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CHSD Tetracaine Hydrochloride

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Nuray Tetracaine HCl

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xyz-pharma-m-2025-01-06

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ACTIVE PHARMA INGREDIENTS

21 API Suppliers, 6 USDMF, 2 CEP/COS, 1 JDMF, 3 EU WC, 12 NDC API, 16 Listed Suppliers, $ API Reference Price

21 API Suppliers
6 USDMF
2 CEP/COS
1 JDMF
3 EU WC
12 NDC API
16 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

1 Drugs in Development

1 Drugs in Development

FINISHED DOSAGE FORMULATIONS

16 FDF Dossiers, 3 FDA Orange Book, 1 Europe, 7 Canada, 4 South Africa, 1 Listed Dossiers

16 FDF Dossiers
3 FDA Orange Book
1 Europe
7 Canada
4 South Africa
1 Listed Dossiers

RELATED EXCIPIENT COMPANIES

2 Seqens, 6 DKSH, 2 Faran Shimi Pharmaceutical, 4 Gangwal Healthcare, 3 Nanjing Well Pharmaceutical, 1 ACG Worldwide, 13 Actylis, 1 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 11 BASF, 10 Corel Pharma Chem, 2 DFE Pharma, 5 Finar, 3 Gangwal Chemicals, 4 Ideal Cures Pvt Ltd, 26 Kerry, 3 Kima Chemical, 6 Lonza Capsugel, 6 Microlex e.U, 2 Nomisma Healthcare, 1 Novo Excipients, 3 Pluviaendo, 1 Qianhao Chemical (Hebei) Co., Ltd, 1 Qualicaps, 4 Roquette, 6 Seppic, 1 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 2 Sigachi Industries, 2 The Dow Chemical Company, 1 Valens Pharmachem

EXCIPIENTS BY APPLICATIONS

42 Coating Systems & Additives, 25 Fillers, Diluents & Binders, 22 Controlled & Modified Release, 21 Topical, 14 Parenteral, 12 Film Formers & Plasticizers, 10 Solubilizers, 10 Direct Compression, 10 Thickeners and Stabilizers, 8 Granulation, 5 Empty Capsules, 5 Co-Processed Excipients, 4 Vegetarian Capsules, 4 Rheology Modifiers, 3 API Stability Enhancers, 3 Taste Masking, 3 Lubricants & Glidants, 2 Coloring Agents, 2 Emulsifying Agents, 1 Disintegrants & Superdisintegrants, 1 Chewable & Orodispersible Aids

DIGITAL CONTENT

1 DATA COMPILATION #PharmaFlow, 3 NEWS #PharmaBuzz

media
1 DATA COMPILATION #PharmaFlow
3 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions

globalSalesInformation
1 US Medicaid Prescriptions

MARKET PLACE

4 APIs

marketPlace
4 APIs

PATENTS & EXCLUSIVITIES

2 US Patents

patents
2 US Patents

REF. STANDARDS & IMPURITIES

3 EDQM , 1 USP , 1 Others

otherSolutions
3 EDQM
1 USP
1 Others

CHSD Tetracaine Hydrochloride

Synopsis

ACTIVE PHARMA INGREDIENTS

21

API Suppliers

6

USDMF

2

CEP/COS

CEP/COS Certifications

1

JDMF

3

EU WC

0

KDMF

12

NDC API

0

VMF

16

Listed Suppliers

API REF. PRICE (USD/KG)

$

$ 172

MARKET PLACE

4

API

0

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

16

FDF Dossiers

3

FDA Orange Book

FDA (Orange Book)

1

Europe

7

Canada

0

Australia

4

South Africa

1

Listed Dossiers

1DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

3

EDQM

1

USP

0

JP

1

Others

PATENTS & EXCLUSIVITIES

2

US Patents

0

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

1

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

3

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

5,762

Annual Reports (USD Million)

NA

Finished Drug Prices

NA

132 RELATED EXCIPIENT COMPANIES

207EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 136-47-0, Tetracaine hcl, Butethanol, Amethocaine hydrochloride, Pantocaine, Curtacain

Molecular Formula

C₁₅H₂₅ClN₂O₂

Molecular Weight

300.82 g/mol

InChI Key

PPWHTZKZQNXVAE-UHFFFAOYSA-N

FDA UNII

5NF5D4OPCI

Tetracaine Hydrochloride

A potent local anesthetic of the ester type used for surface and spinal anesthesia.

