Find Tc-99M Tetrofosmin manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: Technetium tc-99m tetrofosmin, Q7692231
Molecular Formula
C18H40O4P2Tc
Molecular Weight
479.4  g/mol
InChI Key
BDMZPZIFZPWFFW-UHFFFAOYSA-N

Tc-99M Tetrofosmin
Technetium Tc-99m Tetrofosmin is a radiopharmaceutical consisting of tetrofosmin, composed of two bidentate diphosphine ligands chelating the metastable radioisotope technetium Tc-99 (99mTc), with potential imaging activity upon SPECT (single photon emission computed tomography). Upon administration, technetium Tc 99m tetrofosmin is preferentially taken up by, and accumulates in, myocardial cells. Upon imaging, myocardial cells can be visualized and changes in ischemia and/or perfusion can be detected.
1 2D Structure

Tc-99M Tetrofosmin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-[bis(2-ethoxyethyl)phosphanyl]ethyl-bis(2-ethoxyethyl)phosphane;technetium
2.1.2 InChI
InChI=1S/C18H40O4P2.Tc/c1-5-19-9-13-23(14-10-20-6-2)17-18-24(15-11-21-7-3)16-12-22-8-4;/h5-18H2,1-4H3;
2.1.3 InChI Key
BDMZPZIFZPWFFW-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCOCCP(CCOCC)CCP(CCOCC)CCOCC.[Tc]
2.2 Synonyms
2.2.1 MeSH Synonyms

1. 99mtc-tetrafosmin

2. 99mtc-tetrofosmin

3. Myoview

4. Ppn-1011

5. Ppn1011

6. Tc-99m-ppn1011

7. Tc-99m-tetrofosmin

8. Technetium Tc 99m 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane

9. Technetium Tc-99m Tetrofosmin

10. Technetium(1+)-99tc, Bis(6,9-bis(2-ethoxyethyl)-3,12-dioxa-6,9-diphosphatetradecane-.kappa.p,.kappa.p')dioxo-, (oc-6-11)-

11. Technetium-99m-tetrofosmin

2.2.2 Depositor-Supplied Synonyms

1. Technetium Tc-99m Tetrofosmin

2. Q7692231

2.3 Create Date
2014-03-06
3 Chemical and Physical Properties
Molecular Weight 479.4 g/mol
Molecular Formula C18H40O4P2Tc
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count19
Exact Mass479.14654 g/mol
Monoisotopic Mass479.14654 g/mol
Topological Polar Surface Area36.9 Ų
Heavy Atom Count25
Formal Charge0
Complexity201
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Radiopharmaceuticals

Compounds that are used in medicine as sources of radiation for radiotherapy and for diagnostic purposes. They have numerous uses in research and industry. (Martindale, The Extra Pharmacopoeia, 30th ed, p1161) (See all compounds classified as Radiopharmaceuticals.)


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ABOUT THIS PAGE

Tc-99M Tetrofosmin Manufacturers

A Tc-99M Tetrofosmin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Tc-99M Tetrofosmin, including repackagers and relabelers. The FDA regulates Tc-99M Tetrofosmin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Tc-99M Tetrofosmin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Tc-99M Tetrofosmin Suppliers

A Tc-99M Tetrofosmin supplier is an individual or a company that provides Tc-99M Tetrofosmin active pharmaceutical ingredient (API) or Tc-99M Tetrofosmin finished formulations upon request. The Tc-99M Tetrofosmin suppliers may include Tc-99M Tetrofosmin API manufacturers, exporters, distributors and traders.

Tc-99M Tetrofosmin GMP

Tc-99M Tetrofosmin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Tc-99M Tetrofosmin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Tc-99M Tetrofosmin GMP manufacturer or Tc-99M Tetrofosmin GMP API supplier for your needs.

Tc-99M Tetrofosmin CoA

A Tc-99M Tetrofosmin CoA (Certificate of Analysis) is a formal document that attests to Tc-99M Tetrofosmin's compliance with Tc-99M Tetrofosmin specifications and serves as a tool for batch-level quality control.

Tc-99M Tetrofosmin CoA mostly includes findings from lab analyses of a specific batch. For each Tc-99M Tetrofosmin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Tc-99M Tetrofosmin may be tested according to a variety of international standards, such as European Pharmacopoeia (Tc-99M Tetrofosmin EP), Tc-99M Tetrofosmin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Tc-99M Tetrofosmin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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