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    Chemistry

    Click the arrow to open the dropdown
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    Also known as: 63590-64-7, Terazosine, Hytrin, Terazosina, Terazosinum, Flumarc
    Molecular Formula
    C19H25N5O4
    Molecular Weight
    387.4  g/mol
    InChI Key
    VCKUSRYTPJJLNI-UHFFFAOYSA-N
    FDA UNII
    8L5014XET7
    Terazosin
    Terazosin is a quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and hypertension. Terazosin blocks adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and the prostate.
    Terazosin is an alpha-Adrenergic Blocker. The mechanism of action of terazosin is as an Adrenergic alpha-Antagonist.
    1 2D Structure

    Terazosin

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(oxolan-2-yl)methanone
    2.1.2 InChI
    InChI=1S/C19H25N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22)
    2.1.3 InChI Key
    VCKUSRYTPJJLNI-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4CCCO4)N)OC
    2.2 Other Identifiers
    2.2.1 UNII
    8L5014XET7
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. A 45975

    2. Adecur

    3. Apo-terazosin

    4. Deflox

    5. Dysalfa

    6. Flotrin

    7. Heitrin

    8. Hytrin

    9. Hytrin Bph

    10. Hytrine

    11. Magnurol

    12. Novo-terazosin

    13. Nu-terazosin

    14. Pms-terazosin

    15. Ratio-terazosin

    16. Sutif

    17. Tazusin

    18. Terazoflo

    19. Terazosin Azu

    20. Terazosin Hexal

    21. Terazosin Hydrochloride

    22. Terazosin Hydrochloride Anhydrous

    23. Terazosin, Monohydrochloride, Dihydrate

    24. Terazosina Alter

    25. Terazosina Kern

    26. Terazosina Qualix

    27. Zayasel

    2.3.2 Depositor-Supplied Synonyms

    1. 63590-64-7

    2. Terazosine

    3. Hytrin

    4. Terazosina

    5. Terazosinum

    6. Flumarc

    7. Vasomet

    8. Terazosine [inn-french]

    9. Terazosinum [inn-latin]

    10. Terazosina [inn-spanish]

    11. Terazosabb

    12. Terazosin Hcl

    13. Terazosin (inn)

    14. 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)piperazine

    15. Chembl611

    16. [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(oxolan-2-yl)methanone

    17. Mls000069703

    18. Chebi:9445

    19. 141269-44-5

    20. Terazosin (hydrochloride)

    21. 8l5014xet7

    22. 141269-45-6

    23. Smr000058309

    24. Terazosin [inn]

    25. Terazosin [inn:ban]

    26. 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(tetrahydro-2-furoyl)piperazine

    27. 6,7-dimethoxy-2-[4-(oxolane-2-carbonyl)piperazin-1-yl]quinazolin-4-amine

    28. (4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(tetrahydrofuran-2-yl)methanone

    29. [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl](tetrahydrofuran-2-yl)methanone

    30. 6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine

    31. Abbott 45975

    32. 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]piperazine

    33. 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-{(tetnaphydro-2-furanyl)carbonyl}piperazine

    34. 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)4-[(tetrahydro-2-furanyl)carbonyl]piperazine

    35. Terazosabb (tn)

    36. 6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine Hydrochloride

    37. Terazosin A

    38. Unii-8l5014xet7

    39. Terazosinhydrochloride

    40. Terazosin [mi]

    41. 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)4-[(tetrahydro-2-furanyl)carbonyl]piperazine Hydrochloride

