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Chemistry

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Also known as: Technetium-99, Technetium-99m, Technetium-99mtc, Technetium, isotope of mass 99, 99tc, Technetium 99m
Molecular Formula
Tc
Molecular Weight
98.906250  g/mol
InChI Key
GKLVYJBZJHMRIY-OUBTZVSYSA-N
FDA UNII
6EW75241VU

Technetium-99
Technetium TC-99m is one of the radioactive isotopes of technetium, a gamma/beta-emitter with a half life of 6 hours.
1 2D Structure

Technetium-99

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
technetium-99
2.1.2 InChI
InChI=1S/Tc/i1+1
2.1.3 InChI Key
GKLVYJBZJHMRIY-OUBTZVSYSA-N
2.1.4 Canonical SMILES
[Tc]
2.1.5 Isomeric SMILES
[99Tc]
2.2 Other Identifiers
2.2.1 UNII
6EW75241VU
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 99tc Radioisotope

2. Tc-99 Radioisotope

3. Technetium-99

2.3.2 Depositor-Supplied Synonyms

1. Technetium-99

2. Technetium-99m

3. Technetium-99mtc

4. Technetium, Isotope Of Mass 99

5. 99tc

6. Technetium 99m

7. 14133-76-7

8. Tc 99

9. Technetium Tc 99m

10. Technetium (99mtc)

11. Technetium, Tc-99m

12. Technetium (tc 99m)

13. 6ew75241vu

14. Cea-scan

15. Arcitumomab Technetium-99m

16. Technetium-99m Arcitumomab

17. Unii-029jf1scu8

18. Technegas

19. Technetium Tc 99m Arcitumomab

20. Unii-6ew75241vu

21. Cea Scan

22. Technetium,tc-99m

23. Tc-99m Arcitumomab

24. Arcitumomab 99mtc-labeled Form [mi]

25. Technetium-99m Arcitumomab [who-dd]

26. Technetium 99m Metal

27. 029jf1scu8

28. Arcitumomab 99mtc-labeled Form

29. Technetium (99mtc) Arcitumomab

30. (99)tc

31. Chebi:33371

32. Dtxsid00874006

33. Technetium Tc 99m [vandf]

34. Technetium,tc-99m [vandf]

35. Arcitumomab, Technetium-99m Labeled

36. (99)43tc

37. Technetium Tc 99m [who-dd]

38. Technetium (99mtc) Technegas

39. Db14227

40. Technetium (tc 99m) [vandf]

41. 154361-49-6

2.4 Create Date
2004-09-16
3 Chemical and Physical Properties
Molecular Weight 98.906250 g/mol
Molecular Formula Tc
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count0
Rotatable Bond Count0
Exact Mass98.906250 g/mol
Monoisotopic Mass98.906250 g/mol
Topological Polar Surface Area0 Ų
Heavy Atom Count1
Formal Charge0
Complexity0
Isotope Atom Count1
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Indication

CEA-Scan is indicated only in patients with histologically-demonstrated carcinoma of the colon or rectum for imaging of recurrence and/or metastases. CEA-Scan is employed for diagnostic use only, in the above mentioned patients, as an adjunct to standard non-invasive imaging techniques, such as ultrasonography or CT scan, in the following situations:

- Patients with evidence of recurrence and/or metastatic carcinoma of the colon or rectum, who are undergoing an evaluation for extent of disease, such as prior to surgical resection and/or other therapy, or

- Patients with suspected recurrence and/or metastatic carcinoma of the colon or rectum in association with rising levels of carcinoembryonic antigen (CEA).


5 Pharmacology and Biochemistry
5.1 ATC Code

V09IA01


V - Various

V09 - Diagnostic radiopharmaceuticals

V09E - Respiratory system

V09EA - Technetium (99mtc), inhalants

V09EA02 - Technetium (99mTc) technegas


V - Various

V09 - Diagnostic radiopharmaceuticals

V09I - Tumour detection

V09IA - Technetium (99mtc) compounds

V09IA06 - Technetium (99mTc) arcitumomab


DRUG PRODUCT COMPOSITIONS

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DOSAGE - INJECTABLE;INJECTION - N/A

USFDA APPLICATION NUMBER - 19981

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DOSAGE - INJECTABLE;INJECTION - N/A

USFDA APPLICATION NUMBER - 202207

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