Granules India Limited has high volume world-class facilities for APIs, PFIs, & FDFs, serving customers in over 80 countries.

Contact Supplier

Jai Radhe Sales is your partner for all your sourcing needs.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

1 API Suppliers, 1 USDMF, 2 NDC API, 5 VMF

1 API Suppliers
1 USDMF
2 NDC API
5 VMF

DEVELOPMENTS

2 Drugs in Development

2 Drugs in Development

RELATED EXCIPIENT COMPANIES

1 Rochem International Inc, 2 SPI Pharma, 3 DKSH, 1 Gangwal Healthcare, 2 Nanjing Well Pharmaceutical, 1 Actylis, 2 BASF, 1 Finar, 1 Gangwal Chemicals, 5 Kerry, 11 Roquette, 1 Shijiazhuang Huaxu Pharmaceutical, 1 Valens Pharmachem, 1 Zhejiang Huakang Pharmaceutical

relatedExcipients
1 Rochem International Inc
2 SPI Pharma
3 DKSH
1 Gangwal Healthcare
2 Nanjing Well Pharmaceutical
1 Actylis
2 BASF
1 Finar
1 Gangwal Chemicals
5 Kerry
11 Roquette
1 Shijiazhuang Huaxu Pharmaceutical
1 Valens Pharmachem
1 Zhejiang Huakang Pharmaceutical

EXCIPIENTS BY APPLICATIONS

11 Film Formers & Plasticizers, 8 Coating Systems & Additives, 6 Topical, 6 Co-Processed Excipients, 5 Taste Masking, 4 Solubilizers, 4 Fillers, Diluents & Binders, 3 Parenteral, 2 Chewable & Orodispersible Aids, 2 Coloring Agents, 1 Soft Gelatin, 1 Emulsifying Agents, 1 Thickeners and Stabilizers, 1 Direct Compression

excipientsByApplications
11 Film Formers & Plasticizers
8 Coating Systems & Additives
6 Topical
6 Co-Processed Excipients
5 Taste Masking
4 Solubilizers
4 Fillers, Diluents & Binders
3 Parenteral
2 Chewable & Orodispersible Aids
2 Coloring Agents
1 Soft Gelatin
1 Emulsifying Agents
1 Thickeners and Stabilizers
1 Direct Compression

MARKET PLACE

1 APIs

marketPlace
1 APIs

REF. STANDARDS & IMPURITIES

1 USP , 1 Others

otherSolutions
1 USP
1 Others

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

2DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

33 RELATED EXCIPIENT COMPANIES

55EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: Thiostrepton, Thiactin, 1393-48-2, Sr-05000001899, Ncgc00016576-01, Cas-1393-48-2

Molecular Formula

C₇₂H₈₅N₁₉O₁₈S₅

Molecular Weight

1664.9 g/mol

InChI Key

NSFFHOGKXHRQEW-DVRIZHICSA-N

One of the CYCLIC PEPTIDES from Streptomyces that is active against gram-positive bacteria. In veterinary medicine, it has been used in mastitis caused by gram-negative organisms and in dermatologic disorders.

1 2D Structure

Thiostrepton

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

N-[3-[(3-amino-3-oxoprop-1-en-2-yl)amino]-3-oxoprop-1-en-2-yl]-2-[(11E)-37-butan-2-yl-18-(2,3-dihydroxybutan-2-yl)-11-ethylidene-59-hydroxy-8,31-bis(1-hydroxyethyl)-26,40,46-trimethyl-43-methylidene-6,9,16,23,28,38,41,44,47-nonaoxo-27-oxa-3,13,20,56-tetrathia-7,10,17,24,36,39,42,45,48,52,58,61,62,63,64-pentadecazanonacyclo[23.23.9.329,35.12,5.112,15.119,22.154,57.01,53.032,60]tetrahexaconta-2(64),4,12(63),19(62),21,29(61),30,32(60),33,51,54,57-dodecaen-51-yl]-1,3-thiazole-4-carboxamide

2.1.2 InChI

InChI=1S/C72H85N19O18S5/c1-14-26(3)47-63(105)78-30(7)57(99)75-28(5)56(98)76-31(8)58(100)91-72-19-18-40(66-85-43(22-111-66)59(101)77-29(6)55(97)74-27(4)54(73)96)81-52(72)42-21-112-67(83-42)49(34(11)109-69(107)41-20-37(32(9)92)36-16-17-39(79-47)51(95)50(36)80-41)89-60(102)44-24-113-68(86-44)53(71(13,108)35(12)94)90-62(104)45-23-110-65(84-45)38(15-2)82-64(106)48(33(10)93)88-61(103)46-25-114-70(72)87-46/h15-17,20-22,24-26,30-35,39,45,47-49,51-53,79,92-95,108H,4-6,14,18-19,23H2,1-3,7-13H3,(H2,73,96)(H,74,97)(H,75,99)(H,76,98)(H,77,101)(H,78,105)(H,82,106)(H,88,103)(H,89,102)(H,90,104)(H,91,100)/b38-15+