    42. Opera_id_1910

    43. Prestwick0_000751

    44. Prestwick1_000751

    45. Prestwick2_000751

    46. Prestwick3_000751

    47. Terazosin [vandf]

    48. Schembl6528

    49. Terazosin [who-dd]

    50. Lopac0_001138

    51. Regid_for_cid_5401

    52. Bspbio_000762

    53. Mls001201836

    54. Mls006011889

    55. Spbio_002701

    56. Bpbio1_000840

    57. Gtpl7302

    58. Dtxsid3023639

    59. Hms2090p21

    60. Hms2232n21

    61. Hms3259f04

    62. Hms3369p14

    63. Hms3371e20

    64. Hms3742i09

    65. Hy-b0371

    66. Bbl010743

    67. Bdbm50033111

    68. Stk567029

    69. Akos005266642

    70. Ccg-205212

    71. Db01162

    72. Nc00689

    73. Sdccgsbi-0051105.p002

    74. 6,7-bis(methyloxy)-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine

    75. Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)-

    76. Ncgc00016026-04

    77. Ncgc00016026-05

    78. Ncgc00016026-08

    79. Ncgc00016026-11

    80. Ncgc00025191-03

    81. Ac-11120

    82. Ls-14728

    83. Ft-0630739

    84. C07127

    85. D08569

    86. 590t647

    87. A834201

    88. L000692

    89. Q280786

    90. Brd-a22256192-003-03-7

    91. Brd-a22256192-003-14-4

    92. Z1172269406

    93. 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine

    94. 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)-piperazine

    95. 6,7-dimethoxy-2-[4-(oxolane-2-carbonyl)piperazin-1-yl]-3,4-dihydroquinazolin-4-imine

    96. 6,7-dimethoxy-2-[4-(tetrahydro-2-furanylcarbonyl)-1-piperazinyl]-4-quinazolinamine #

    97. 6,7-dimethoxy-2-{4-[(oxolan-2-yl)carbonyl]piperazin-1-yl}quinazolin-4-amine

    98. 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]-piperazinehydrochloride

    99. 1-(4-amino-6,7-dimethoxyquinazolin-2-yl)-4-[[(2rs)-2,3,4,5-tetrahydrofuran-2-yl]carbonyl]piperazine

    2.4 Create Date
    2005-03-25
    3 Chemical and Physical Properties
    Molecular Weight 387.4 g/mol
    Molecular Formula C19H25N5O4
    XLogP31.4
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count8
    Rotatable Bond Count4
    Exact Mass387.19065430 g/mol
    Monoisotopic Mass387.19065430 g/mol
    Topological Polar Surface Area103 Ų
    Heavy Atom Count28
    Formal Charge0
    Complexity544
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count1
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Indication

    Terazosin is indicated for use in treating symptomatic benign prostatic hyperplasia and hypertension.

    FDA Label

    5 Pharmacology and Biochemistry
    5.1 Pharmacology

    Terazosin is a quinazoline derivative alpha-1-selective adrenergic blocker.

    5.2 MeSH Pharmacological Classification

    Adrenergic alpha-1 Receptor Antagonists

    Drugs that bind to and block the activation of ADRENERGIC ALPHA-1 RECEPTORS. (See all compounds classified as Adrenergic alpha-1 Receptor Antagonists.)

    Urological Agents

    Drugs used in the treatment of urological conditions and diseases such as URINARY INCONTINENCE and URINARY TRACT INFECTIONS. (See all compounds classified as Urological Agents.)

    5.3 FDA Pharmacological Classification
    5.3.1 Active Moiety
    TERAZOSIN
    5.3.2 FDA UNII
    8L5014XET7
    5.3.3 Pharmacological Classes
    alpha-Adrenergic Blocker [EPC]; Adrenergic alpha-Antagonists [MoA]
    5.4 ATC Code

    G04CA03

    S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355

    G - Genito urinary system and sex hormones

    G04 - Urologicals

    G04C - Drugs used in benign prostatic hypertrophy

    G04CA - Alpha-adrenoreceptor antagonists

    G04CA03 - Terazosin

    5.5 Absorption, Distribution and Excretion

    Absorption

    Approximately 90%.

    Route of Elimination

    Approximately 10% of the oral dose is excreted unchanged in the urine and approximately 20% is excreted in the feces. 40% of the total dose is eliminated in urine and 60% of the total dose is eliminated in the feces.

    Volume of Distribution

    25L to 30L.

    Clearance

    Plasma clearance is 80mL/min and renal clearance is 10mL/min.

