Synopsis
Synopsis
0
CEP/COS
0
JDMF
0
EU WC
0
KDMF
0
NDC API
0
VMF
0
EDQM
0
USP
0
JP
0
Others
0
FDA Orange Book
0
Europe
0
Australia
0
South Africa
DRUG PRODUCT COMPOSITIONS
0
US Patents
0
US Exclusivities
0
Health Canada Patents
US Medicaid
NA
Annual Reports
NA
Regulatory FDF Prices
NA
0
FDF
0
Stock Recap #PipelineProspector
0
Weekly News Recap #Phispers
1. Talc
2. Talcum Powder
1. 14807-96-6
2. Pulvistalci
3. Magnesium Silicate, Hydrous
4. 13376-74-4
5. Magnesium Silicate Monohydrate (talc)
6. Mfcd00792903
7. 78229-94-4
8. Purified Talc
9. Talc Nanoparticles
10. Talc, Cp
11. Talc, -350 Mesh
12. Talc, Powder, 10 Mum
13. Magnesiumsilicatemonohydrate325m
14. Talc, Vetec(tm) Reagent Grade
15. Chembl3989756
16. Magnesium Silicate Xhydrate 800m
17. Talc, Tested According To Ph.eur.
18. Magnesium Silicate Monohydrate 325m
19. Ft-0645101
20. Ab01568263_01
21. Talc, Meets Analytical Specification Of Ph.??eur., Bp, Powder
22. 149925-00-8
Molecular Weight | 379.27 g/mol |
---|---|
Molecular Formula | H2Mg3O12Si4 |
Hydrogen Bond Donor Count | 1 |
Hydrogen Bond Acceptor Count | 12 |
Rotatable Bond Count | 0 |
Exact Mass | 377.8174567 g/mol |
Monoisotopic Mass | 377.8174567 g/mol |
Topological Polar Surface Area | 189 Ų |
Heavy Atom Count | 19 |
Formal Charge | 0 |
Complexity | 20.3 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 8 |
Talc intrapleural aerosol is indicated to prevent recurrence of malignant pleural effusions in symptomatic patients. It is administered during thoracoscopy or open thoracotomy.
Thomson.Micromedex. Drug Information for the Health Care Professional. 24th ed. Volume 1. Plus Updates. Content Reviewed by the United States Pharmacopeial Convention, Inc. Greenwood Village, CO. 2004.
...Talc insufflation, either as a poudrage or by using slurry, is recognized as an effective treatment /for spontaneous pneumothorax/.
PMID:14602332 Milton R, Cale AR; Ann Thorac Surg 76 (5): 1740-1 (2003)
...The case of a 78 yr-old man /is presented,/ who was treated with talc pleurodesis for recurrent pleural effusion and subsequently developed a massive hemothorax, a rare complication.
PMID:15384468 Hirota B et al; Hawaii Med J 63 (7): 208-10 (2004)
/The case of/ ...a young woman with a large, calcified anterior mediastinal mass discovered 18 months following a left talc pleurodesis /is reported/.
PMID:12607675 Ahmed Z, Shrager JB; Ann Thorac Surg 75 (2): 568-9 (2003)
Antiperspirants
Agents that are put on the SKIN to reduce SWEATING or prevent excess sweating (HYPERHIDROSIS). (See all compounds classified as Antiperspirants.)
Foreign body granulomas containing talc fibers are to be found in lung, pleura, diaphragm, pericardium, and gastric wall ... .
Hamilton, A., and H. L. Hardy. Industrial Toxicology. 3rd ed. Acton, Mass.: Publishing Sciences Group, Inc., 1974., p. 441
...Transmission electron microscopy and energy dispersive X-ray spectroscopy /was used to analyze/ the total fibrous and nonfibrous mineral content of the lungs of a series of 14 male smokers with lung cancer but with no history of occupational dust exposure, and of a series of 14 control men matched by age, smoking history and general occupational class. The average concentration of mineral fibers and nonfiberous particles were 3.8 and 2.0 times higher in the group with cancer. Kaolinite, talc, mica, feldspars and crystalline silica comprised the majority of fibrous and nonfibrous particles in both groups.
