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1. D-tagatose
2. Tagatose
3. Tagatose, (alpha-d)-isomer
4. Tagatose, (beta-d)-isomer
5. Tagatose, (d)-isomer
6. Tagatose, (dl)-isomer
1. 87-81-0
2. D-lyxo-hexulose
3. Lyxo-2-hexulose
4. 17598-81-1
5. Tagatose, D-
6. Naturlose
7. Keto-d-tagatose
8. Tagatose [nf]
9. Chebi:47693
10. T7a20y888y
11. Tagatose (nf)
12. Rel-(3s,4s,5r)-1,3,4,5,6-pentahydroxyhexan-2-one
13. Dl-tagatose
14. Einecs 201-772-3
15. Unii-t7a20y888y
16. Mfcd00134449
17. D-tagatose [mi]
18. D-tagatose [fcc]
19. Tagatose [mart.]
20. Tagatose [usp-rs]
21. Schembl4035
22. Tagatose, D- [ii]
23. Chembl1236183
24. Zinc2516866
25. D-(-)-tagatose, >=98.5%
26. S5387
27. D-(-)-tagatose, Analytical Standard
28. Akos015856492
29. Akos015902493
30. Ccg-266424
31. Db04936
32. Ncgc00248704-01
33. As-44378
34. Hy-42680
35. Cs-0028435
36. T1501
37. D09007
38. Wurcs=2.0/1,1,0/[ho112h]/1/
39. 134t449
40. Q414089
41. W-200517
42. Tagatose, United States Pharmacopeia (usp) Reference Standard
| Molecular Weight | 180.16 g/mol |
|---|---|
| Molecular Formula | C6H12O6 |
| XLogP3 | -3.2 |
| Hydrogen Bond Donor Count | 5 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 5 |
| Exact Mass | 180.06338810 g/mol |
| Monoisotopic Mass | 180.06338810 g/mol |
| Topological Polar Surface Area | 118 Ų |
| Heavy Atom Count | 12 |
| Formal Charge | 0 |
| Complexity | 147 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 3 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Intended for use as a therapeutic adjunct in the treatment of type II diabetes.
Oral tagatose significantly blunts the rise in plasma glucose seen after oral glucose in patients with diabetes mellitus in a dose-dependent manner without significantly affecting insulin levels. The minimal elevation of plasma tagatose levels in normal patients and the adverse gastrointestinal effects seen following larger doses of tagatose support poor absorption of this hexose and suggest that tagatose may act by attenuating glucose absorption in the intestine.
Iron Chelating Agents
Organic chemicals that form two or more coordination links with an iron ion. Once coordination has occurred, the complex formed is called a chelate. The iron-binding porphyrin group of hemoglobin is an example of a metal chelate found in biological systems. (See all compounds classified as Iron Chelating Agents.)
Absorption
Only 15-20 percent of tagatose is absorbed in the small intestine.
Tagatose does not influence the level of blood glucose nor insulin levels.
he steps in the metabolism of tagatose are identical to those for fructose or fruit sugar but tagatose is incompletely absorbed. Only 15-20 percent of tagatose is absorbed in the small intestine. The major part of ingested tagatose is fermented in the colon by indigenous microflora, resulting in the production of short-chain fatty acids. The short chain fatty acids are absorbed almost completely and metabolized.
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REF. STANDARDS & IMPURITIES
ABOUT THIS PAGE
A Tagatose manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Tagatose, including repackagers and relabelers. The FDA regulates Tagatose manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Tagatose API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Tagatose supplier is an individual or a company that provides Tagatose active pharmaceutical ingredient (API) or Tagatose finished formulations upon request. The Tagatose suppliers may include Tagatose API manufacturers, exporters, distributors and traders.
click here to find a list of Tagatose suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
A Tagatose DMF (Drug Master File) is a document detailing the whole manufacturing process of Tagatose active pharmaceutical ingredient (API) in detail. Different forms of Tagatose DMFs exist exist since differing nations have different regulations, such as Tagatose USDMF, ASMF (EDMF), JDMF, CDMF, etc.
A Tagatose DMF submitted to regulatory agencies in the US is known as a USDMF. Tagatose USDMF includes data on Tagatose's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Tagatose USDMF is kept confidential to protect the manufacturer’s intellectual property.
click here to find a list of Tagatose suppliers with USDMF on PharmaCompass.
Tagatose Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Tagatose GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Tagatose GMP manufacturer or Tagatose GMP API supplier for your needs.
A Tagatose CoA (Certificate of Analysis) is a formal document that attests to Tagatose's compliance with Tagatose specifications and serves as a tool for batch-level quality control.
Tagatose CoA mostly includes findings from lab analyses of a specific batch. For each Tagatose CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Tagatose may be tested according to a variety of international standards, such as European Pharmacopoeia (Tagatose EP), Tagatose JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Tagatose USP).