    5.6 Metabolism/Metabolites

    The majority of terazosin is hepatically metabolized. The metabolites recovered include 6-O-demethyl terazosin, 7-O-methyl terazosin, a piperozine derivative, and a diamine derivative.

    5.7 Biological Half-Life

    Terazosin has a mean half life 12 hours though this can be as high as 14 hours in patients over 70 years and as low as 11.4 hours in patients 20 to 39 years old.

    5.8 Mechanism of Action

    Terazosin is selective for alpha-1-adrenoceptors but not their individual subtypes. Inhibition of these alpha-1-adrenoceptors results in relaxation of smooth muscle in blood vessels and the prostate, lowering blood pressure and improving urinary flow. Smooth muscle cells accounts for roughly 40% of the volume of the prostate and so their relaxation reduces pressure on the urethra. It has also been shown that catecholamines induce factors responsible for mitogenesis and alpha-1-adrenergic receptor blockers inhibit this effect. A final long term mechanism of terazosin and other alpha-1-adrenergic receptor blockers is the induction of apoptosis of prostate cells. Treatment with terazosin enhances the expression of transforming growth factor beta-1 (TGF-beta1), which upregulates p27kip1, and the caspase cascade.

    API Reference Price

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IND. AREA CHARKOP KANDIVALI WEST Contact No:","city":"MUMBAI","supplier":"BIOINDUSTRIA L.I.M. SPA","supplierCountry":"ITALY","foreign_port":"NA","customer":"AJANTA PHARMA LIMITED","customerCountry":"INDIA","quantity":"0.50","actualQuantity":"0.5","unit":"KGS","unitRateFc":"5000","totalValueFC":"2802.8","currency":"EUR","unitRateINR":"427250","date":"19-Mar-2022","totalValueINR":"213625","totalValueInUsd":"2802.8","indian_port":"BOMBAY AIR","hs_no":"29349990","bill_no":"7925971","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"AJANTA HOUSE. 98 GOVT. IND. AREA CHARKOP KANDIVALI WEST Contact No:"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1658687400,"product":"TERAZOSIN HCL USP((BATCH NO.TZ2022\/00077 & TZ2022\/00078)","address":"98, GOVT.INDUSTRIAL AREA,","city":"MUMBAI.","supplier":"BIOINDUSTRIA L.I.M. SPA","supplierCountry":"ITALY","foreign_port":"N\/A","customer":"AJANTA PHARMA LIMITED","customerCountry":"INDIA","quantity":"14.00","actualQuantity":"14","unit":"KGS","unitRateFc":"1851.1","totalValueFC":"26383.2","currency":"USD","unitRateINR":"149850","date":"25-Jul-2022","totalValueINR":"2097900","totalValueInUsd":"26383.2","indian_port":"Dahez-SEZ","hs_no":"29349990","bill_no":"1003489","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"15067 NOVI LIGURE (AL) VA DE AMBROS IIS 2 Italy","customerAddress":"98, GOVT.INDUSTRIAL AREA,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1675621800,"product":"TERAZOSIN HYDROCHLORID DIHYDRATE","address":"LINCOLN HOUSE, B\/H.SATYAM COMPLEX SCIENCE CITY ROAD, SOLA,","city":"AHMEDABAD","supplier":"CHEMISCHE FABRIK BERG","supplierCountry":"GERMANY","foreign_port":"NA","customer":"LINCOLN PHARMACEUTICALS","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"4000","totalValueFC":"4446.1","currency":"EUR","unitRateINR":"367200","date":"06-Feb-2023","totalValueINR":"367200","totalValueInUsd":"4446.1","indian_port":"AHMEDABAD AIR","hs_no":"29349990","bill_no":"4512837","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"LINCOLN HOUSE, B\/H.SATYAM COMPLEX SCIENCE CITY ROAD, SOLA,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1676226600,"product":"TERAZOSIN HYDROCHLORIDE USP LOT\/BATCH NO. 03590000317","address":"BLOCK NO. 102 AT & POST GAVASAD,PA DRA JAMBUSAR ROAD TALUKA PADRA","city":"VADODARA,GUJARAT","supplier":"APNAR PHARMA","supplierCountry":"UNITED STATES","foreign_port":"NA","customer":"APNAR PHARMA","customerCountry":"INDIA","quantity":"40.00","actualQuantity":"40","unit":"KGS","unitRateFc":"1350","totalValueFC":"55081.5","currency":"USD","unitRateINR":"113729.5","date":"13-Feb-2023","totalValueINR":"4549181.26","totalValueInUsd":"55081.5","indian_port":"AHMEDABAD AIR","hs_no":"29349990","bill_no":"4616064","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"BLOCK NO. 102 AT & POST GAVASAD,PA DRA JAMBUSAR ROAD TALUKA PADRA"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1681324200,"product":"TERAZOSIN RELATED COMPOUND C (QTY:1 X 25 MG,VALUE:USD 838)(FOC)","address":"P.NO. 