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Chemistry

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Also known as: Thallium-201 chloride, Allous chloride tl-201, Thallous chloride t1-201, (201)tlcl, (201-tl)thallous chloride, Thallium-201(1+) chloride
Molecular Formula
ClTl
Molecular Weight
236.42  g/mol
InChI Key
GBECUEIQVRDUKB-RYDPDVNUSA-M

Thallium-201 Chloride
Thallous Chloride Tl-201 is the chloride salt form of thallium-201, a cyclotron produced isotope use in diagnostic imaging. Thallous chloride TI-201 accumulates in myocardial cells and other tissues in an analogous way as potassium, and can be evaluated as a function of blood flow. By scintigraphic means, areas with decreased blood flow, consisting of ischemic cells, can be visualized due to decreased uptake of TI-201 in contrast to areas with normal blood flow.
1 2D Structure

Thallium-201 Chloride

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
chloro(201Tl)thallium-201
2.1.2 InChI
InChI=1S/ClH.Tl/h1H;/q;+1/p-1/i;1-3
2.1.3 InChI Key
GBECUEIQVRDUKB-RYDPDVNUSA-M
2.1.4 Canonical SMILES
Cl[Tl]
2.1.5 Isomeric SMILES
Cl[201Tl]
2.2 Synonyms
2.2.1 Depositor-Supplied Synonyms

1. Thallium-201 Chloride

2. Allous Chloride Tl-201

3. Thallous Chloride T1-201

4. (201)tlcl

5. (201-tl)thallous Chloride

6. Thallium-201(1+) Chloride

7. Unii-3i8y076a0e

8. Thallous Chloride (201tlcl)

9. ((201)tl)thallium Monochloride

10. Chebi:32213

11. ((201)tl)thallium(i) Chloride

12. ((201)tl)thallium(1+) Chloride

13. Thallium Chloride ((sup 201)tlcl)

14. Thallous Chloride Tl 201 [usan:usp]

15. Thallium Chloride ((sup 201)tl) Injection

16. Q27114831

2.3 Create Date
2007-04-03
3 Chemical and Physical Properties
Molecular Weight 236.42 g/mol
Molecular Formula ClTl
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count0
Rotatable Bond Count0
Exact Mass235.9397 g/mol
Monoisotopic Mass235.9397 g/mol
Topological Polar Surface Area0 Ų
Heavy Atom Count2
Formal Charge0
Complexity2
Isotope Atom Count1
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Information
1 of 2  
Drug NameThallous chloride tl 201
PubMed HealthThallous Chloride Tl 201 (Injection)
Drug ClassesDiagnostic Agent, Radiopharmaceutical Imaging
Active IngredientThallous chloride tl-201
Dosage FormInjectable
RouteInjection; Intravenous
Strength1mci/ml; 2mci/ml
Market StatusPrescription
CompanyMallinckrodt; Lantheus Medcl; Ge Healthcare

2 of 2  
Drug NameThallous chloride tl 201
PubMed HealthThallous Chloride Tl 201 (Injection)
Drug ClassesDiagnostic Agent, Radiopharmaceutical Imaging
Active IngredientThallous chloride tl-201
Dosage FormInjectable
RouteInjection; Intravenous
Strength1mci/ml; 2mci/ml
Market StatusPrescription
CompanyMallinckrodt; Lantheus Medcl; Ge Healthcare

5 Pharmacology and Biochemistry
5.1 FDA Pharmacological Classification
5.1.1 Pharmacological Classes
Radiopharmaceutical Activity [MoA]; Radioactive Diagnostic Agent [EPC]

ABOUT THIS PAGE

Thallous chloride tl 201 Manufacturers

A Thallous chloride tl 201 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Thallous chloride tl 201, including repackagers and relabelers. The FDA regulates Thallous chloride tl 201 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Thallous chloride tl 201 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Thallous chloride tl 201 Suppliers

A Thallous chloride tl 201 supplier is an individual or a company that provides Thallous chloride tl 201 active pharmaceutical ingredient (API) or Thallous chloride tl 201 finished formulations upon request. The Thallous chloride tl 201 suppliers may include Thallous chloride tl 201 API manufacturers, exporters, distributors and traders.

click here to find a list of Thallous chloride tl 201 suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Thallous chloride tl 201 USDMF

A Thallous chloride tl 201 DMF (Drug Master File) is a document detailing the whole manufacturing process of Thallous chloride tl 201 active pharmaceutical ingredient (API) in detail. Different forms of Thallous chloride tl 201 DMFs exist exist since differing nations have different regulations, such as Thallous chloride tl 201 USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Thallous chloride tl 201 DMF submitted to regulatory agencies in the US is known as a USDMF. Thallous chloride tl 201 USDMF includes data on Thallous chloride tl 201's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Thallous chloride tl 201 USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Thallous chloride tl 201 suppliers with USDMF on PharmaCompass.

Thallous chloride tl 201 GMP

Thallous chloride tl 201 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Thallous chloride tl 201 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Thallous chloride tl 201 GMP manufacturer or Thallous chloride tl 201 GMP API supplier for your needs.

Thallous chloride tl 201 CoA

A Thallous chloride tl 201 CoA (Certificate of Analysis) is a formal document that attests to Thallous chloride tl 201's compliance with Thallous chloride tl 201 specifications and serves as a tool for batch-level quality control.

Thallous chloride tl 201 CoA mostly includes findings from lab analyses of a specific batch. For each Thallous chloride tl 201 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Thallous chloride tl 201 may be tested according to a variety of international standards, such as European Pharmacopoeia (Thallous chloride tl 201 EP), Thallous chloride tl 201 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Thallous chloride tl 201 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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