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1. 127502-06-1
2. 3j0kpb596q
3. 3,12-dioxa-6,9-diphosphatetradecane, 6,9-bis(2-ethoxyethyl)-
4. Ethylenebis(bis(2-ethoxyethyl)phosphine)
5. P-53
6. 2-[bis(2-ethoxyethyl)phosphanyl]ethyl-bis(2-ethoxyethyl)phosphane
7. P53
8. Unii-3j0kpb596q
9. Tetrofosmin [usan:inn:ban:jan]
10. P 53
11. Tetrofosmin [ii]
12. Tetrofosmin [mi]
13. Tetrofosmin [inn]
14. Tetrofosmin [jan]
15. Tetrofosmin [usan]
16. Tetrofosmin [who-dd]
17. Schembl136150
18. Tetrofosmin (jan/usan/inn)
19. Chembl1615784
20. Dtxsid70155591
21. Chebi:135598
22. Zinc3780929
23. Db11180
24. D06094
25. Q27257279
Molecular Weight | 382.5 g/mol |
---|---|
Molecular Formula | C18H40O4P2 |
XLogP3 | 0.5 |
Hydrogen Bond Donor Count | 0 |
Hydrogen Bond Acceptor Count | 4 |
Rotatable Bond Count | 19 |
Exact Mass | 382.24018375 g/mol |
Monoisotopic Mass | 382.24018375 g/mol |
Topological Polar Surface Area | 36.9 Ų |
Heavy Atom Count | 24 |
Formal Charge | 0 |
Complexity | 201 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 1 |
1 of 1 | |
---|---|
Drug Name | Myoview |
Drug Label | The MYOVIEW kit is supplied as a pack of five vials for use in the preparation of a technetium Tc99m tetrofosmin intravenous injection to be used for the scintigraphic delineation of regions of reversible myocardial ischemia in the presence |
Active Ingredient | Technetium tc-99m tetrofosmin |
Dosage Form | Injectable |
Route | Injection |
Strength | n/a |
Market Status | Prescription |
Company | Ge Healthcare |
Tetrofosmin is indicated to be used as a complex with technetium Tc-99m for scintigraphic imaging of the myocardium following separate administrations under exercise and/or resting conditions. It helps in the delineation of regions of reversible myocardial ischemia in absence of infarcted myocardium. This complex is also used for scintigraphic imaging of the myocardium to identify changes in perfusion induced by pharmacologic stress in patients with known or suspected coronary artery disease. This complex is indicated for the assessment of left ventricular function in patients evaluated for heart disease.
FDA Label
Refer to [DB09160]
Absorption
After intravenous administration, tetrofosmin is rapidly cleared from the blood and taken up by the heart, skeletal muscle, liver, spleen and kidneys.
Route of Elimination
Refer to [DB09160]
Volume of Distribution
This pharmacokinetic property has not been fully studied.
Clearance
Refer to [DB09160]
This pharmacokinetic property has not been fully studied.
Refer to [DB09160]
Tetrofosmin normal biodistribution makes it suitable to be used as a myocardial agent as it is uptaken by the myocardial tissue and it presents a very low redistribution after 3-4 hours of administration. After distribution, tetrofosmin is a lipophilic cationic agent which is passively diffused and accumulated in viable myocardial tissue.
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PharmaCompass offers a list of Tetrofosmin API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Tetrofosmin manufacturer or Tetrofosmin supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Tetrofosmin manufacturer or Tetrofosmin supplier.
PharmaCompass also assists you with knowing the Tetrofosmin API Price utilized in the formulation of products. Tetrofosmin API Price is not always fixed or binding as the Tetrofosmin Price is obtained through a variety of data sources. The Tetrofosmin Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.
A Tetrofosmin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Tetrofosmin, including repackagers and relabelers. The FDA regulates Tetrofosmin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Tetrofosmin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Tetrofosmin supplier is an individual or a company that provides Tetrofosmin active pharmaceutical ingredient (API) or Tetrofosmin finished formulations upon request. The Tetrofosmin suppliers may include Tetrofosmin API manufacturers, exporters, distributors and traders.
National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Tetrofosmin as an active pharmaceutical ingredient (API).
The FDA updates the NDC directory daily. The NDC numbers for Tetrofosmin API and other APIs are published in this directory by the FDA.
The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.
Pharmaceutical companies that manufacture Tetrofosmin as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.
The NDC directory also contains data on finished compounded human drug products that contain Tetrofosmin and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Tetrofosmin NDC to their finished compounded human drug products, they may choose to do so.
click here to find a list of Tetrofosmin suppliers with NDC on PharmaCompass.
Tetrofosmin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Tetrofosmin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Tetrofosmin GMP manufacturer or Tetrofosmin GMP API supplier for your needs.
A Tetrofosmin CoA (Certificate of Analysis) is a formal document that attests to Tetrofosmin's compliance with Tetrofosmin specifications and serves as a tool for batch-level quality control.
Tetrofosmin CoA mostly includes findings from lab analyses of a specific batch. For each Tetrofosmin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Tetrofosmin may be tested according to a variety of international standards, such as European Pharmacopoeia (Tetrofosmin EP), Tetrofosmin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Tetrofosmin USP).