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D6 & D8, SY.NO. 234\/2,234\/3, ,235\/2 & 542\/2, IKP KNOWLEDGE PARK,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1688149800,"product":"TERAZOSIN HYDROCHLORIDE (QTY: 1 X 200MG, VALUE: USD 265) (FOC)","address":"P.NO. D6 & D8, SY.NO. 234\/2,234\/3, ,235\/2 & 542\/2, IKP KNOWLEDGE PARK,","city":"TURKAPALLY-V SHAMIRPET HYDERABAD,TE","supplier":"USP","supplierCountry":"INDIA","foreign_port":"NA","customer":"UNITED STATES PHARMACOPEIA - INDIA PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.0002","unit":"KGS","unitRateFc":"1325000","totalValueFC":"277.6","currency":"USD","unitRateINR":"114067900.4","date":"01-Jul-2023","totalValueINR":"22813.371","totalValueInUsd":"277.6","indian_port":"HYDERABAD AIR","hs_no":"29349990","bill_no":"0","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"P.NO. D6 & D8, SY.NO. 234\/2,234\/3, ,235\/2 & 542\/2, IKP KNOWLEDGE PARK,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1688149800,"product":"TERAZOSIN RELATED COMPOUND B (QTY: 1 X 0.35GMS, VALUE: USD 108.93) (FOC)","address":"P.NO. D6 & D8, SY.NO. 234\/2,234\/3, ,235\/2 & 542\/2, IKP KNOWLEDGE PARK,","city":"TURKAPALLY-V SHAMIRPET HYDERABAD,TE","supplier":"USP","supplierCountry":"INDIA","foreign_port":"NA","customer":"UNITED STATES PHARMACOPEIA - INDIA PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.00035","unit":"KGS","unitRateFc":"311228.6","totalValueFC":"114.1","currency":"USD","unitRateINR":"26793342.5","date":"01-Jul-2023","totalValueINR":"9377.914","totalValueInUsd":"114.1","indian_port":"HYDERABAD AIR","hs_no":"29349990","bill_no":"0","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"P.NO. D6 & D8, SY.NO. 234\/2,234\/3, ,235\/2 & 542\/2, IKP KNOWLEDGE PARK,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1688149800,"product":"TERAZOSIN RELATED COMPOUND B (QTY: 2 X 0.05GMS, VALUE: USD 26.45\/EACH) (FOC)","address":"P.NO. D6 & D8, SY.NO. 234\/2,234\/3, ,235\/2 & 542\/2, IKP KNOWLEDGE PARK,","city":"TURKAPALLY-V SHAMIRPET HYDERABAD,TE","supplier":"USP","supplierCountry":"INDIA","foreign_port":"NA","customer":"UNITED STATES PHARMACOPEIA - INDIA PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.0001","unit":"KGS","unitRateFc":"529000","totalValueFC":"55.4","currency":"USD","unitRateINR":"45541099.6","date":"01-Jul-2023","totalValueINR":"4554.011","totalValueInUsd":"55.4","indian_port":"HYDERABAD AIR","hs_no":"29349990","bill_no":"0","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"P.NO. D6 & D8, SY.NO. 234\/2,234\/3, ,235\/2 & 542\/2, IKP KNOWLEDGE PARK,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1691346600,"product":"TERAZOSIN HYDROCHLORIDE DIHYDRATE BATCH N TZ 2023\/00079","address":"NA","city":"NA","supplier":"BIOINDUSTRIA LABORATORIO ITALIANO MEDICINALI SPA","supplierCountry":"ITALY","foreign_port":"NA","customer":"ORBION PHARMACEUTICALS PRIVATE LIMITED","customerCountry":"INDIA","quantity":"35.00","actualQuantity":"35","unit":"KGS","unitRateFc":"1500","totalValueFC":"58254.4","currency":"EUR","unitRateINR":"136495","date":"07-Aug-2023","totalValueINR":"4825579.264","totalValueInUsd":"58254.4","indian_port":"CHENNAI AIR","hs_no":"29349990","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"NA"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1691346600,"product":"TERAZOSIN