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    Chemistry

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    Also known as:
    Molecular Formula
    C19H14F2N6O
    Molecular Weight
    380.4  g/mol
    InChI Key
    IUEWAGVJRJORLA-HZPDHXFCSA-N
    Talazoparib
    1 2D Structure

    Talazoparib

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (11S,12R)-7-fluoro-11-(4-fluorophenyl)-12-(2-methyl-1,2,4-triazol-3-yl)-2,3,10-triazatricyclo[7.3.1.05,13]trideca-1(13),5,7,9-tetraen-4-one
    2.1.2 InChI
    InChI=1S/C19H14F2N6O/c1-27-18(22-8-23-27)15-16(9-2-4-10(20)5-3-9)24-13-7-11(21)6-12-14(13)17(15)25-26-19(12)28/h2-8,15-16,25H,1H3,(H,26,28)/t15-,16-/m1/s1
    2.1.3 InChI Key
    IUEWAGVJRJORLA-HZPDHXFCSA-N
    2.1.4 Canonical SMILES
    CN1C(=NC=N1)C2C(N=C3C=C(C=C4C3=C2NNC4=O)F)C5=CC=C(C=C5)F
    2.1.5 Isomeric SMILES
    CN1C(=NC=N1)[C@@H]2[C@H](N=C3C=C(C=C4C3=C2NNC4=O)F)C5=CC=C(C=C5)F
    2.2 Create Date
    2010-03-15
    3 Chemical and Physical Properties
    Molecular Weight 380.4 g/mol
    Molecular Formula C19H14F2N6O
    XLogP31.4
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count7
    Rotatable Bond Count2
    Exact Mass380.11971542 g/mol
    Monoisotopic Mass380.11971542 g/mol
    Topological Polar Surface Area84.2 A^2
    Heavy Atom Count28
    Formal Charge0
    Complexity826
    Isotope Atom Count0
    Defined Atom Stereocenter Count2
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1

    API Reference Price

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    [{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q3","strtotime":1625509800,"product":"TALAZOPARIB TOSYLATE STANDARD","address":"HOTEL DREAMZ PARK OFFICE COMPLEX\\r\\nUNIT G, 571\/2, ANNA SALAI,\\r\\nTEYNAMPET, CHENNAI, TAMIL NADU.","city":"CHENNAI,","supplier":"FAREVA","supplierCountry":"GERMANY","foreign_port":"MUNICH","customer":"PFIZER INC","customerCountry":"INDIA","quantity":"0.10","actualQuantity":"100","unit":"GMS","unitRateFc":"0.1","totalValueFC":"12","currency":"EUR","unitRateINR":"9","date":"06-Jul-2021","totalValueINR":"898","totalValueInUsd":"12","indian_port":"MADRAS AIR","hs_no":"29339990","bill_no":"4582293","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"MUNICH","supplierAddress":"","customerAddress":"HOTEL DREAMZ PARK OFFICE COMPLEX\\r\\nUNIT G, 571\/2, ANNA SALAI,\\r\\nTEYNAMPET, CHENNAI, TAMIL NADU."}]
    06-Jul-2021
    06-Jul-2021
    KGS
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    Average Price (USD/KGS)

    Number of Transactions

    Total Quantity (KGS)

    Total Value (USD)

    Quantity (KGS) & Unit rate (USD/KGS) over time

    API Imports and Exports

    Importing Country Total Quantity
    (KGS)    		 Average Price
    (USD/KGS)    		 Number of Transactions

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    Finished Drug Prices

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    01

    Brand Name : Talzenna

    U.S.A
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    Pfizer AG

    Talazoparib

    Dosage Form : Caps

    Dosage Strength : 0.25mg

    Price Per Pack (Euro) : 1557.04

    Published in :

    Country : Switzerland

    RX/OTC/DISCN : Class A

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    Brand Name : Talzenna

    U.S.A
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    Antibody Engineering
    Not Confirmed

    Brand Name : Talzenna

    U.S.A
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    Antibody Engineering
    Not Confirmed

    Pfizer AG

    Talazoparib

    Dosage Form : Caps

    Dosage Strength : 1mg

    Price Per Pack (Euro) : 4674.98

    Published in :

    Country : Switzerland

    RX/OTC/DISCN : Class A

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    03

    Brand Name : Talzenna

    U.S.A
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    Antibody Engineering
    Not Confirmed

    Brand Name : Talzenna

    U.S.A
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    Antibody Engineering
    Not Confirmed

    Pfizer Europe MA EEIG

    Talazoparib

    Dosage Form : Kapsel, hard

    Dosage Strength : 0.1 mg

    Price Per Pack (Euro) : 1,492.55

    Published in :

    Country : Norway

    RX/OTC/DISCN :

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