1 2D Structure

Tetracaine Hydrochloride

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

2-(dimethylamino)ethyl 4-(butylamino)benzoate;hydrochloride

2.1.2 InChI

InChI=1S/C15H24N2O2.ClH/c1-4-5-10-16-14-8-6-13(7-9-14)15(18)19-12-11-17(2)3;/h6-9,16H,4-5,10-12H2,1-3H3;1H

2.1.3 InChI Key

PPWHTZKZQNXVAE-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CCCCNC1=CC=C(C=C1)C(=O)OCCN(C)C.Cl

2.2 Other Identifiers

2.2.1 UNII

5NF5D4OPCI

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Amethocaine

2. Ametop

3. Dicaine

4. Hydrochloride, Tetrracaine

5. Pantocaine

6. Pontocaine

7. Tetracaine

8. Tetracaine Monohydrochloride

9. Tetrakain

10. Tetrracaine Hydrochloride

2.3.2 Depositor-Supplied Synonyms

1. 136-47-0

2. Tetracaine Hcl

3. Butethanol

4. Amethocaine Hydrochloride

5. Pantocaine

6. Curtacain

7. Menonasal

8. Anethaine

9. Dicainum

10. Tetracaine, Hcl

11. Tetracaine (hydrochloride)

12. Butylocaine

13. 2-(dimethylamino)ethyl 4-(butylamino)benzoate Hydrochloride

14. Tetocaine

15. Tetraca

16. Tetracainehydrochloride

17. 5nf5d4opci

18. 2-(dimethylamino)ethyl P-(butylamino)benzoate Monohydrochloride

19. Nsc-757337

20. 4-(butylamino)benzoic Acid 2-(dimethylamino)ethyl Ester Hydrochloride

21. Benzoic Acid, 4-(butylamino)-, 2-(dimethylamino)ethyl Ester, Monohydrochloride

22. Mls000069780

23. Tetracaine Hydrochloride (pontocaine)

24. Anethain

25. Decicain

26. Decicaine

27. Dessicain

28. Intercaine

29. Leocaine

30. Pantocain

31. Smr000058522

32. Tonexol

33. Anacel

34. Gingicain M

35. Dsstox_cid_22448

36. Dsstox_rid_80027

37. Dsstox_gsid_42448

38. Tetracainium Chloridum

39. Tetracaine Chlorhydrate

40. 2-(dimethylamino)ethyl 4-(butylamino)benzoate;hydrochloride

41. Viractin

42. Tetracaine Monohydrochloride

43. Amethocaine Monohydrochloride

44. Sr-01000075240

45. Ncgc00016049-02

46. Cas-136-47-0

47. Einecs 205-248-5

48. Unii-5nf5d4opci

49. Exactacain

50. Amethocalne Hcl

51. Tetracaine Hydrochloride [usp:jan]

52. Mfcd00038912

53. P-butylaminobenzoyl-2-dimethylaminoethanol Hydrochloride

54. 2-dimethylaminoethanol 4-n-butylaminobenzoate Hydrochloride

55. Pontocaine Hydrochloride

56. 2-(dimethylamino)ethyl P-(butylamino)benzoate Hydrochloride

57. Tetracaini Hydrochloridum

58. Opera_id_1220

59. P-(butylamino)benzoic Acid, 2-(dimethylamino)ethyl Ester, Hydrochloride

60. Dicainum [who-ip]

61. Schembl24370

62. Mls002222164

63. Protocaine Hydrochloride (tn)

64. Spectrum1500564

65. 4-butylaminobenzoic Acid Dimethylaminoethyl Ester Hcl

66. Chebi:9469

67. Chembl1255654

68. Dtxsid6042448

69. Tetracaine For System Suitability

70. Tetracaine Hydrochloride, >=99%

71. Hms1569d04

72. Hms1921c17

73. Pharmakon1600-01500564

74. Act04762

75. Bcp26339

76. Hy-b0473