HYDROCHLORIDE DIHYDRATE BATCH N TZ 2023\/00080","address":"NA","city":"NA","supplier":"BIOINDUSTRIA LABORATORIO ITALIANO MEDICINALI SPA","supplierCountry":"ITALY","foreign_port":"NA","customer":"ORBION PHARMACEUTICALS PRIVATE LIMITED","customerCountry":"INDIA","quantity":"55.00","actualQuantity":"55","unit":"KGS","unitRateFc":"1500","totalValueFC":"91542.6","currency":"EUR","unitRateINR":"136495","date":"07-Aug-2023","totalValueINR":"7583053.368","totalValueInUsd":"91542.6","indian_port":"CHENNAI AIR","hs_no":"29349990","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"NA"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1691346600,"product":"TERAZOSIN HYDROCHLORIDE DIHYDRATE BATCH N TZ 2023\/00080","address":"NA","city":"NA","supplier":"BIOINDUSTRIA LABORATORIO ITALIANO MEDICINALI SPA","supplierCountry":"ITALY","foreign_port":"NA","customer":"ORBION PHARMACEUTICALS PRIVATE LIMITED","customerCountry":"INDIA","quantity":"60.00","actualQuantity":"60","unit":"KGS","unitRateFc":"1500","totalValueFC":"99864.7","currency":"EUR","unitRateINR":"136495","date":"07-Aug-2023","totalValueINR":"8272422.312","totalValueInUsd":"99864.7","indian_port":"CHENNAI AIR","hs_no":"29349990","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"NA"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1700850600,"product":"TERAZOSIN HCL ANHYDROUS","address":"BLOCK NO. 102 AT & POST GAVASAD,PA","city":"VADODARA,GUJARAT","supplier":"TAPI TECHNOLOGY & API SERVICES","supplierCountry":"ITALY","foreign_port":"MILAN - MALPENSA","customer":"APNAR PHARMA","customerCountry":"INDIA","quantity":"125.00","actualQuantity":"125","unit":"KGS","unitRateFc":"1300","totalValueFC":"172652.1","currency":"USD","unitRateINR":"115015.2","date":"25-Nov-2023","totalValueINR":"14376895","totalValueInUsd":"172652.1","indian_port":"Ahmedabad Air","hs_no":"29349990","bill_no":"8937439","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"MILAN - MALPENSA","supplierAddress":"PIET HEIN BUILDINGPIET HEINKADE 1071019 GM AMSTERDAM NL","customerAddress":"BLOCK NO. 102 AT & POST GAVASAD,PA"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1720377000,"product":"TERAZOSIN HCL USP(BATCH NO.TZ2024\/00082)","address":"98, GOVT.INDUSTRIAL AREA,","city":"MUMBAI.","supplier":"XXOINXXSTRXX L.XXM.,XXITAXX","supplierCountry":"ITALY","foreign_port":"SEGRATE","customer":"AJANTA PHARMA LIMITED","customerCountry":"INDIA","quantity":"60.00","actualQuantity":"60","unit":"KGS","unitRateFc":"1850.2","totalValueFC":"111955.7","currency":"USD","unitRateINR":"155975","date":"08-Jul-2024","totalValueINR":"9358500","totalValueInUsd":"111955.7","indian_port":"Dahez-SEZ","hs_no":"29349990","bill_no":"1003334","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"SEGRATE","supplierAddress":"N\/A","customerAddress":"98, GOVT.INDUSTRIAL AREA,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1726165800,"product":"TERAZOSIN HCL USP(BATCH NO.TZ2024\/00084)","address":"98, GOVT.INDUSTRIAL AREA,","city":"MUMBAI.","supplier":"BIOINDUSTRIA L.I.M. SPA","supplierCountry":"ITALY","foreign_port":"SEGRATE","customer":"AJANTA PHARMA LIMITED","customerCountry":"INDIA","quantity":"36.00","actualQuantity":"36","unit":"KGS","unitRateFc":"1913","totalValueFC":"69772.5","currency":"USD","unitRateINR":"162417.3","date":"13-Sep-2024","totalValueINR":"5847023","totalValueInUsd":"69772.5","indian_port":"Dahez-SEZ","hs_no":"29349990","bill_no":"1004564","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"SEGRATE","supplierAddress":"BIOINDUSTRIA LABORATORIO ITALIANO MEDICINAL S.P.A.VIA DE AMBROSIIS,2\/ 4\/6,15067 NOVI LIGUREAL ITALY","customerAddress":"98, GOVT.INDUSTRIAL AREA,"}]
    29-Jan-2021
    04-Dec-2024
    KGS
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    Average Price (USD/KGS)

