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1. 99mtc Mebrofenin
2. Bridatec
3. Tc-99m-3-bromo-2,4,6-trimethyl-ida
4. Tc-99m-3-bromo-2,4,6-trimethyliminodiacetic Acid
5. Tc-99m-br-ida
6. Tc-99m-brida
7. Tc-99m-btm-ida
8. Tc-99m-n-(2,4,6-trimethylbromoacetanilide)iminodiacetate
9. Tc-99m-sq 26,962
10. Tc-99m-tbida
11. Tc-99m-trimethyl-brida
12. Tc-99m-trimethylbromo-ida
13. Tc-99m-trimethylbromoimino-diacetic Acid
14. Tc-99m-trimethylbromoiminodiacetate
15. Tc-choletec
16. Tc-tmb-ida
17. Technetium Tc 99m 3-bromo-2,4,6-trimethyliminodiacetic Acid
18. Technetium Tc 99m Mebrofenin
19. Technetium Tc 99m-trimethylbromo-ida
1. Technetium Tc 99m Mebrofenin
2. Technetium Tc-99m Mebrofenin
3. Technetium (99mtc) Mebrofenin
4. 1415247-71-0
5. 2-[[2-(3-bromo-2,4,6-trimethylanilino)-2-oxoethyl]-(carboxymethyl)amino]acetic Acid;technetium-99
6. Mebrofenin / 99tc
7. Mebrofenin / Technetium-99tc
8. 99mtc-mebrofenin
9. Mebrofenin Mixture With Technetium-99tc
10. Technetium Tc-99m Mebrofenin Kit
11. Technetium Tc 99m Disida
12. F2nq468l52
13. Db09137
14. Glycine, N-(2-((3-bromo-2,4,6-trimethylphenyl)amino)-2-oxoethyl)-n-(carboxymethyl)-, Technetium-99tc Salt
15. Technetium Tc 99m Mebrofenin [usan]
16. Technetium Tc 99m Mebrofenin [who-dd]
17. Technetium Tc 99m Diisopropyl-iminodiacetic Acid
18. Q7692227
19. Technetium Tc 99m Mebrofenin [usp Impurity]
20. Q22075852
21. Bis(2-[[2-(3-bromo-2,4,6-trimethylanilino)-2-oxoethyl]-(carboxymethyl)amino]acetate) Technetium
| Molecular Weight | 486.13 g/mol |
|---|---|
| Molecular Formula | C15H19BrN2O5Tc |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 7 |
| Exact Mass | 484.95398 g/mol |
| Monoisotopic Mass | 484.95398 g/mol |
| Topological Polar Surface Area | 107 Ų |
| Heavy Atom Count | 24 |
| Formal Charge | 0 |
| Complexity | 443 |
| Isotope Atom Count | 1 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 2 |
Technetium Tc 99m Mebrofenin is indicated as a hepatobiliary imaging agent.
FDA Label
Radiopharmaceuticals
Compounds that are used in medicine as sources of radiation for radiotherapy and for diagnostic purposes. They have numerous uses in research and industry. (Martindale, The Extra Pharmacopoeia, 30th ed, p1161) (See all compounds classified as Radiopharmaceuticals.)
V - Various
V09 - Diagnostic radiopharmaceuticals
V09D - Hepatic and reticulo endothelial system
V09DA - Technetium (99mtc) compounds
V09DA04 - Technetium (99mTc) mebrofenin
Absorption
Visualisation in the liver could be detected by 5 minutes and maximum liver uptake occurred at 11 minutes post-injection. Hepatic duct and gallbladder visualization occurred by 10 to 15 minutes and intestinal activity was visualized by 30 to 60 minutes in subjects with normal hepatobiliary function The mean percent injected dose remaining in the blood at 10 minutes was 17%.
Route of Elimination
The mean percent injected dose excreted in the urine during the first 3 hours was 1%.
Clearance
Following intravenous administration in normal subjects, Technetium Tc 99m Mebrofenin was rapidly cleared from the circulation.
Technetium Tc 99m decays by isomeric transition with a physical half-life of 6.02 hours.
Technetium Tc 99m Mebrofenin has no known pharmacologic activity at the recommended doses. It is used as a diagnostic agent as Technetium-99m decays by isomeric transition to technetium-99 through the release of a detectable gamma ray.
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