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1. Acid, Thienylic
2. Acid, Tienilic
3. Anp 3624
4. Anp-3624
5. Anp3624
6. Selacryn
7. Skf 62698
8. Skf-62698
9. Skf62698
10. Thienylic Acid
11. Ticrynafen
1. Ticrynafen
2. 40180-04-9
3. Thienylic Acid
4. Selacryn
5. Diflurex
6. Ticrex
7. Ticrynafen [usan]
8. Acido Tienilico
9. Acide Tienilique
10. Acidum Tienilicum
11. 2-(2,3-dichloro-4-(thiophene-2-carbonyl)phenoxy)acetic Acid
12. (2,3-dichloro-4-(2-thenoyl)phenoxy)acetic Acid
13. 4-(2-thienylketo)-2,3-dichlorophenoxyacetic Acid
14. 2-[2,3-dichloro-4-(thiophene-2-carbonyl)phenoxy]acetic Acid
15. (2,3-dichloro-4-(2-thiophenecarbonyl)phenoxy)acetic Acid
16. Tienilic Acid [inn]
17. [2,3-dichloro-4-(2-thienylcarbonyl)phenoxy]acetic Acid
18. Sk&f 62698
19. (2,3-dichloro-4-(2-thienylcarbonyl)phenoxy)acetic Acid
20. Chebi:9590
21. Chembl267744
22. 4-(2-theonyl)-2,3-dichlorphenoxyessigsaeure
23. Anp 362
24. Acetic Acid, (2,3-dichloro-4-(2-thienylcarbonyl)phenoxy)-
25. Hc95205sy4
26. Ticrynafen (usan)
27. Tienilic Acid (inn)
28. Ncgc00159454-02
29. Ncgc00159454-03
30. Acetic Acid, [2,3-dichloro-4-(2-thienylcarbonyl)phenoxy]-
31. Dsstox_cid_3670
32. Dsstox_rid_77137
33. Dsstox_gsid_23670
34. Tienilico Acido [spanish]
35. Acide Tienilique [inn-french]
36. Acido Tienilico [inn-spanish]
37. Acidum Tienilicum [inn-latin]
38. Tienilico Acido
39. 2-{2,3-dichloro-4-[(thiophen-2-yl)carbonyl]phenoxy}acetic Acid
40. Anp 3624
41. Skf 62698
42. Cas-40180-04-9
43. Ccris 5489
44. Einecs 254-826-3
45. Ce 3624
46. Fr 3068
47. Brn 1260086
48. Ticrynafan
49. {[2,3-dichloro-4-(2-thienylcarbonyl)phenyl]oxy}acetic Acid
50. 4-(2-theonyl)-2,3-dichlorphenoxyessigsaeure [german]
51. Tienilic-acid
52. Unii-hc95205sy4
53. Selacryn (tn)
54. Ticrynafen [mi]
55. Ticrynafen, Tienilic Acid
56. 5-18-02-00008 (beilstein Handbook Reference)
