Find Timiperone manufacturers, exporters & distributors on PharmaCompass

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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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USDMF

US DMFs Filed

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CEP/COS

CEP/COS Certifications

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EU WC

EU WC

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KDMF

KDMF

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NDC API

NDC API

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VMF

NDC API

API REF. PRICE (USD/KG)

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MARKET PLACE

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API

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FDF

FINISHED DOSAGE FORMULATIONS

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FDF Dossiers

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FDA Orange Book

FDA (Orange Book)

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Europe

Europe

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Canada

Canada

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Australia

Australia

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South Africa

South Africa

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Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

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EDQM

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USP

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JP

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Others

PATENTS & EXCLUSIVITIES

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US Patents

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Health Canada Patents

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GLOBAL SALES INFORMATION

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Chemistry

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Also known as: 57648-21-2, Tolopelon, Dd-3480, 1-(1-(3-(p-fluorobenzoyl)propyl)-4-piperidyl)-2-benzimidazolinethione, 626dq7n19l, Timiperone (jan)
Molecular Formula
C22H24FN3OS
Molecular Weight
397.5  g/mol
InChI Key
YDLQKLWVKKFPII-UHFFFAOYSA-N
FDA UNII
626DQ7N19L

Timiperone
1 2D Structure

Timiperone

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-(4-fluorophenyl)-4-[4-(2-sulfanylidene-3H-benzimidazol-1-yl)piperidin-1-yl]butan-1-one
2.1.2 InChI
InChI=1S/C22H24FN3OS/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-10,18H,3,6,11-15H2,(H,24,28)
2.1.3 InChI Key
YDLQKLWVKKFPII-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1CN(CCC1N2C3=CC=CC=C3NC2=S)CCCC(=O)C4=CC=C(C=C4)F
2.2 Other Identifiers
2.2.1 UNII
626DQ7N19L
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 4'-fluoro-4-(4-(2-thioxo-1-benzimidazolinyl)piperidino)butyrophenone

2. Dd 3480

2.3.2 Depositor-Supplied Synonyms

1. 57648-21-2

2. Tolopelon

3. Dd-3480

4. 1-(1-(3-(p-fluorobenzoyl)propyl)-4-piperidyl)-2-benzimidazolinethione

5. 626dq7n19l

6. Timiperone (jan)

7. Timiperone [jan]

8. 4-fluoro-4-(4-(2-thioxo-1-benzimidazolinyl)piperidino)butyrophenone

9. 1-butanone, 4-(4-(2,3-dihydro-2-thioxo-1h-benzimidazol-1-yl)-1-piperidinyl)-1-(4-fluorophenyl)-

10. Timiperona

11. Timiperonum

12. Timiperone [inn:jan]

13. Timiperonum [inn-latin]

14. Timiperona [inn-spanish]

15. 1-butanone, 4-[4-(2,3-dihydro-2-thioxo-1h-benzimidazol-1-yl)-1-piperidinyl]-1-(4-fluorophenyl)-

16. Ncgc00182555-01

17. Einecs 260-880-9

18. Dd 3480

19. Unii-626dq7n19l

20. Tolopelon (tn)

21. Timiperone [mi]

22. Timiperone [inn]

23. 4'-fluoro-4-(4-(2-thioxo-1-benzimidazolinyl)piperidino)butyrophenone

24. Butyrophenone, 4'-fluoro-4-(4-(2-thioxobenzimidazol-1-yl)piperidino)-

25. Dsstox_cid_3673

26. 2-benzimidazolinethione, 1-(1-(3-(p-fluorobenzoyl)propyl)-4-piperidyl)-

27. Timiperone [mart.]

28. 1-(4-fluorophenyl)-4-[4-(2-sulfanylidene-3h-benzimidazol-1-yl)piperidin-1-yl]butan-1-one

29. Dsstox_rid_77139

30. Timiperone [who-dd]

31. Dsstox_gsid_23673

32. Schembl145839

33. Chembl2107117

34. Dtxsid9023673

35. Schembl11797177

36. Chebi:135631

37. Zinc3873392

38. Tox21_113628

39. Akos025396887

40. Ncgc00387301-01

41. 4-(4-(2,3-dihydro-2-thioxo-1h-benzimidazol-1-yl)-1-piperidinyl)-1-(4-fluorophenyl)-1-butanone

42. Cas-57648-21-2

43. Ft-0675238

44. D02035

45. 648t212

46. Q7806745

47. 1-[1-(3-(4-fluorobenzoyl)propyl)-4-piperidyl]-2-mercaptobenzimidazole

48. 1-(4-fluorophenyl)-4-[4-(2-thioxo-2,3-dihydro-1h-benzimidazol-1-yl)piperidin-1-yl]butan-1-one

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 397.5 g/mol
Molecular Formula C22H24FN3OS
XLogP34.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count6
Exact Mass397.16241173 g/mol
Monoisotopic Mass397.16241173 g/mol
Topological Polar Surface Area67.7 Ų
Heavy Atom Count28
Formal Charge0
Complexity558
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antiemetics

Drugs used to prevent NAUSEA or VOMITING. (See all compounds classified as Antiemetics.)


Antipsychotic Agents

Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus. (See all compounds classified as Antipsychotic Agents.)


API SUPPLIERS

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ABOUT THIS PAGE

Timiperone Manufacturers

A Timiperone manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Timiperone, including repackagers and relabelers. The FDA regulates Timiperone manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Timiperone API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Timiperone manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Timiperone Suppliers

A Timiperone supplier is an individual or a company that provides Timiperone active pharmaceutical ingredient (API) or Timiperone finished formulations upon request. The Timiperone suppliers may include Timiperone API manufacturers, exporters, distributors and traders.

click here to find a list of Timiperone suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Timiperone JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Timiperone Drug Master File in Japan (Timiperone JDMF) empowers Timiperone API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Timiperone JDMF during the approval evaluation for pharmaceutical products. At the time of Timiperone JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Timiperone suppliers with JDMF on PharmaCompass.

Timiperone GMP

Timiperone Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Timiperone GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Timiperone GMP manufacturer or Timiperone GMP API supplier for your needs.

Timiperone CoA

A Timiperone CoA (Certificate of Analysis) is a formal document that attests to Timiperone's compliance with Timiperone specifications and serves as a tool for batch-level quality control.

Timiperone CoA mostly includes findings from lab analyses of a specific batch. For each Timiperone CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Timiperone may be tested according to a variety of international standards, such as European Pharmacopoeia (Timiperone EP), Timiperone JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Timiperone USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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