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ACTIVE PHARMA INGREDIENTS

12 API Suppliers, 2 USDMF, 1 EU WC, 6 KDMF, 1 NDC API, 9 Listed Suppliers, $ API Reference Price

12 API Suppliers
2 USDMF
1 EU WC
6 KDMF
1 NDC API
9 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

26 Drugs in Development

26 Drugs in Development

INTERMEDIATES

2 Intermediates Suppliers

2 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

13 FDF Dossiers, 3 FDA Orange Book, 7 Europe, 3 Listed Dossiers

13 FDF Dossiers
3 FDA Orange Book
7 Europe
3 Listed Dossiers

DIGITAL CONTENT

2 DATA COMPILATION #PharmaFlow, 2 STOCK RECAP #PipelineProspector, 74 NEWS #PharmaBuzz

media
2 DATA COMPILATION #PharmaFlow
2 STOCK RECAP #PipelineProspector
74 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

7 Finished Drug Prices, 24 Annual Reports

globalSalesInformation
7 Finished Drug Prices
24 Annual Reports

MARKET PLACE

5 APIs, 2 FDF Dossiers

marketPlace
5 APIs
2 FDF Dossiers

ANALYTICAL

1 BioAnalytical Methods

otherMethods
1 BioAnalytical Methods

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

MARKET PLACE

API

FDF

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

67,938

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: Schembl16402708

Molecular Formula

C₂₁H₂₉N₆O₅P

Molecular Weight

476.5 g/mol

InChI Key

LDEKQSIMHVQZJK-LYTUVDLCSA-N

1 2D Structure

Tenofovir Alafenamide

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

propan-2-yl (2S)-2-[[1-(6-aminopurin-9-yl)propan-2-yloxymethyl-phenoxyphosphoryl]amino]propanoate

2.1.2 InChI

InChI=1S/C21H29N6O5P/c1-14(2)31-21(28)16(4)26-33(29,32-17-8-6-5-7-9-17)13-30-15(3)10-27-12-25-18-19(22)23-11-24-20(18)27/h5-9,11-12,14-16H,10,13H2,1-4H3,(H,26,29)(H2,22,23,24)/t15?,16-,33+/m0/s1

2.1.3 InChI Key

LDEKQSIMHVQZJK-LYTUVDLCSA-N

2.1.4 Canonical SMILES

CC(C)OC(=O)C(C)NP(=O)(COC(C)CN1C=NC2=C(N=CN=C21)N)OC3=CC=CC=C3

2.1.5 Isomeric SMILES

C[C@@H](C(=O)OC(C)C)N[P@@](=O)(COC(C)CN1C=NC2=C(N=CN=C21)N)OC3=CC=CC=C3

2.2 Synonyms

2.2.1 Depositor-Supplied Synonyms

1. Schembl16402708

2.3 Create Date

2013-04-19

3 Chemical and Physical Properties

Molecular Formula	C₂₁H₂₉N₆O₅P
Molecular Weight	476.5 g/mol
XLogP3	1.9
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	12
Exact Mass	476.19370504 g/mol
Monoisotopic Mass	476.19370504 g/mol
Topological Polar Surface Area	144 Å²
Heavy Atom Count	33
Formal Charge	0
Complexity	680
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

API SUPPLIERS

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USDMF

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EU WC

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KDMF

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NDC API

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Listed Suppliers

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API Reference Price

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CRESCENZO, C\/38-39, G-BLOCK, BANDRA KURLA COMPLEX, Cont, MUMBAI","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1645986600,"product":"TENOFOVIR ALAFENAMIDE FUMARATE (C), BATC","address":"CIPLA HOUSE, PENINSULA BUSINESS,PA RK,GANPATRAO KADAM MARG,LOWER","city":"PAREL MUMBAI MAHARASHTRA,MAHARASHTR","supplier":"CIPLA","supplierCountry":"INDIA","foreign_port":"DHAKA","customer":"ONE BANK LTD","customerCountry":"BANGLADESH","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"5500","totalValueFC":"10579.4","currency":"USD","unitRateINR":396500,"date":"28-Feb-2022","totalValueINR":"793000","totalValueInUsd":"10579.4","indian_port":"BANGALORE AIR","hs_no":"29335990","bill_no":"8583209","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BANGLADESH","selfForZScoreResived":"Pharma Grade","supplierPort":"BANGALORE AIR","supplierAddress":"CIPLA HOUSE, PENINSULA BUSINESS,PA RK,GANPATRAO KADAM 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