    Number of Transactions

    Total Quantity (KGS)

    Total Value (USD)

    Quantity (KGS) & Unit rate (USD/KGS) over time

    API Imports and Exports

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    INTERMEDIATE SUPPLIERS

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    01

    PMC Isochem

    France
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    Virtual BoothPMC Isochem is your partner for smart CDMOs of Intermediates, APIs, & excipients & a catalog of Intermediates & Generic APIs.

    4-Amino-2-chloro-6,7-dimethoxyquinazoline

    CAS Number : 23680-84-4

    End Use API : Terazosin

    About The Company : PMC Isochem is a CDMO company acquired by PMC International in 2017. It manufactures cGMP intermediates, active pharmaceutical ingredients and functional excipi...

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    02

    Synthokem Labs

    India
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    Virtual BoothSynthokem Labs specializes in producing APIs and intermediates for the global pharma industry.

    Tetrahydro-2-Furoic Acid

    CAS Number : 16874-33-2

    End Use API : Terazosin

    About The Company : Synthokem Labs Pvt Ltd is a privately owned company established in 1978, specializing in the production of Active Pharmaceutical Ingredients and Drug Intermedia...

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    03

    Almelo

    India
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    Almelo

    India
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    4-Amino-2-Chloro-6,7- Dimethoxy Quinazoline

    CAS Number : CAS-23680-84-4

    End Use API : Terazosin

    About The Company : Almelo are the industry leaders in manufacturing advanced intermediates, Active Pharmaceutical Ingredients (APIs) and specialty fine chemicals. With a diverse p...

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    04

    Almelo

    India
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    Almelo

    India
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    6,7-Dimethoxy-2,4- Quinazolinedione

    CAS Number : CAS-28888-44-0

    End Use API : Terazosin

    About The Company : Almelo are the industry leaders in manufacturing advanced intermediates, Active Pharmaceutical Ingredients (APIs) and specialty fine chemicals. With a diverse p...

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    05

    Almelo

    India
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    Almelo

    India
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    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

    1 - (2-Tetrahydrofuroyl) – Piperazine

    CAS Number : CAS-63074-07-7

    End Use API : Terazosin

    About The Company : Almelo are the industry leaders in manufacturing advanced intermediates, Active Pharmaceutical Ingredients (APIs) and specialty fine chemicals. With a diverse p...

