Euroapi Company Header Euroapi Company Header

X

Find Tacalcitol manufacturers, exporters & distributors on PharmaCompass

PharmaCompass
API SUPPLIERS
API Suppliers

API Suppliers

US DMFs Filed

US DMFs Filed

0

CEP/COS Certifications

CEP/COS Certifications

JDMFs Filed

JDMFs Filed

EU WC

EU WC

0

Listed Suppliers

Listed Suppliers

API REF. PRICE (USD / KG)

0

INTERMEDIATES

0

DOSSIERS // FDF
USA (Orange Book)

USA (Orange Book)

0

Europe

Europe

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

0

Uploaded Dossiers

Uploaded Dossiers

0

GLOBAL SALES (USD Million)

U.S. Medicaid

0

Annual Reports

0

EXCIPIENTS

0

PATENTS & EXCLUSIVITIES

USFDA Orange Book Patents

0

USFDA Exclusivities

0

DIGITAL CONTENT

Blog #PharmaFlow

0

News

0

REF STANDARD

EDQM

0

USP

0

JP

Other Listed Suppliers

0

SERVICES

0

Tacalcitol
Also known as: 57333-96-7, Bonalfa, Curatoderm, Tacalcitolum, Tv-02h, Tv-02
Molecular Formula
C27H44O3
Molecular Weight
416.6  g/mol
InChI Key
BJYLYJCXYAMOFT-RSFVBTMBSA-N
FDA UNII
C2W72OJ5ZU

1 2D Structure

Tacalcitol

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R,5R)-5-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
2.1.2 InChI
InChI=1S/C27H44O3/c1-17(2)25(29)13-8-18(3)23-11-12-24-20(7-6-14-27(23,24)5)9-10-21-15-22(28)16-26(30)19(21)4/h9-10,17-18,22-26,28-30H,4,6-8,11-16H2,1-3,5H3/b20-9+,21-10-/t18-,22-,23-,24+,25-,26+,27-/m1/s1
2.1.3 InChI Key
BJYLYJCXYAMOFT-RSFVBTMBSA-N
2.1.4 Canonical SMILES
CC(C)C(CCC(C)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C)O
2.1.5 Isomeric SMILES
C[C@H](CC[C@H](C(C)C)O)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](C[C@@H](C3=C)O)O)C
2.2 Other Identifiers
2.2.1 UNII
C2W72OJ5ZU
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 1 Alpha,24-dihydroxycholecalciferol

2. 1 Alpha,24-dihydroxyvitamin D3

3. 1 Alpha,24-dihydroxyvitamin D3, (1alpha,3beta,5z,7e,24r)-isomer

4. 1 Alpha,24-dihydroxyvitamin D3, (1alpha,3beta,5z,7e,24s)-isomer

5. 1,24-dihydroxycholecalciferol

6. 1,24-dihydroxyvitamin D3

7. Curatoderm

8. Pri-2191

2.3.2 Depositor-Supplied Synonyms

1. 57333-96-7

2. Bonalfa

3. Curatoderm

4. Tacalcitolum

5. Tv-02h

6. Tv-02

7. Unii-c2w72oj5zu

8. Pri 2191

9. 1-alpha,24(r)-dihydroxyvitamin D3

10. (1r,3s,5z)-5-[(2e)-2-[(1r,3as,7ar)-1-[(2r,5r)-5-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1h-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol

11. Tv 02

12. Pri-2191

13. C2w72oj5zu

14. 1.alpha.,24-dihydroxyvitamin D3

15. 1alpha,24(r)-dihydroxyvitamin D3

16. Tacalcitol (inn)

17. Tacalcitol [inn]

18. 1,24-dihydroxyvitamin D3

19. (24r)-1alpha,24-dihydroxyvitamin D3 / (24r)-1alpha,24-dihydroxycholecalciferol

20. (5z,7e)-(1s,3r,24r)-9,10-seco-5,7,10(19)-cholestatriene-1,3,24-triol

21. (1r,3s,z)-5-((e)-2-((1r,3as,7ar)-1-((2r,5r)-5-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1h-inden-4(2h)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol

22. Bonalfa (tn)

23. Tacalcitolum [inn-latin]

24. 1,24(r)-dihydroxyvitamin D3

25. Chebi:32176

26. Tacalcitol [inn:ban:jan]

27. Vellutan

28. Apsor

29. Ccris 4211

30. Tv02

31. Tacalcitol [mi]

32. 1alpha,24(oh)2d3

33. Schembl3945

34. Tacalcitol [mart.]

35. Tacalcitol [who-dd]

36. Tv-02hs

37. 1a,24-dihydroxycholecalciferol

38. Gtpl2780

39. Chembl2105611

40. Tacalcitol, >=99% (hplc)

41. Dtxsid90905111

42. Ex-a4429

43. Zinc4474668

44. Bdbm50441892

45. Lmst03020256

46. Akos024458008

47. Cs-0391

48. Db13689

49. (1-alpha,3-beta,5z,7e,24r)-9,10-secocholesta-5,7,10(19)-triene-1,3,24-triol

50. As-77643

51. Hy-32337

52. (1alpha,24r)-1,24-dihydroxyvitamin D3

53. 1.alpha.,24-dihydroxycholecalciferol

54. D08554

55. 333t967

56. Q155682

57. 1,24(r)-dihydroxyvitamin D3;1.alpha.,24r-dihydroxyvitamin D3

58. (1s,3r,5z,7e,24r)-9,10-secocholesta-5,7,10-triene-1,3,24-triol

59. (+)-(5z,7e,24r)-9,10-secocholesta-5,7,10(19)-triene-1alpha,3beta,24-triol

60. (1?,3?,5z,7e,24r)-9,10-secocholesta-5,7,10(19)-triene-1,3,24-triol

61. 1s,3r,5z,7e,24r)-9,10-secocholesta-5,7,10-triene-1,3,24-triol

62. 9,10-secocholesta-5,7,10(19)-triene-1,3,24-triol, (1-alpha,3-beta,5z,7e,24r)-

63. (+)-(5z,7e,24r)-9,10-secocholesta-5,7,10(19)-triene-1.alpha.,3.beta.,24-triol

2.4 Create Date
2006-01-13
3 Chemical and Physical Properties
Molecular Weight 416.6 g/mol
Molecular Formula C27H44O3
XLogP35.3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count3
Rotatable Bond Count6
Exact Mass416.32904526 g/mol
Monoisotopic Mass416.32904526 g/mol
Topological Polar Surface Area60.7 Ų
Heavy Atom Count30
Formal Charge0
Complexity676
Isotope Atom Count0
Defined Atom Stereocenter Count7
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count2
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Inflammatory Agents

Substances that reduce or suppress INFLAMMATION. (See all compounds classified as Anti-Inflammatory Agents.)


Dermatologic Agents

Drugs used to treat or prevent skin disorders or for the routine care of skin. (See all compounds classified as Dermatologic Agents.)


4.2 ATC Code

D - Dermatologicals

D05 - Antipsoriatics

D05A - Antipsoriatics for topical use

D05AX - Other antipsoriatics for topical use

D05AX04 - Tacalcitol


Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty
Post Enquiry
POST ENQUIRY