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1. Acid, Thienylic
2. Acid, Tienilic
3. Anp 3624
4. Anp-3624
5. Anp3624
6. Selacryn
7. Skf 62698
8. Skf-62698
9. Skf62698
10. Thienylic Acid
11. Ticrynafen
1. Ticrynafen
2. 40180-04-9
3. Thienylic Acid
4. Selacryn
5. Diflurex
6. Ticrex
7. Ticrynafen [usan]
8. Acido Tienilico
9. Acide Tienilique
10. Acidum Tienilicum
11. 2-(2,3-dichloro-4-(thiophene-2-carbonyl)phenoxy)acetic Acid
12. (2,3-dichloro-4-(2-thenoyl)phenoxy)acetic Acid
13. 4-(2-thienylketo)-2,3-dichlorophenoxyacetic Acid
14. 2-[2,3-dichloro-4-(thiophene-2-carbonyl)phenoxy]acetic Acid
15. (2,3-dichloro-4-(2-thiophenecarbonyl)phenoxy)acetic Acid
16. Tienilic Acid [inn]
17. [2,3-dichloro-4-(2-thienylcarbonyl)phenoxy]acetic Acid
18. Sk&f 62698
19. (2,3-dichloro-4-(2-thienylcarbonyl)phenoxy)acetic Acid
20. Chebi:9590
21. Chembl267744
22. 4-(2-theonyl)-2,3-dichlorphenoxyessigsaeure
23. Anp 362
24. Acetic Acid, (2,3-dichloro-4-(2-thienylcarbonyl)phenoxy)-
25. Hc95205sy4
26. Ticrynafen (usan)
27. Tienilic Acid (inn)
28. Ncgc00159454-02
29. Ncgc00159454-03
30. Acetic Acid, [2,3-dichloro-4-(2-thienylcarbonyl)phenoxy]-
31. Dsstox_cid_3670
32. Dsstox_rid_77137
33. Dsstox_gsid_23670
34. Tienilico Acido [spanish]
35. Acide Tienilique [inn-french]
36. Acido Tienilico [inn-spanish]
37. Acidum Tienilicum [inn-latin]
38. Tienilico Acido
39. 2-{2,3-dichloro-4-[(thiophen-2-yl)carbonyl]phenoxy}acetic Acid
40. Anp 3624
41. Skf 62698
42. Cas-40180-04-9
43. Ccris 5489
44. Einecs 254-826-3
45. Ce 3624
46. Fr 3068
47. Brn 1260086
48. Ticrynafan
49. {[2,3-dichloro-4-(2-thienylcarbonyl)phenyl]oxy}acetic Acid
50. 4-(2-theonyl)-2,3-dichlorphenoxyessigsaeure [german]
51. Tienilic-acid
52. Unii-hc95205sy4
53. Selacryn (tn)
54. Ticrynafen [mi]
55. Ticrynafen, Tienilic Acid
56. 5-18-02-00008 (beilstein Handbook Reference)
57. Schembl123608
58. Tienilic Acid [mart.]
59. Zinc2166
60. Tienilic Acid [who-dd]
61. Dtxsid4023670
62. Hms3650c20
63. Tienilic Acid, >=98% (hplc)
64. Tox21_111681
65. Tox21_111682
66. Bdbm50090674
67. Mfcd00867339
68. Akos000280732
69. Db04831
70. Sk&f-62698
71. Ncgc00159454-04
72. Ncgc00159454-09
73. Da-20731
74. Hy-21065
75. Cs-0012688
76. Ft-0675229
77. D02386
78. 7z-0042
79. Sr-00000000556
80. Q7801054
81. Sr-00000000556-2
82. Brd-k34098590-001-01-3
83. 2,3-dichloro-4-(2-thienylcarbonyl)-phenoxyacetic Acid
84. [2,3-dichloro-4-(thiophene-2-carbonyl)-phenoxy]-acetic Acid
85. [2,3-dichloro-4-(thiophene-2-carbonyl)-phenoxyl]-acetic Acid
86. 2-(2,3-dichloro-4-(thiophene-2-carbonyl)phenoxy)aceticacid
87. [2,3-dichloro-4-(thiophene-2-carbonyl)-phenoxy]-acetic Acid(ticrynafen)
88. [2,3-dichloro-4-(thiophene-2-carbonyl)-phenoxy]-acetic Acid(tienilic Acid)
89. [2,3-dichloro-4-(thiophene-2-carbonyl)-phenoxy]-acetic Acid (tienilic Acid)
Molecular Weight | 331.2 g/mol |
---|---|
Molecular Formula | C13H8Cl2O4S |
XLogP3 | 4.1 |
Hydrogen Bond Donor Count | 1 |
Hydrogen Bond Acceptor Count | 5 |
Rotatable Bond Count | 5 |
Exact Mass | 329.9520353 g/mol |
Monoisotopic Mass | 329.9520353 g/mol |
Topological Polar Surface Area | 91.8 Ų |
Heavy Atom Count | 20 |
Formal Charge | 0 |
Complexity | 379 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 1 |
For the treatment of hypertension.
Antihypertensive Agents
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. (See all compounds classified as Antihypertensive Agents.)
Uricosuric Agents
Gout suppressants that act directly on the renal tubule to increase the excretion of uric acid, thus reducing its concentrations in plasma. (See all compounds classified as Uricosuric Agents.)
Diuretics
Agents that promote the excretion of urine through their effects on kidney function. (See all compounds classified as Diuretics.)
C - Cardiovascular system
C03 - Diuretics
C03C - High-ceiling diuretics
C03CC - Aryloxyacetic acid derivatives
C03CC02 - Tienilic acid
Ticrynafen has known human metabolites that include Thiophene-4,5-epoxide and Tienilic acid-s-oxide.
S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560