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    06

    Shree Ganesh Remedies

    India
    Biotech Digital Meet
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    Shree Ganesh Remedies

    India
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    2-Furoyl Chloride

    CAS Number : 527-69-5

    End Use API : Terazosin

    About The Company : Shree Ganesh Remedies is established Since 1995 with an aim to manufacture, supply and export best quality of Pharmaceutical-intermediates, Bulk drugs and Speci...

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    07

    Shree Ganesh Remedies

    India
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    Shree Ganesh Remedies

    India
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    2-Furoic Acid

    CAS Number : 88-14-2

    End Use API : Terazosin

    About The Company : Shree Ganesh Remedies is established Since 1995 with an aim to manufacture, supply and export best quality of Pharmaceutical-intermediates, Bulk drugs and Speci...

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    08

    Shree Ganesh Remedies

    India
    Biotech Digital Meet
    Not Confirmed
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    Shree Ganesh Remedies

    India
    Biotech Digital Meet
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    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

    Tetrahydro-2-furoic acid

    CAS Number : 16874-33-2

    End Use API : Terazosin

    About The Company : Shree Ganesh Remedies is established Since 1995 with an aim to manufacture, supply and export best quality of Pharmaceutical-intermediates, Bulk drugs and Speci...

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    09

    Sigmak Lifesciences

    India
    Biotech Digital Meet
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    Sigmak Lifesciences

    India
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    2,4-Dichloro-6,7-dimethoxyquinazoline

    CAS Number : 27631-29-4

    End Use API : Terazosin

    About The Company : Sigmak Lifesciences is a leading contract manufacturer, merchant exporter, & distributor of pharmaceutical APIs & Fine Chemicals. We excel in Contract Manufactu...

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    10

    Sigmak Lifesciences

    India
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    Sigmak Lifesciences

    India
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    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

    4-Amino-2-chloro-6,7-dimethoxy quinazoline

    CAS Number : 23680-84-4

    End Use API : Terazosin

    About The Company : Sigmak Lifesciences is a leading contract manufacturer, merchant exporter, & distributor of pharmaceutical APIs & Fine Chemicals. We excel in Contract Manufactu...

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    ABOUT THIS PAGE

    Looking for 63590-64-7 / Terazosin API manufacturers, exporters & distributors?

    Terazosin manufacturers, exporters & distributors 1

    58

    PharmaCompass offers a list of Terazosin API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Terazosin manufacturer or Terazosin supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Terazosin manufacturer or Terazosin supplier.

    PharmaCompass also assists you with knowing the Terazosin API Price utilized in the formulation of products. Terazosin API Price is not always fixed or binding as the Terazosin Price is obtained through a variety of data sources. The Terazosin Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Terazosin

    Synonyms

    63590-64-7, Terazosine, Hytrin, Terazosina, Terazosinum, Flumarc

    Cas Number

    63590-64-7

    Unique Ingredient Identifier (UNII)

    8L5014XET7

    About Terazosin

    Terazosin is a quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and hypertension. Terazosin blocks adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and the prostate.

    Terazosin Manufacturers

    A Terazosin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Terazosin, including repackagers and relabelers. The FDA regulates Terazosin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Terazosin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Terazosin manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Terazosin Suppliers

    A Terazosin supplier is an individual or a company that provides Terazosin active pharmaceutical ingredient (API) or Terazosin finished formulations upon request. The Terazosin suppliers may include Terazosin API manufacturers, exporters, distributors and traders.

    click here to find a list of Terazosin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Terazosin NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Terazosin as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Terazosin API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Terazosin as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Terazosin and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Terazosin NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Terazosin suppliers with NDC on PharmaCompass.

    Terazosin GMP

    Terazosin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Terazosin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Terazosin GMP manufacturer or Terazosin GMP API supplier for your needs.

    Terazosin CoA

    A Terazosin CoA (Certificate of Analysis) is a formal document that attests to Terazosin's compliance with Terazosin specifications and serves as a tool for batch-level quality control.

    Terazosin CoA mostly includes findings from lab analyses of a specific batch. For each Terazosin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Terazosin may be tested according to a variety of international standards, such as European Pharmacopoeia (Terazosin EP), Terazosin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Terazosin USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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