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Chemistry

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Also known as: 481-53-8, Tangeritin, Ponkanetin, Pentamethoxyflavone, 4',5,6,7,8-pentamethoxyflavone, 5,6,7,8,4'-pentamethoxyflavone
Molecular Formula
C20H20O7
Molecular Weight
372.4  g/mol
InChI Key
ULSUXBXHSYSGDT-UHFFFAOYSA-N
FDA UNII
I4TLA1DLX6

Tangeretin
tangeretin is a natural product found in Ficus erecta var. beecheyana, Citrus tankan, and other organisms with data available.
1 2D Structure

Tangeretin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
5,6,7,8-tetramethoxy-2-(4-methoxyphenyl)chromen-4-one
2.1.2 InChI
InChI=1S/C20H20O7/c1-22-12-8-6-11(7-9-12)14-10-13(21)15-16(23-2)18(24-3)20(26-5)19(25-4)17(15)27-14/h6-10H,1-5H3
2.1.3 InChI Key
ULSUXBXHSYSGDT-UHFFFAOYSA-N
2.1.4 Canonical SMILES
COC1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C(=C(C(=C3OC)OC)OC)OC
2.2 Other Identifiers
2.2.1 UNII
I4TLA1DLX6
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 4',5,6,7,8-pentamethoxy-flavone

2. 4',5,6,7,8-pentamethoxyflavone

3. Tangeritin

2.3.2 Depositor-Supplied Synonyms

1. 481-53-8

2. Tangeritin

3. Ponkanetin

4. Pentamethoxyflavone

5. 4',5,6,7,8-pentamethoxyflavone

6. 5,6,7,8,4'-pentamethoxyflavone

7. 5,6,7,8-tetramethoxy-2-(4-methoxyphenyl)chromen-4-one

8. 4h-1-benzopyran-4-one, 5,6,7,8-tetramethoxy-2-(4-methoxyphenyl)-

9. 5,6,7,8-tetramethoxy-2-(4-methoxyphenyl)-4h-chromen-4-one

10. Nsc 53909

11. 5,6,7,8-tetramethoxy-2-(4-methoxyphenyl)-4-benzopyrone

12. Nsc53909

13. Nsc-53909

14. I4tla1dlx6

15. Flavone, 4',5,6,7,8-pentamethoxy-

16. Chembl73930

17. Mls002667634

18. Chebi:9400

19. 4h-1-benzopyran-4-one, 5,6,7,8-tetramethoxy-2-(p-methoxyphenyl)-

20. 5,6,7,8-tetramethoxy-2-(4-methoxyphenyl)-4h-1-benzopyran-4-one

21. Nsc618905

22. Flavone, 5,6,7,8,4'-pentamethoxy

23. Nsc-618905

24. Tangeritin; Nsc53909; Nsc618905

25. Tangeretin (6ci)

26. Einecs 207-570-1

27. Unii-i4tla1dlx6

28. Brn 0351695

29. Ai3-23869

30. 4',5,6,7,8-pentamethoxy-flavone

31. Mfcd00017438

32. Tangeretin;tangeratin

33. Tangeretin (tangeritin)

34. 2-(4-methoxyphenyl)-5,6,7,8-tetramethoxy-4h-1-benzopyran-4-one

35. Spectrum2_001698

36. Spectrum3_000920

37. Spectrum4_001019

38. Tangeritin [inci]

39. Tangeretin [who-dd]

40. Schembl19740

41. Kbiogr_001517

42. 5-18-05-00491 (beilstein Handbook Reference)

43. Flavone, 4',5,6,7,8-pentamethoxy- (7ci,8ci)

44. Spectrum1505269

45. Spbio_001656

46. Tangeretin, Analytical Standard

47. Megxp0_001011

48. Tangeretin, >=95% (hplc)

49. Acon1_001263

50. Kbio3_001900

51. Dtxsid30197417

52. Flavone,5,6,7,8-pentamethoxy-

53. Hms3651a22

54. Hy-n0133

55. Zinc1531699

56. 4'',5,6,7,8-pentamethoxyflavone

57. 4h-1-benzopyran-4-one, 2-(4-methoxyphenyl)-5,6,7,8-tetramethoxy-

58. 5,6,7,8,4''-pentamethoxyflavone

59. Bdbm50209218

60. Ccg-38782

61. Lmpk12111443

62. S2363

63. Akos015895209

64. Ac-1699

65. Cs-5484

66. Nsc 618905

67. Sdccgmls-0066766.p001

68. Ncgc00095850-01

69. Ncgc00095850-02

70. Ncgc00169520-01

71. As-11637

72. Nci60_004330

73. Smr001557394

74. Ft-0632194

75. N2077

76. Sw219232-1

77. T2708

78. 481t538

79. A827490

80. Sr-05000002625

81. Cu-01000013437-2

82. Q-100525

83. Q1748737

84. Sr-05000002625-1

85. Brd-k25186396-001-02-1

86. Brd-k25186396-001-04-7

87. 4h-1-benzopyran-4-one,6,7,8-tetramethoxy-2-(4-methoxyphenyl)-

88. 4h-1-benzopyran-4-one,6,7,8-tetramethoxy-2-(p-methoxyphenyl)-

89. 4h-1-benzopyran-4-one, 5,6,7,8-tetra-methoxy-2-(4-methoxyphenyl)-

90. 5,6,7,8-tetramethoxy-2-(4-methoxyphenyl)-4h-1-benzopyran-4-one, 9ci

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 372.4 g/mol
Molecular Formula C20H20O7
XLogP33
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count7
Rotatable Bond Count6
Exact Mass372.12090297 g/mol
Monoisotopic Mass372.12090297 g/mol
Topological Polar Surface Area72.4 Ų
Heavy Atom Count27
Formal Charge0
Complexity540
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 Metabolism/Metabolites

Tangeretin has known human metabolites that include 4'-Hydroxy-5,6,7,8-tetramethoxyflavone and 5,6-Dihydroxy-7,8,4'-trimethoxyflavone.

S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560


ABOUT THIS PAGE

Tangeretin Manufacturers

A Tangeretin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Tangeretin, including repackagers and relabelers. The FDA regulates Tangeretin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Tangeretin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Tangeretin manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Tangeretin Suppliers

A Tangeretin supplier is an individual or a company that provides Tangeretin active pharmaceutical ingredient (API) or Tangeretin finished formulations upon request. The Tangeretin suppliers may include Tangeretin API manufacturers, exporters, distributors and traders.

click here to find a list of Tangeretin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Tangeretin GMP

Tangeretin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Tangeretin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Tangeretin GMP manufacturer or Tangeretin GMP API supplier for your needs.

Tangeretin CoA

A Tangeretin CoA (Certificate of Analysis) is a formal document that attests to Tangeretin's compliance with Tangeretin specifications and serves as a tool for batch-level quality control.

Tangeretin CoA mostly includes findings from lab analyses of a specific batch. For each Tangeretin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Tangeretin may be tested according to a variety of international standards, such as European Pharmacopoeia (Tangeretin EP), Tangeretin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Tangeretin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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