Find Tetrahydrocannabivarin manufacturers, exporters & distributors on PharmaCompass

Tetrahydrocannabivarin

Interquim comes from an international group of 50 companies active in the pharma, hospital, diagnostics, fine chemicals & feed sectors.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

DEVELOPMENTS

3 Drugs in Development

3 Drugs in Development

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

3DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: 31262-37-0, Delta9-tetrahydrocannabivarin, Thcv, Thc-v, .delta.9-tetrahydrocannabivarin, (6ar,10ar)-6,6,9-trimethyl-3-propyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol

Molecular Formula

C₁₉H₂₆O₂

Molecular Weight

286.4 g/mol

InChI Key

ZROLHBHDLIHEMS-HUUCEWRRSA-N

FDA UNII

I5YE3I47D8

tetrahydrocannabivarin is a natural product found in Cannabis sativa with data available.

1 2D Structure

Tetrahydrocannabivarin

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(6aR,10aR)-6,6,9-trimethyl-3-propyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol

2.1.2 InChI

InChI=1S/C19H26O2/c1-5-6-13-10-16(20)18-14-9-12(2)7-8-15(14)19(3,4)21-17(18)11-13/h9-11,14-15,20H,5-8H2,1-4H3/t14-,15-/m1/s1

2.1.3 InChI Key

ZROLHBHDLIHEMS-HUUCEWRRSA-N

2.1.4 Canonical SMILES

CCCC1=CC(=C2C3C=C(CCC3C(OC2=C1)(C)C)C)O

2.1.5 Isomeric SMILES

CCCC1=CC(=C2[C@@H]3C=C(CC[C@H]3C(OC2=C1)(C)C)C)O

2.2 Other Identifiers

2.2.1 UNII

I5YE3I47D8

2.3 Synonyms

2.3.1 Depositor-Supplied Synonyms

1. 31262-37-0

2. Delta9-tetrahydrocannabivarin

3. Thcv

4. Thc-v

5. .delta.9-tetrahydrocannabivarin

6. (6ar,10ar)-6,6,9-trimethyl-3-propyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol

7. Gwp42004

8. Gwp-42004

9. I5ye3i47d8

10. O-4394

11. Cannabivarol, .delta.9-tetrahydro-

12. (-)-.delta.9-trans-tetrahydrocannabivarin

13. 6h-dibenzo(b,d)pyran-1-ol, 6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-propyl-, (6ar-trans)-

14. 6h-dibenzo[b,d]pyran-1-ol, 6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-propyl-, (6ar-trans)-

15. Unii-i5ye3i47d8

16. 6h-dibenzo(b,d)pyran-1-ol, 6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-propyl-, (6ar,10ar)-

17. 6h-dibenzo[b,d]pyran-1-ol, 6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-propyl-, (6ar,10ar)-

18. Delta9-thcv

19. .delta.9-tetrahydrocannabivarol

20. Gtpl6418

21. Schembl6856739

22. Chembl2387541

23. .delta.1-tetrahydrocannabidivarol

24. Dtxsid10893920

25. 6h-dibenzo(b,d)pyran-1-ol, 6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-propyl-

26. Zinc5649505

27. Bdbm50511105

28. Hy-u00342

29. .delta.9-trans-tetrahydrocannabivarin

30. Cannabidivarol, .delta.1-tetrahydro-

31. Cs-7377

32. Db11755

33. 6h-dibenzo[b,d]pyran-1-ol, 6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-propyl-, (-)-

34. Delta9-tetrahydrocannabivarin (thcv) 10 Microg/ml In Methanol

35. Delta9-tetrahydrocannabivarin (thcv) 100 Ug/ml In Methanol

36. Delta9-tetrahydrocannabivarin (thcv) 1000 Ug/ml In Methanol

37. Delta9-tetrahydrocannabivarin (thcv) 250 Microg/ml In Acetonitrile

38. (6ar,10ar)-6,6,9-trimethyl-3-propyl-6h,6ah,7h,8h,10ah-benzo[c]isochromen-1-ol

39. 6,6,9-trimethyl-3-propyl-6a,7,8,10a-tetrahydro-6h-benzo[c]chromen-1-ol-, (6ar-trans)-

2.4 Create Date

2005-08-08

3 Chemical and Physical Properties

Molecular Formula	C₁₉H₂₆O₂
Molecular Weight	286.4 g/mol
XLogP3	5.9
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	2
Exact Mass	286.193280068 g/mol
Monoisotopic Mass	286.193280068 g/mol
Topological Polar Surface Area	29.5 Å²
Heavy Atom Count	21
Formal Charge	0
Complexity	412
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Drug Indication

THCV does not currently have any FDA, Health Canada, or EMA approved indications.

5 Pharmacology and Biochemistry

5.1 Pharmacology

Compared to THC which demonstrates its effects through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid-2 (CB2R) receptors, THCV acts as a CB1 antagonist and a partial agonist of CB2. Further evidence has also shown that THCV acts as an agonist of GPR55 and l--lysophosphatidylinositol (LPI). Beyond the endocannabinoid system, THCV has also been reported to activate 5HT1A receptors to produce an antipsychotic effect that has therapeutic potential for ameliorating some of the negative, cognitive and positive symptoms of schizophrenia. Furthermore, THCV interacts with different transient receptor potential (TRP) channels including TRPV1, which may contribute to the analgesic, anti-inflammatory and anti-cancer effects of cannabinoids and Cannabis extracts.

Drugs in Development