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Chemistry

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Also known as: Technetium tc 99m pentetate, Technetium tc 99m pentetate [usp], Techneplex, Vw78417pu1, 65454-61-7, Unii-vw78417pu1
Molecular Formula
C14H18N3NaO10Tc-4
Molecular Weight
510.20  g/mol
InChI Key
UBRBVRZQCLXKSZ-FCHARDOESA-I

Techneplex
A technetium imaging agent used in renal scintigraphy, computed tomography, lung ventilation imaging, gastrointestinal scintigraphy, and many other procedures which employ radionuclide imaging agents.
1 2D Structure

Techneplex

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
sodium;2-[bis[2-[bis(carboxylatomethyl)amino]ethyl]amino]acetate;technetium-99
2.1.2 InChI
InChI=1S/C14H23N3O10.Na.Tc/c18-10(19)5-15(1-3-16(6-11(20)21)7-12(22)23)2-4-17(8-13(24)25)9-14(26)27;;/h1-9H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25)(H,26,27);;/q;+1;/p-5/i;;1+1
2.1.3 InChI Key
UBRBVRZQCLXKSZ-FCHARDOESA-I
2.1.4 Canonical SMILES
C(CN(CC(=O)[O-])CC(=O)[O-])N(CCN(CC(=O)[O-])CC(=O)[O-])CC(=O)[O-].[Na+].[Tc]
2.1.5 Isomeric SMILES
C(CN(CC(=O)[O-])CC(=O)[O-])N(CCN(CC(=O)[O-])CC(=O)[O-])CC(=O)[O-].[Na+].[99Tc]
2.2 Synonyms
2.2.1 MeSH Synonyms

1. 99m-dtpa, Tc

2. Pentetic Acid, Technetium

3. Tc 99m Dtpa

4. Tc 99m-dtpa

5. Tc-dtpa

6. Technetium (99m) Pentetate

7. Technetium Diethylenetriamine Pentaacetic Acid

8. Technetium Dtpa

9. Technetium Pentetic Acid

10. Technetium Tc 99m Pentetate

11. Technetium-dtpa

2.2.2 Depositor-Supplied Synonyms

1. Technetium Tc 99m Pentetate

2. Technetium Tc 99m Pentetate [usp]

3. Techneplex

4. Vw78417pu1

5. 65454-61-7

6. Unii-vw78417pu1

7. Technetium Tc 99m Pentetate Kit

8. Mpi Tc 99m Dtpa Kit (chelate)

9. Tc 99m Dtpa Kit

10. Tc 99m Dtpa Kit (chelate)

11. Sodium (n,n-bis(2-bis(carboxymethyl)amino)ethyl)glycinato(5-))-technetate(1-)-(sup 99m)tc

12. Human Serum Albumin Diethylenetriaminepentaacetic Acid Technetium((sup 99m)tc) Injection

13. Technetate(1-)-99tc, (n,n-bis(2-(bis(carboxymethyl)amino)ethyl)glycinato(5-))-, Sodium

14. Technetate(1-)(sup 99 M)tc, (n,n-bis(2-bis(carboxymethyl)amino)ethyl)glycinato(5-))-, Sodium

15. Technetate(1-)(sup 99m)tc, (n,n-bis(2-bis(carboxymethyl)amino)ethyl)glycinato(5-))-, Sodium

2.3 Create Date
2012-03-21
3 Chemical and Physical Properties
Molecular Weight 510.20 g/mol
Molecular Formula C14H18N3NaO10Tc-4
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count13
Rotatable Bond Count0
Exact Mass509.995238 g/mol
Monoisotopic Mass509.995238 g/mol
Topological Polar Surface Area210 Ų
Heavy Atom Count29
Formal Charge-4
Complexity488
Isotope Atom Count1
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Drug and Medication Information
4.1 Drug Information
1 of 2  
Drug NameAn-dtpa
PubMed HealthTechnetium Tc 99m Pentetate (Injection)
Drug ClassesDiagnostic Agent, Radiopharmaceutical Imaging
Active IngredientTechnetium tc-99m pentetate kit
Dosage FormInjectable
RouteInjection
Strengthn/a
Market StatusPrescription
CompanyJubilant Draximage

2 of 2  
Drug NameAn-dtpa
PubMed HealthTechnetium Tc 99m Pentetate (Injection)
Drug ClassesDiagnostic Agent, Radiopharmaceutical Imaging
Active IngredientTechnetium tc-99m pentetate kit
Dosage FormInjectable
RouteInjection
Strengthn/a
Market StatusPrescription
CompanyJubilant Draximage

5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Chelating Agents

Chemicals that bind to and remove ions from solutions. Many chelating agents function through the formation of COORDINATION COMPLEXES with METALS. (See all compounds classified as Chelating Agents.)


Radiopharmaceuticals

Compounds that are used in medicine as sources of radiation for radiotherapy and for diagnostic purposes. They have numerous uses in research and industry. (Martindale, The Extra Pharmacopoeia, 30th ed, p1161) (See all compounds classified as Radiopharmaceuticals.)


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ABOUT THIS PAGE

Techneplex Manufacturers

A Techneplex manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Techneplex, including repackagers and relabelers. The FDA regulates Techneplex manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Techneplex API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Techneplex Suppliers

A Techneplex supplier is an individual or a company that provides Techneplex active pharmaceutical ingredient (API) or Techneplex finished formulations upon request. The Techneplex suppliers may include Techneplex API manufacturers, exporters, distributors and traders.

Techneplex GMP

Techneplex Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Techneplex GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Techneplex GMP manufacturer or Techneplex GMP API supplier for your needs.

Techneplex CoA

A Techneplex CoA (Certificate of Analysis) is a formal document that attests to Techneplex's compliance with Techneplex specifications and serves as a tool for batch-level quality control.

Techneplex CoA mostly includes findings from lab analyses of a specific batch. For each Techneplex CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Techneplex may be tested according to a variety of international standards, such as European Pharmacopoeia (Techneplex EP), Techneplex JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Techneplex USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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