77. Tox21_110290

78. Tox21_501211

79. Ac-774

80. Ccg-39266

81. Nsc757337

82. S2573

83. Tetracaine Hydrochloride [mi]

84. Tetracaine Hydrochloride (jp17/usp)

85. Tetracaine Hydrochloride [jan]

86. Akos015888160

87. Tox21_110290_1

88. Ks-5059

89. Lp01211

90. Nsc 757337

91. Benzoic Acid, P-(butylamino)-, 2-(dimethylamino)ethyl Ester, Monohydrochloride

92. Tetracaine Hydrochloride [mart.]

93. Tetracaine Hydrochloride [vandf]

94. Ncgc00016049-07

95. Ncgc00094458-01

96. Ncgc00094458-02

97. Ncgc00094458-03

98. Ncgc00094458-04

99. Ncgc00094458-05

100. Ncgc00261896-01

101. Tetracaine Hydrochloride [usp-rs]

102. Tetracaine Hydrochloride [who-dd]

103. Tetracaine Hydrochloride [who-ip]

104. 53762-93-9

105. Amethocaine Hydrochloride [who-ip]

106. Db-042341

107. Eu-0101211

108. Ft-0603346

109. Ft-0674941

110. Sw196411-3

111. T1688

112. Tetracaine Hydrochloride [green Book]

113. Tetracaine Hydrochloride [orange Book]

114. D00741

115. T 7508

116. Tetracaine Hydrochloride [ep Monograph]

117. Tetracaine Hydrochloride [usp Monograph]

118. Tetracaini Hydrochloridum [who-ip Latin]

119. 136t470

120. A807078

121. Kovanaze Component Tetracaine Hydrochloride

122. Tetracaine Hydrochloride, Sigma Reference Standard

123. Q-201806

124. Sr-01000075240-1

125. Sr-01000075240-6

126. Q27262597

127. Tetracaine Hydrochloride Component Of Kovanaze

128. Tetracaine Hydrochloride, Meets Usp Testing Specifications

129. Tetracaine Hydrochloride 1.0 Mg/ml In Acetonitrile (as Free Base)

130. Tetracaine Hydrochloride, European Pharmacopoeia (ep) Reference Standard

131. Benzoic Acid, 4-(butylamino)-, 2-(dimethylamino)ethyl Ester,monohydrochloride

132. Tetracaine For System Suitability, European Pharmacopoeia (ep) Reference Standard

133. Tetracaine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

134. Tetracaine Hydrochloride, United States Pharmacopeia (usp) Reference Standard

2.4 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₁₅H₂₅ClN₂O₂
Molecular Weight	300.82 g/mol
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	9
Exact Mass	300.1604557 g/mol
Monoisotopic Mass	300.1604557 g/mol
Topological Polar Surface Area	41.6 Å²
Heavy Atom Count	20
Formal Charge	0
Complexity	249
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Anesthetics, Local

Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate. (See all compounds classified as Anesthetics, Local.)

4.2 FDA Pharmacological Classification

4.2.1 Pharmacological Classes

Esters [CS]; Local Anesthesia [PE]; Ester Local Anesthetic [EPC]

API SUPPLIERS

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CEP/COS

01

SIEGFRIED EVIONNAZ SA Evionnaz CH

Switzerland

BIO Partnering at JPM

Not Confirmed

02

VENKATA NARAYANA ACTIVE INGREDIENTS...