57. Schembl123608
58. Tienilic Acid [mart.]
59. Zinc2166
60. Tienilic Acid [who-dd]
61. Dtxsid4023670
62. Hms3650c20
63. Tienilic Acid, >=98% (hplc)
64. Tox21_111681
65. Tox21_111682
66. Bdbm50090674
67. Mfcd00867339
68. Akos000280732
69. Db04831
70. Sk&f-62698
71. Ncgc00159454-04
72. Ncgc00159454-09
73. Da-20731
74. Hy-21065
75. Cs-0012688
76. Ft-0675229
77. D02386
78. 7z-0042
79. Sr-00000000556
80. Q7801054
81. Sr-00000000556-2
82. Brd-k34098590-001-01-3
83. 2,3-dichloro-4-(2-thienylcarbonyl)-phenoxyacetic Acid
84. [2,3-dichloro-4-(thiophene-2-carbonyl)-phenoxy]-acetic Acid
85. [2,3-dichloro-4-(thiophene-2-carbonyl)-phenoxyl]-acetic Acid
86. 2-(2,3-dichloro-4-(thiophene-2-carbonyl)phenoxy)aceticacid
87. [2,3-dichloro-4-(thiophene-2-carbonyl)-phenoxy]-acetic Acid(ticrynafen)
88. [2,3-dichloro-4-(thiophene-2-carbonyl)-phenoxy]-acetic Acid(tienilic Acid)
89. [2,3-dichloro-4-(thiophene-2-carbonyl)-phenoxy]-acetic Acid (tienilic Acid)
Molecular Weight | 331.2 g/mol |
---|---|
Molecular Formula | C13H8Cl2O4S |
XLogP3 | 4.1 |
Hydrogen Bond Donor Count | 1 |
Hydrogen Bond Acceptor Count | 5 |
Rotatable Bond Count | 5 |
Exact Mass | 329.9520353 g/mol |
Monoisotopic Mass | 329.9520353 g/mol |
Topological Polar Surface Area | 91.8 Ų |
Heavy Atom Count | 20 |
Formal Charge | 0 |
Complexity | 379 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 1 |
For the treatment of hypertension.
Antihypertensive Agents
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. (See all compounds classified as Antihypertensive Agents.)
Uricosuric Agents
Gout suppressants that act directly on the renal tubule to increase the excretion of uric acid, thus reducing its concentrations in plasma. (See all compounds classified as Uricosuric Agents.)
Diuretics
Agents that promote the excretion of urine through their effects on kidney function. (See all compounds classified as Diuretics.)
C - Cardiovascular system
C03 - Diuretics
C03C - High-ceiling diuretics
C03CC - Aryloxyacetic acid derivatives
C03CC02 - Tienilic acid
Ticrynafen has known human metabolites that include Thiophene-4,5-epoxide and Tienilic acid-s-oxide.
S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560
ABOUT THIS PAGE
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PharmaCompass offers a list of Ticrynafen API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Ticrynafen manufacturer or Ticrynafen supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Ticrynafen manufacturer or Ticrynafen supplier.
PharmaCompass also assists you with knowing the Ticrynafen API Price utilized in the formulation of products. Ticrynafen API Price is not always fixed or binding as the Ticrynafen Price is obtained through a variety of data sources. The Ticrynafen Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.
A Ticrynafen manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ticrynafen, including repackagers and relabelers. The FDA regulates Ticrynafen manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ticrynafen API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Ticrynafen supplier is an individual or a company that provides Ticrynafen active pharmaceutical ingredient (API) or Ticrynafen finished formulations upon request. The Ticrynafen suppliers may include Ticrynafen API manufacturers, exporters, distributors and traders.
click here to find a list of Ticrynafen suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
A Ticrynafen DMF (Drug Master File) is a document detailing the whole manufacturing process of Ticrynafen active pharmaceutical ingredient (API) in detail. Different forms of Ticrynafen DMFs exist exist since differing nations have different regulations, such as Ticrynafen USDMF, ASMF (EDMF), JDMF, CDMF, etc.
A Ticrynafen DMF submitted to regulatory agencies in the US is known as a USDMF. Ticrynafen USDMF includes data on Ticrynafen's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Ticrynafen USDMF is kept confidential to protect the manufacturer’s intellectual property.
click here to find a list of Ticrynafen suppliers with USDMF on PharmaCompass.
Ticrynafen Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Ticrynafen GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ticrynafen GMP manufacturer or Ticrynafen GMP API supplier for your needs.
A Ticrynafen CoA (Certificate of Analysis) is a formal document that attests to Ticrynafen's compliance with Ticrynafen specifications and serves as a tool for batch-level quality control.
Ticrynafen CoA mostly includes findings from lab analyses of a specific batch. For each Ticrynafen CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Ticrynafen may be tested according to a variety of international standards, such as European Pharmacopoeia (Ticrynafen EP), Ticrynafen JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ticrynafen USP).