IARC. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Geneva: World Health Organization, International Agency for Research on Cancer, 1972-PRESENT. (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V42 208 (1987)
Mice that received a sterile sc injection of talc were studied by measuring the incorporation of radioactive leucine and glucosamine into liver and plasma protein and the talc gramuloma at various intervals between 2 and 528 hours after injection. Incorporation into plasma proteins indicated a biphasic response with a marked increased incorporation into the perchloric acid insoluble fraction at 21 hours, a return to normal values at 45 hours, and a similar marked increase into the perchloric acid soluble fraction at 45 hours with a gradual return toward normal values. The response was dependent upon the amount of talc injected.
Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V1 526
Using radioactive tracer techniques in rats, mice, guinea pigs, and hamsters, no intestinal absorption or translocation of ingested talc to the liver and kidneys was detected.
Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V1 527
For more Absorption, Distribution and Excretion (Complete) data for TALC (7 total), please visit the HSDB record page.
In hamsters, ...the biological half-life of talc deposited in the alveoli was 7-10 days, and the alveolar clearance was basically complete 4 months after exposure.
Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V1 526
API/FDF Prices: Book a Demo to explore the features and consider upgrading later
API Imports and Exports
Importing Country | Total Quantity (KGS) |
Average Price (USD/KGS) |
Number of Transactions |
---|
Upgrade, download data, analyse, strategize, subscribe with us
Related Excipient Companies
Excipients by Applications
Market Place
ABOUT THIS PAGE
31
PharmaCompass offers a list of Talc API API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Talc API manufacturer or Talc API supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Talc API manufacturer or Talc API supplier.
PharmaCompass also assists you with knowing the Talc API API Price utilized in the formulation of products. Talc API API Price is not always fixed or binding as the Talc API Price is obtained through a variety of data sources. The Talc API Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.
A Talc-Supplied by Selleck Chemicals manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Talc-Supplied by Selleck Chemicals, including repackagers and relabelers. The FDA regulates Talc-Supplied by Selleck Chemicals manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Talc-Supplied by Selleck Chemicals API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
click here to find a list of Talc-Supplied by Selleck Chemicals manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.
A Talc-Supplied by Selleck Chemicals supplier is an individual or a company that provides Talc-Supplied by Selleck Chemicals active pharmaceutical ingredient (API) or Talc-Supplied by Selleck Chemicals finished formulations upon request. The Talc-Supplied by Selleck Chemicals suppliers may include Talc-Supplied by Selleck Chemicals API manufacturers, exporters, distributors and traders.
click here to find a list of Talc-Supplied by Selleck Chemicals suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
A Talc-Supplied by Selleck Chemicals DMF (Drug Master File) is a document detailing the whole manufacturing process of Talc-Supplied by Selleck Chemicals active pharmaceutical ingredient (API) in detail. Different forms of Talc-Supplied by Selleck Chemicals DMFs exist exist since differing nations have different regulations, such as Talc-Supplied by Selleck Chemicals USDMF, ASMF (EDMF), JDMF, CDMF, etc.
A Talc-Supplied by Selleck Chemicals DMF submitted to regulatory agencies in the US is known as a USDMF. Talc-Supplied by Selleck Chemicals USDMF includes data on Talc-Supplied by Selleck Chemicals's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Talc-Supplied by Selleck Chemicals USDMF is kept confidential to protect the manufacturer’s intellectual property.
click here to find a list of Talc-Supplied by Selleck Chemicals suppliers with USDMF on PharmaCompass.
Talc-Supplied by Selleck Chemicals Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Talc-Supplied by Selleck Chemicals GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Talc-Supplied by Selleck Chemicals GMP manufacturer or Talc-Supplied by Selleck Chemicals GMP API supplier for your needs.
A Talc-Supplied by Selleck Chemicals CoA (Certificate of Analysis) is a formal document that attests to Talc-Supplied by Selleck Chemicals's compliance with Talc-Supplied by Selleck Chemicals specifications and serves as a tool for batch-level quality control.
Talc-Supplied by Selleck Chemicals CoA mostly includes findings from lab analyses of a specific batch. For each Talc-Supplied by Selleck Chemicals CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Talc-Supplied by Selleck Chemicals may be tested according to a variety of international standards, such as European Pharmacopoeia (Talc-Supplied by Selleck Chemicals EP), Talc-Supplied by Selleck Chemicals JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Talc-Supplied by Selleck Chemicals USP).