (1R,12R,19S)-12-ethyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,9,13-pentaene-10-carboxylate
2.1.2 InChI
InChI=1S/C21H24N2O2/c1-3-20-9-6-11-23-12-10-21(19(20)23)15-7-4-5-8-16(15)22-17(21)14(13-20)18(24)25-2/h4-9,19,22H,3,10-13H2,1-2H3/t19-,20-,21-/m0/s1
2.1.3 InChI Key
FNGGIPWAZSFKCN-ACRUOGEOSA-N
2.1.4 Canonical SMILES
CCC12CC(=C3C4(C1N(CC4)CC=C2)C5=CC=CC=C5N3)C(=O)OC
2.1.5 Isomeric SMILES
CC[C@]12CC(=C3[C@@]4([C@H]1N(CC4)CC=C2)C5=CC=CC=C5N3)C(=O)OC
2.2 Other Identifiers
2.2.1 UNII
MN955K48NB
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Tabersonine Monoacetate

2.3.2 Depositor-Supplied Synonyms

1. Tabersonin

2. 4429-63-4

3. (-)-tabersonine

4. Mn955k48nb

5. Chebi:16776

6. Aspidospermidine-3-carboxylic Acid, 2,3,6,7-tetradehydro-, Methyl Ester, (5alpha,12beta,19alpha)-

7. (5alpha,12beta,19alpha)-2,3,6,7-tetradehydroaspidospermidine-3-carboxylic Acid, Methyl Ester

8. Methyl (5alpha,12beta,19alpha)-2,3,6,7-tetradehydroaspidospermidine-3-carboxylate

9. Methyl 2,3,6,7-tetradehydro-5alpha,12beta,19alpha-aspidospermidine-3-carboxylate

10. Einecs 224-615-0

11. Brn 0050163

12. Devil's Claw Extract

13. Unii-mn955k48nb

14. 4-25-00-00997 (beilstein Handbook Reference)

15. Schembl829379

16. Amy596

17. Chembl2011511

18. Tabersonine, >=95% (hplc)

19. Dtxsid30196102

20. Hms3887m03

21. Hy-n1431

22. Mfcd28140545

23. Nsc815334

24. S9427

25. Zinc56871302

26. Akos015896776

27. Ccg-267873

28. Nsc-815334

29. 3a-ethyl-3a,4,6,11,12,13a-hexahydro-1h-indolizino[8,1-cd]carbazole-5-carboxylic Acid Methyl Ester

30. Ac-26458

31. Aspidospermidine-3-carboxylic Acid, 2,3,6,7-tetradehydro-, Methyl Ester, (5.alpha.,12.beta.,19.alpha.)-

32. Aspidospermidine-3-carboxylic Acid, 2,3,6,7-tetrahydro-, Methyl Ester, (5-alpha,12-beta,19-alpha)-

33. Cs-0016859

34. C09244

35. Q21099578

36. 1h-indolizino(8,1-cd)carbazole-5-carboxylic Acid, 3a-ethyl-3a,4,6,11,12,13a-hexahydro-, Methyl Ester

37. Aspidospermidine-3-carboxylic Acid, 2,3,6,7-tetradehydro-, Methyl Ester, (5.alpha.,12r,19.alpha.)-

38. Methyl (1r,12r,19s)-12-ethyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,9,13-pentaene-10-carboxylate

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 336.4 g/mol
Molecular Formula C21H24N2O2
XLogP33.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass336.183778013 g/mol
Monoisotopic Mass336.183778013 g/mol
Topological Polar Surface Area41.6 Ų
Heavy Atom Count25
Formal Charge0
Complexity669
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Tabersonine Manufacturers

A Tabersonine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Tabersonine, including repackagers and relabelers. The FDA regulates Tabersonine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Tabersonine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Tabersonine manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Tabersonine Suppliers

A Tabersonine supplier is an individual or a company that provides Tabersonine active pharmaceutical ingredient (API) or Tabersonine finished formulations upon request. The Tabersonine suppliers may include Tabersonine API manufacturers, exporters, distributors and traders.

click here to find a list of Tabersonine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Tabersonine GMP

Tabersonine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Tabersonine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Tabersonine GMP manufacturer or Tabersonine GMP API supplier for your needs.

Tabersonine CoA

A Tabersonine CoA (Certificate of Analysis) is a formal document that attests to Tabersonine's compliance with Tabersonine specifications and serves as a tool for batch-level quality control.

Tabersonine CoA mostly includes findings from lab analyses of a specific batch. For each Tabersonine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Tabersonine may be tested according to a variety of international standards, such as European Pharmacopoeia (Tabersonine EP), Tabersonine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Tabersonine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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