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Chemistry

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Also known as: Myolastan, Musaril, Clinoxan, 10379-14-3, Cb 4261, Ro 06-6657
Molecular Formula
C16H17ClN2O
Molecular Weight
288.77  g/mol
InChI Key
IQWYAQCHYZHJOS-UHFFFAOYSA-N
FDA UNII
FO92091VP8

Tetrazepam
1 2D Structure

Tetrazepam

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
7-chloro-5-(cyclohexen-1-yl)-1-methyl-3H-1,4-benzodiazepin-2-one
2.1.2 InChI
InChI=1S/C16H17ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h5,7-9H,2-4,6,10H2,1H3
2.1.3 InChI Key
IQWYAQCHYZHJOS-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CN1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=CCCCC3
2.2 Other Identifiers
2.2.1 UNII
FO92091VP8
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 4621 Cb

2. Mobiforton

3. Mtw-tetrazepam

4. Musapam

5. Musaril

6. Myolastan

7. Myospasmal

8. Panos

9. Rilex

10. Tethexal

11. Tetra-saar

12. Tetramdura

13. Tetrarelax

14. Tetrazep 1a Pharma

15. Tetrazep Abz

16. Tetrazep Von Ct

2.3.2 Depositor-Supplied Synonyms

1. Myolastan

2. Musaril

3. Clinoxan

4. 10379-14-3

5. Cb 4261

6. Ro 06-6657

7. 4261 Cb

8. 7-chloro-5-(cyclohexen-1-yl)-1,3-dihydro-1-methyl-2h-1,4-benzodiazepin-2-one

9. 2h-1,4-benzodiazepin-2-one, 7-chloro-5-(1-cyclohexen-1-yl)-1,3-dihydro-1-methyl-

10. Fo92091vp8

11. Tetrazepam (inn)

12. 7-chloro-5-(1-cyclohexenyl)-1-methyl-2-oxo-2,3-dihydro-1h-(1,4)-benzo(f)diazepine

13. Cb-4261

14. Tetrazepam [inn]

15. 7-chloro-5-(cyclohexen-1-yl)-1-methyl-3h-1,4-benzodiazepin-2-one

16. Tetrazepamum

17. Tetrazepamum [inn-latin]

18. Tetrazepam [inn:ban:dcf]

19. Einecs 233-837-7

20. Brn 0890548

21. Unii-fo92091vp8

22. Dea No. 2886

23. Myolastan (tn)

24. Tetrazepam [mi]

25. Tetrazepam [mart.]

26. Tetrazepam [who-dd]

27. 5-24-04-00064 (beilstein Handbook Reference)

28. Schembl157998

29. Zinc2144

30. Chembl2105527

31. Dtxsid00146058

32. Tetrazepam [ep Monograph]

33. Chebi:135198

34. Tetrazepam 0.1 Mg/ml In Methanol

35. Cs-6656

36. Db13324

37. 7-chloro-5-(1-cyclohexen-1- Yl)-1,3-dihydro-1-methyl-2h-1,4-benzodiazepin-2-one

38. Hy-101615

39. D07277

40. Q421104

41. 7-chloro-5-(1-cyclohexen-1-yl)-1-methyl-1,3-dihydro-2h-1,4-benzodiazepin-2-one #

42. 7-chloro-5-(cyclohex-1-en-1-yl)-1-methyl-1,3-dihydro-2h-benzo[e][1,4]diazepin-2-one

43. 7-chloro-5-(cyclohex-1-en-1-yl)-1-methyl-2,3-dihydro-1h-1,4-benzodiazepin-2-one

2.4 Create Date
2005-03-27
3 Chemical and Physical Properties
Molecular Weight 288.77 g/mol
Molecular Formula C16H17ClN2O
XLogP33.2
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass288.1029409 g/mol
Monoisotopic Mass288.1029409 g/mol
Topological Polar Surface Area32.7 Ų
Heavy Atom Count20
Formal Charge0
Complexity457
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Muscle Relaxants, Central

A heterogeneous group of drugs used to produce muscle relaxation, excepting the neuromuscular blocking agents. They have their primary clinical and therapeutic uses in the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. They have been used also for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in MULTIPLE SCLEROSIS. (From Smith and Reynard, Textbook of Pharmacology, 1991, p358) (See all compounds classified as Muscle Relaxants, Central.)


4.2 ATC Code

M - Musculo-skeletal system

M03 - Muscle relaxants

M03B - Muscle relaxants, centrally acting agents

M03BX - Other centrally acting agents

M03BX07 - Tetrazepam


REF. STANDARDS & IMPURITIES

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ABOUT THIS PAGE

Tetrazepam Manufacturers

A Tetrazepam manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Tetrazepam, including repackagers and relabelers. The FDA regulates Tetrazepam manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Tetrazepam API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Tetrazepam Suppliers

A Tetrazepam supplier is an individual or a company that provides Tetrazepam active pharmaceutical ingredient (API) or Tetrazepam finished formulations upon request. The Tetrazepam suppliers may include Tetrazepam API manufacturers, exporters, distributors and traders.

click here to find a list of Tetrazepam suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Tetrazepam CEP

A Tetrazepam CEP of the European Pharmacopoeia monograph is often referred to as a Tetrazepam Certificate of Suitability (COS). The purpose of a Tetrazepam CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Tetrazepam EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Tetrazepam to their clients by showing that a Tetrazepam CEP has been issued for it. The manufacturer submits a Tetrazepam CEP (COS) as part of the market authorization procedure, and it takes on the role of a Tetrazepam CEP holder for the record. Additionally, the data presented in the Tetrazepam CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Tetrazepam DMF.

A Tetrazepam CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Tetrazepam CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Tetrazepam suppliers with CEP (COS) on PharmaCompass.

Tetrazepam GMP

Tetrazepam Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Tetrazepam GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Tetrazepam GMP manufacturer or Tetrazepam GMP API supplier for your needs.

Tetrazepam CoA

A Tetrazepam CoA (Certificate of Analysis) is a formal document that attests to Tetrazepam's compliance with Tetrazepam specifications and serves as a tool for batch-level quality control.

Tetrazepam CoA mostly includes findings from lab analyses of a specific batch. For each Tetrazepam CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Tetrazepam may be tested according to a variety of international standards, such as European Pharmacopoeia (Tetrazepam EP), Tetrazepam JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Tetrazepam USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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