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1. 3-methoxy-n-(3-(1-methyl-1h-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamide
2. Apd 791
3. Apd791
1. 887936-68-7
2. Apd791
3. Apd-791
4. Benzamide, 3-methoxy-n-[3-(1-methyl-1h-pyrazol-5-yl)-4-[2-(4-morpholinyl)ethoxy]phenyl]-
5. Chembl1084617
6. F42z27575a
7. 3-methoxy-n-[3-(2-methylpyrazol-3-yl)-4-(2-morpholin-4-ylethoxy)phenyl]benzamide
8. Benzamide,3-methoxy-n-[3-(1-methyl-1h-pyrazol-5-yl)-4-[2-(4-morpholinyl)ethoxy]phenyl]-
9. 3-methoxy-n-(3-(1-methyl-1h-pyrazol-5-yl)-4-(2-(morpholin-4- Yl)ethoxy)phenyl)benzamide
10. 3-methoxy-n-(3-(1-methyl-1h-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamide
11. 3-methoxy-n-(3-(2-methyl-2h-pyrazol-3-yl)-4-(2-morpholin-4-yl-ethoxy)-phenyl)- Benzamide
12. 3-methoxy-n-[3-(2-methyl-2h-pyrazol-3-yl)-4-(2-morpholin-4-yl-ethoxy)-phenyl]-benzamide
13. Benzamide, 3-methoxy-n-(3-(1-methyl-1h-pyrazol-5-yl)-4-(2-(4- Morpholinyl)ethoxy)phenyl)-
14. Temanogrel [usan]
15. Temanogrel [usan:inn]
16. Unii-f42z27575a
17. Apd 791
18. Benzamide,3-methoxy-n-(3-(1-methyl-1h-pyrazol-5-yl)-4-(2-(4-morpholinyl)ethoxy)phenyl)-
19. Temanogrel [inn]
20. Temanogrel (usan/inn)
21. Temanogrel [who-dd]
22. Apd791apd791
23. Schembl1166554
24. Dtxsid70237321
25. Chebi:177604
26. Bcp24269
27. Bdbm50319423
28. Zinc35920376
29. As-74248
30. Hy-10560
31. Cs-0002653
32. A17094
33. D09976
34. D84074
35. Q27277611
36. 3-methoxy-n-[3-(1-methyl-1h-pyrazol-5-yl)-4-[2-(morpholin-4-yl)ethoxy]phenyl]benzamide
37. 3-methoxy-n-[3-(2-methyl-2h-pyrazol-3-yl)-4-(2-morpholin-4-yl-ethoxy)phenyl]-benzamide
| Molecular Weight | 436.5 g/mol |
|---|---|
| Molecular Formula | C24H28N4O4 |
| XLogP3 | 2.3 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 8 |
| Exact Mass | 436.21105539 g/mol |
| Monoisotopic Mass | 436.21105539 g/mol |
| Topological Polar Surface Area | 77.8 Ų |
| Heavy Atom Count | 32 |
| Formal Charge | 0 |
| Complexity | 588 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
For the treatment and prophylaxis of arterial thrombosis.
APD791 is intended to lower the risk of arterial thrombosis by reducing the amplification of platelet aggregation, arterial constriction and intimal hyperplasia mediated by serotonin. Preclinical testing suggests that APD791 could have a unique risk-benefit profile because its anti-thrombotic activity may be less likely to cause the increased bleeding seen with anti-thrombotic agents that are members of other classes of drugs.
Serotonin 5-HT2 Receptor Antagonists
Drugs that bind to but do not activate SEROTONIN 5-HT2 RECEPTORS, thereby blocking the actions of SEROTONIN or SEROTONIN 5-HT2 RECEPTOR AGONISTS. Included under this heading are antagonists for one or more specific 5-HT2 receptor subtypes. (See all compounds classified as Serotonin 5-HT2 Receptor Antagonists.)
APD791 targets the 5-HT2A serotonin receptor, blocking the signal of serotonin, which facilitates thrombosis.
ABOUT THIS PAGE
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PharmaCompass offers a list of Temanogrel API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Temanogrel manufacturer or Temanogrel supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Temanogrel manufacturer or Temanogrel supplier.
PharmaCompass also assists you with knowing the Temanogrel API Price utilized in the formulation of products. Temanogrel API Price is not always fixed or binding as the Temanogrel Price is obtained through a variety of data sources. The Temanogrel Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.
A Temanogrel manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Temanogrel, including repackagers and relabelers. The FDA regulates Temanogrel manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Temanogrel API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Temanogrel supplier is an individual or a company that provides Temanogrel active pharmaceutical ingredient (API) or Temanogrel finished formulations upon request. The Temanogrel suppliers may include Temanogrel API manufacturers, exporters, distributors and traders.
Temanogrel Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Temanogrel GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Temanogrel GMP manufacturer or Temanogrel GMP API supplier for your needs.
A Temanogrel CoA (Certificate of Analysis) is a formal document that attests to Temanogrel's compliance with Temanogrel specifications and serves as a tool for batch-level quality control.
Temanogrel CoA mostly includes findings from lab analyses of a specific batch. For each Temanogrel CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Temanogrel may be tested according to a variety of international standards, such as European Pharmacopoeia (Temanogrel EP), Temanogrel JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Temanogrel USP).
