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Chemistry

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Also known as: Asverin, 5169-78-8, At 327, 3-(di-2-thienylmethylene)-1-methylpiperidine, Cr/662, Crj662
Molecular Formula
C15H17NS2
Molecular Weight
275.4  g/mol
InChI Key
JWIXXNLOKOAAQT-UHFFFAOYSA-N
FDA UNII
2260ZP67IT

Tipepidine
1 2D Structure

Tipepidine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
3-(dithiophen-2-ylmethylidene)-1-methylpiperidine
2.1.2 InChI
InChI=1S/C15H17NS2/c1-16-8-2-5-12(11-16)15(13-6-3-9-17-13)14-7-4-10-18-14/h3-4,6-7,9-10H,2,5,8,11H2,1H3
2.1.3 InChI Key
JWIXXNLOKOAAQT-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CN1CCCC(=C(C2=CC=CS2)C3=CC=CS3)C1
2.2 Other Identifiers
2.2.1 UNII
2260ZP67IT
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Tipepidine Citrate (1:1)

2. Tipepidine Hibenzate

3. Tipepidine Ibenzato

2.3.2 Depositor-Supplied Synonyms

1. Asverin

2. 5169-78-8

3. At 327

4. 3-(di-2-thienylmethylene)-1-methylpiperidine

5. Cr/662

6. Crj662

7. Bitiodin

8. Tipedine

9. 2260zp67it

10. Tipepidine (inn)

11. At-327

12. Cr-662

13. Ncgc00167424-01

14. Tipepidine [inn]

15. Tipepidina

16. Tipepidinum

17. Tipepidine [inn:dcf]

18. Tipepidinum [inn-latin]

19. Tipepidina [inn-spanish]

20. Brn 0212554

21. Tipepidin

22. Unii-2260zp67it

23. 1-methyl-3-piperidylidenedi(2-thienyl)methane

24. 3-(di-2-thienylmethylene)-1-methyl-piperidine

25. 3-(dithiophen-2-ylmethylidene)-1-methylpiperidine

26. Piperidine, 3-(di-2-thienylmethylene)-1-methyl-

27. Tipepidine [mi]

28. Dsstox_cid_2626

29. Piperidine, 3-(di-2-thienylmethyle)-1-methyl-

30. Dsstox_rid_82577

31. Tipepidine [who-dd]

32. Dsstox_gsid_22626

33. Oprea1_194078

34. Oprea1_494302

35. Cbdive_006087

36. 4-27-00-06328 (beilstein Handbook Reference)

37. Schembl410090

38. Chembl1899506

39. Dtxsid2022626

40. Chebi:135141

41. Tox21_112428

42. Zinc55161150

43. Akos000560001

44. Db13474

45. Cas-5169-78-8

46. Hy-121685

47. Cs-0083052

48. 3-(di-2-thienylmethylidene)-1-methylpiperidine

49. D08604

50. 3-(dithiophen-2-ylmethylene)-1-methylpiperidine

51. A852039

52. Q7808816

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 275.4 g/mol
Molecular Formula C15H17NS2
XLogP33.7
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Exact Mass275.08024189 g/mol
Monoisotopic Mass275.08024189 g/mol
Topological Polar Surface Area59.7 Ų
Heavy Atom Count18
Formal Charge0
Complexity309
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 ATC Code

R - Respiratory system

R05 - Cough and cold preparations

R05D - Cough suppressants, excl. combinations with expectorants

R05DB - Other cough suppressants

R05DB24 - Tipepidine


ABOUT THIS PAGE

Tipepidine Manufacturers

A Tipepidine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Tipepidine, including repackagers and relabelers. The FDA regulates Tipepidine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Tipepidine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Tipepidine Suppliers

A Tipepidine supplier is an individual or a company that provides Tipepidine active pharmaceutical ingredient (API) or Tipepidine finished formulations upon request. The Tipepidine suppliers may include Tipepidine API manufacturers, exporters, distributors and traders.

Tipepidine GMP

Tipepidine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Tipepidine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Tipepidine GMP manufacturer or Tipepidine GMP API supplier for your needs.

Tipepidine CoA

A Tipepidine CoA (Certificate of Analysis) is a formal document that attests to Tipepidine's compliance with Tipepidine specifications and serves as a tool for batch-level quality control.

Tipepidine CoA mostly includes findings from lab analyses of a specific batch. For each Tipepidine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Tipepidine may be tested according to a variety of international standards, such as European Pharmacopoeia (Tipepidine EP), Tipepidine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Tipepidine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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