2.1.3 InChI Key

NSFFHOGKXHRQEW-DVRIZHICSA-N

2.1.4 Canonical SMILES

CCC(C)C1C(=O)NC(C(=O)NC(=C)C(=O)NC(C(=O)NC23CCC(=NC2C4=CSC(=N4)C(C(OC(=O)C5=NC6=C(C=CC(C6O)N1)C(=C5)C(C)O)C)NC(=O)C7=CSC(=N7)C(NC(=O)C8CSC(=N8)C(=CC)NC(=O)C(NC(=O)C9=CSC3=N9)C(C)O)C(C)(C(C)O)O)C1=NC(=CS1)C(=O)NC(=C)C(=O)NC(=C)C(=O)N)C)C

2.1.5 Isomeric SMILES

CCC(C)C1C(=O)NC(C(=O)NC(=C)C(=O)NC(C(=O)NC23CCC(=NC2C4=CSC(=N4)C(C(OC(=O)C5=NC6=C(C=CC(C6O)N1)C(=C5)C(C)O)C)NC(=O)C7=CSC(=N7)C(NC(=O)C8CSC(=N8)/C(=C\C)/NC(=O)C(NC(=O)C9=CSC3=N9)C(C)O)C(C)(C(C)O)O)C1=NC(=CS1)C(=O)NC(=C)C(=O)NC(=C)C(=O)N)C)C

2.2 Synonyms

2.2.1 MeSH Synonyms

1. Gargon

2. Thiactin

3. Thiostrepton

2.2.2 Depositor-Supplied Synonyms

1. Thiostrepton

2. Thiactin

3. 1393-48-2

4. Sr-05000001899

5. Ncgc00016576-01

6. Cas-1393-48-2

7. Prestwick2_000522

8. Dsstox_cid_20625

9. Dsstox_rid_79517

10. Dsstox_gsid_40625

11. Schembl25847

12. Bspbio_002468

13. Spectrum1505111

14. Chembl410968

15. Hms1569j05

16. Hms2093i06

17. Pharmakon1600-01505111

18. Tox21_110504

19. Nsc759821

20. Akos026750174

21. Ccg-213336

22. Nsc-759821

23. Ncgc00096010-01

24. Ncgc00096010-02

25. Sbi-0206784.p001

26. Ab01563039_01

27. Sr-05000001899-1

28. Sr-05000001899-3

29. Sr-05000001899-4

2.3 Create Date

2007-07-03

3 Chemical and Physical Properties

Molecular Formula	C₇₂H₈₅N₁₉O₁₈S₅
Molecular Weight	1664.9 g/mol
XLogP3	0.6
Hydrogen Bond Donor Count	17
Hydrogen Bond Acceptor Count	31
Rotatable Bond Count	12
Exact Mass	1663.4923528 g/mol
Monoisotopic Mass	1663.4923528 g/mol
Topological Polar Surface Area	701 Å²
Heavy Atom Count	114
Formal Charge	0
Complexity	3940
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	17
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)

API SUPPLIERS

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

USDMF

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

NDC API

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

VMF

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Drugs in Development

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Related Excipient Companies

Upload your portfolio for free, ask us

Excipients by Applications

Click here to find the perfect excipient manufacturers by their capabilities

Film Formers & Plasticizers

Coating Systems & Additives

Topical

Co-Processed Excipients

Taste Masking

Solubilizers

Fillers, Diluents & Binders

Parenteral

Chewable & Orodispersible Aids

Coloring Agents

Soft Gelatin

Emulsifying Agents

Thickeners and Stabilizers

Direct Compression

Market Place

Do you need sourcing support? Ask us

APIs

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

REF. STANDARDS & IMPURITIES

Upload your portfolio for free, ask us

USP

Others

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

ABOUT THIS PAGE

Find Thiostrepton manufacturers, exporters & distributors on PharmaCompass

Thiostrepton

ACCESS ALL DATA

Browse all information

CHEMISTRY

Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

1 API Suppliers

1 USDMF

2 NDC API

5 VMF

DEVELOPMENTS

2 Drugs in Development

RELATED EXCIPIENT COMPANIES

1 Rochem International Inc

2 SPI Pharma

3 DKSH

1 Gangwal Healthcare

2 Nanjing Well Pharmaceutical

1 Actylis

2 BASF

1 Finar

1 Gangwal Chemicals

5 Kerry

11 Roquette

1 Shijiazhuang Huaxu Pharmaceutical

1 Valens Pharmachem

1 Zhejiang Huakang Pharmaceutical

EXCIPIENTS BY APPLICATIONS

11 Film Formers & Plasticizers

8 Coating Systems & Additives

6 Topical

6 Co-Processed Excipients

5 Taste Masking

4 Solubilizers

4 Fillers, Diluents & Binders

3 Parenteral

2 Chewable & Orodispersible Aids

2 Coloring Agents

1 Soft Gelatin

1 Emulsifying Agents

1 Thickeners and Stabilizers

1 Direct Compression

MARKET PLACE

1 APIs

REF. STANDARDS & IMPURITIES

1 USP

1 Others

ACTIVE PHARMA INGREDIENTS

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

2DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

PATENTS & EXCLUSIVITIES

DIGITAL CONTENT

GLOBAL SALES INFORMATION

33 RELATED EXCIPIENT COMPANIES

55EXCIPIENTS BY APPLICATIONS

What are you looking for?