Find Todralazine manufacturers, exporters & distributors on PharmaCompass

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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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USDMF

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CEP/COS

CEP/COS Certifications

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JDMF

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KDMF

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NDC API

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Other Suppliers

0INTERMEDIATES

REF. STANDARDS OR IMPURITIES

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EDQM

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USP

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PATENTS & EXCLUSIVITIES

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Chemistry

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Also known as: 14679-73-3, Todralacina, Todralazina, Ecarazine, Carboethoxyphthalazinohydrazine, Ethyl 3-(1-phthalazinyl)carbazate
Molecular Formula
C11H12N4O2
Molecular Weight
232.24  g/mol
InChI Key
WGZDBVOTUVNQFP-UHFFFAOYSA-N
FDA UNII
WEN3K83YKD

Todralazine
An antihypertensive agent with both central and peripheral action; it has some central nervous system depressant effects.
1 2D Structure

Todralazine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
ethyl N-(phthalazin-1-ylamino)carbamate
2.1.2 InChI
InChI=1S/C11H12N4O2/c1-2-17-11(16)15-14-10-9-6-4-3-5-8(9)7-12-13-10/h3-7H,2H2,1H3,(H,13,14)(H,15,16)
2.1.3 InChI Key
WGZDBVOTUVNQFP-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCOC(=O)NNC1=NN=CC2=CC=CC=C21
2.2 Other Identifiers
2.2.1 UNII
WEN3K83YKD
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Apirachol

2. Binazin

3. Binazine

4. Ecarazine

5. Todrazoline

2.3.2 Depositor-Supplied Synonyms

1. 14679-73-3

2. Todralacina

3. Todralazina

4. Ecarazine

5. Carboethoxyphthalazinohydrazine

6. Ethyl 3-(1-phthalazinyl)carbazate

7. Bt 621

8. Carbazic Acid, 3-(1-phthalazinyl)-, Ethyl Ester

9. 3-(1-phthalazinyl)carbazic Acid Ethyl Ester

10. Hydrazinecarboxylic Acid, 2-(1-phthalazinyl)-, Ethyl Ester

11. Wen3k83ykd

12. Ceph [as Hydrochloride]

13. Binazin

14. Bt 621 [as Hydrochloride]

15. Nsc-757868

16. Todralacina [spanish]

17. Todralazinum

18. Todralazine [inn:ban]

19. Todralazinum [inn-latin]

20. Todralazina [inn-spanish]

21. Ncgc00016640-03

22. Unii-wen3k83ykd

23. Cas-3778-76-5

24. N-carboethoxy-n'-phthalazino-hydrazine

25. Brn 0233300

26. Todralazine (ban)

27. Ceph

28. Binazine (salt/mix)

29. Ethyl N-(phthalazin-1-ylamino)carbamate

30. Ecarazine (salt/mix)

31. Ceph Free Base

32. Spectrum_001187

33. Todrazoline (salt/mix)

34. Todralazine [mi]

35. Prestwick0_000071

36. Prestwick1_000071

37. Prestwick2_000071

38. Prestwick3_000071

39. Spectrum2_001147

40. Spectrum3_000932

41. Spectrum4_001031

42. Spectrum5_001223

43. Todralazine [inn]

44. Bt-621 Free Base

45. Schembl49644

46. Bspbio_000281

47. Kbiogr_001581

48. Kbioss_001667

49. Todralazine [who-dd]

50. 5-25-17-00414 (beilstein Handbook Reference)

51. Divk1c_000506

52. Spbio_001073

53. Spbio_002202

54. Bpbio1_000311

55. Chembl1079787

56. Dtxsid0045048

57. Chebi:94706

58. Kbio1_000506

59. Kbio2_001667

60. Kbio2_004235

61. Kbio2_006803

62. Kbio3_001964

63. Ninds_000506

64. Hy-b1001

65. Zinc18055768

66. Cs-4498

67. Nsc 757868

68. Idi1_000506

69. Ncgc00016640-01

70. Ncgc00016640-02

71. 1-(n'-ethoxycarbonylhydrazino)phthalazine

72. Da-10133

73. Sbi-0051674.p002

74. Ab00053609

75. Ft-0737585

76. D08613

77. Ethyl 2-(1-phthalazinyl)hydrazinecarboxylate #

78. Ab00053609_08

79. N-(1-phthalazinylamino)carbamic Acid Ethyl Ester

80. Cu-00000000398-1

81. Brd-k68553471-003-04-0

82. Brd-k68553471-003-07-3

83. Q27166508

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 232.24 g/mol
Molecular Formula C11H12N4O2
XLogP31.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Exact Mass232.09602564 g/mol
Monoisotopic Mass232.09602564 g/mol
Topological Polar Surface Area76.1 Ų
Heavy Atom Count17
Formal Charge0
Complexity262
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antihypertensive Agents

Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. (See all compounds classified as Antihypertensive Agents.)


ABOUT THIS PAGE

Looking for 14679-73-3 / Todralazine API manufacturers, exporters & distributors?

Todralazine manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Todralazine API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Todralazine manufacturer or Todralazine supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Todralazine manufacturer or Todralazine supplier.

PharmaCompass also assists you with knowing the Todralazine API Price utilized in the formulation of products. Todralazine API Price is not always fixed or binding as the Todralazine Price is obtained through a variety of data sources. The Todralazine Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Todralazine

Synonyms

14679-73-3, Todralacina, Todralazina, Ecarazine, Carboethoxyphthalazinohydrazine, Ethyl 3-(1-phthalazinyl)carbazate

Cas Number

14679-73-3

Unique Ingredient Identifier (UNII)

WEN3K83YKD

About Todralazine

An antihypertensive agent with both central and peripheral action; it has some central nervous system depressant effects.

Todralazine Manufacturers

A Todralazine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Todralazine, including repackagers and relabelers. The FDA regulates Todralazine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Todralazine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Todralazine Suppliers

A Todralazine supplier is an individual or a company that provides Todralazine active pharmaceutical ingredient (API) or Todralazine finished formulations upon request. The Todralazine suppliers may include Todralazine API manufacturers, exporters, distributors and traders.

Todralazine GMP

Todralazine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Todralazine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Todralazine GMP manufacturer or Todralazine GMP API supplier for your needs.

Todralazine CoA

A Todralazine CoA (Certificate of Analysis) is a formal document that attests to Todralazine's compliance with Todralazine specifications and serves as a tool for batch-level quality control.

Todralazine CoA mostly includes findings from lab analyses of a specific batch. For each Todralazine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Todralazine may be tested according to a variety of international standards, such as European Pharmacopoeia (Todralazine EP), Todralazine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Todralazine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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