India

BIO Partnering at JPM

Not Confirmed

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JDMF

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EU WC

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API Reference Price

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Number of Transactions

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Quantity (KGS) & Unit rate (USD/KGS) over time

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Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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ABOUT THIS PAGE

Tetracaine Hydrochloride Manufacturers

A Tetracaine Hydrochloride manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Tetracaine Hydrochloride, including repackagers and relabelers. The FDA regulates Tetracaine Hydrochloride manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Tetracaine Hydrochloride API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Tetracaine Hydrochloride manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Tetracaine Hydrochloride Suppliers

A Tetracaine Hydrochloride supplier is an individual or a company that provides Tetracaine Hydrochloride active pharmaceutical ingredient (API) or Tetracaine Hydrochloride finished formulations upon request. The Tetracaine Hydrochloride suppliers may include Tetracaine Hydrochloride API manufacturers, exporters, distributors and traders.

click here to find a list of Tetracaine Hydrochloride suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Tetracaine Hydrochloride USDMF

A Tetracaine Hydrochloride DMF (Drug Master File) is a document detailing the whole manufacturing process of Tetracaine Hydrochloride active pharmaceutical ingredient (API) in detail. Different forms of Tetracaine Hydrochloride DMFs exist exist since differing nations have different regulations, such as Tetracaine Hydrochloride USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Tetracaine Hydrochloride DMF submitted to regulatory agencies in the US is known as a USDMF. Tetracaine Hydrochloride USDMF includes data on Tetracaine Hydrochloride's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Tetracaine Hydrochloride USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Tetracaine Hydrochloride suppliers with USDMF on PharmaCompass.

Tetracaine Hydrochloride JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Tetracaine Hydrochloride Drug Master File in Japan (Tetracaine Hydrochloride JDMF) empowers Tetracaine Hydrochloride API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Tetracaine Hydrochloride JDMF during the approval evaluation for pharmaceutical products. At the time of Tetracaine Hydrochloride JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Tetracaine Hydrochloride suppliers with JDMF on PharmaCompass.

Tetracaine Hydrochloride CEP

A Tetracaine Hydrochloride CEP of the European Pharmacopoeia monograph is often referred to as a Tetracaine Hydrochloride Certificate of Suitability (COS). The purpose of a Tetracaine Hydrochloride CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Tetracaine Hydrochloride EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Tetracaine Hydrochloride to their clients by showing that a Tetracaine Hydrochloride CEP has been issued for it. The manufacturer submits a Tetracaine Hydrochloride CEP (COS) as part of the market authorization procedure, and it takes on the role of a Tetracaine Hydrochloride CEP holder for the record. Additionally, the data presented in the Tetracaine Hydrochloride CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Tetracaine Hydrochloride DMF.

A Tetracaine Hydrochloride CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Tetracaine Hydrochloride CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Tetracaine Hydrochloride suppliers with CEP (COS) on PharmaCompass.

Tetracaine Hydrochloride WC

A Tetracaine Hydrochloride written confirmation (Tetracaine Hydrochloride WC) is an official document issued by a regulatory agency to a Tetracaine Hydrochloride manufacturer, verifying that the manufacturing facility of a Tetracaine Hydrochloride active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Tetracaine Hydrochloride APIs or Tetracaine Hydrochloride finished pharmaceutical products to another nation, regulatory agencies frequently require a Tetracaine Hydrochloride WC (written confirmation) as part of the regulatory process.

click here to find a list of Tetracaine Hydrochloride suppliers with Written Confirmation (WC) on PharmaCompass.

Tetracaine Hydrochloride NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Tetracaine Hydrochloride as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Tetracaine Hydrochloride API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Tetracaine Hydrochloride as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Tetracaine Hydrochloride and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Tetracaine Hydrochloride NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Tetracaine Hydrochloride suppliers with NDC on PharmaCompass.

Tetracaine Hydrochloride GMP

Tetracaine Hydrochloride Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Tetracaine Hydrochloride GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Tetracaine Hydrochloride GMP manufacturer or Tetracaine Hydrochloride GMP API supplier for your needs.

Tetracaine Hydrochloride CoA

A Tetracaine Hydrochloride CoA (Certificate of Analysis) is a formal document that attests to Tetracaine Hydrochloride's compliance with Tetracaine Hydrochloride specifications and serves as a tool for batch-level quality control.

Tetracaine Hydrochloride CoA mostly includes findings from lab analyses of a specific batch. For each Tetracaine Hydrochloride CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Tetracaine Hydrochloride may be tested according to a variety of international standards, such as European Pharmacopoeia (Tetracaine Hydrochloride EP), Tetracaine Hydrochloride JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Tetracaine Hydrochloride USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.

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