Find Tolvaptan Sodium Phosphate manufacturers, exporters & distributors on PharmaCompass

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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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USDMF

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CEP/COS Certifications

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JDMF

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EU WC

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NDC API

NDC API

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VMF

NDC API

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API

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FDF

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Chemistry

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Also known as: D11659
Molecular Formula
C26H24ClN2Na2O6P
Molecular Weight
572.9  g/mol
InChI Key
IHNKFKPPZJVMMZ-PPLJNSMQSA-L

Tolvaptan Sodium Phosphate
1 2D Structure

Tolvaptan Sodium Phosphate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
disodium;[(5R)-7-chloro-1-[2-methyl-4-[(2-methylbenzoyl)amino]benzoyl]-2,3,4,5-tetrahydro-1-benzazepin-5-yl] phosphate
2.1.2 InChI
InChI=1S/C26H26ClN2O6P.2Na/c1-16-6-3-4-7-20(16)25(30)28-19-10-11-21(17(2)14-19)26(31)29-13-5-8-24(35-36(32,33)34)22-15-18(27)9-12-23(22)29;;/h3-4,6-7,9-12,14-15,24H,5,8,13H2,1-2H3,(H,28,30)(H2,32,33,34);;/q;2*+1/p-2/t24-;;/m1../s1
2.1.3 InChI Key
IHNKFKPPZJVMMZ-PPLJNSMQSA-L
2.1.4 Canonical SMILES
CC1=CC=CC=C1C(=O)NC2=CC(=C(C=C2)C(=O)N3CCCC(C4=C3C=CC(=C4)Cl)OP(=O)([O-])[O-])C.[Na+].[Na+]
2.1.5 Isomeric SMILES
CC1=CC=CC=C1C(=O)NC2=CC(=C(C=C2)C(=O)N3CCC[C@H](C4=C3C=CC(=C4)Cl)OP(=O)([O-])[O-])C.[Na+].[Na+]
2.2 Synonyms
2.2.1 Depositor-Supplied Synonyms

1. D11659

2.3 Create Date
2020-05-18
3 Chemical and Physical Properties
Molecular Weight 572.9 g/mol
Molecular Formula C26H24ClN2Na2O6P
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass572.0855897 g/mol
Monoisotopic Mass572.0855897 g/mol
Topological Polar Surface Area122 Ų
Heavy Atom Count38
Formal Charge0
Complexity828
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3

API SUPPLIERS

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01

Shandong Chenghui Shuangda Pharmac...

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothChina's leading API and intermediate manufacturer, offering CMO/CDMO services and exports to 70+ countries, enhancing global health.

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USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
Shandong Chenghui Shuangda Pharmaceutical
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Listed Suppliers

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  • fda
  • EDQM
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Virtual BoothChina's leading API and intermediate manufacturer, offering CMO/CDMO services and exports to 70+ countries, enhancing global health.

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Tolvaptan Sodium Phosphate

About the Company : Shandong Chenghui Shuangda Pharmaceutical Co., Ltd. is specialized in R&D and production of APIs and advanced intermediates. With 22 years of production experience,the company has ...

Shandong Chenghui Shuangda Pharmaceutical Co., Ltd. is specialized in R&D and production of APIs and advanced intermediates. With 22 years of production experience,the company has 6 workshops and 9 production lines which has 100t/month production capacity.The company is committed to maintain the standards with continuous improvements to the current standards throughout the product lifecycle.The main products include local anesthetic drugs, antiviral drugs, cardiovascular and cerebrovascular drugs, antitumor drugs, gastrointestinal drugs, diabetic drugs, veterinary drugs, and CDMO products.
Shandong Chenghui Shuangda Pharmaceutical
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Drugs in Development

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Details:

SAMTASU is a prodrug of oral tolvaptan (generic name is tolvaptan sodium phosphate). A prodrug is a medication that is converted into an active drug in the human body following administration.


Lead Product(s): Tolvaptan Sodium Phosphate

Therapeutic Area: Cardiology/Vascular Diseases Brand Name: Samtasu

Study Phase: ApprovedProduct Type: Small molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 30, 2022

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01

Pharma, Lab & Chemical Expo
Not Confirmed
Pharma, Lab & Chemical Expo
Not Confirmed

Details : SAMTASU is a prodrug of oral tolvaptan (generic name is tolvaptan sodium phosphate). A prodrug is a medication that is converted into an active drug in the human body following administration.

Brand Name : Samtasu

Molecule Type : Small molecule

Upfront Cash : Not Applicable

May 30, 2022

blank

Details:

SAMTASU is a prodrug of oral tolvaptan (generic - tolvaptan sodium phosphate). A prodrug is a medication that is converted into an active drug in the human body. Tolvaptan, discovered by Otsuka, is a novel compound, antagonist of vasopressin V2-receptor.


Lead Product(s): Tolvaptan Sodium Phosphate

Therapeutic Area: Cardiology/Vascular Diseases Brand Name: Samtasu

Study Phase: ApprovedProduct Type: Small molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 28, 2022

blank

02

Pharma, Lab & Chemical Expo
Not Confirmed
Pharma, Lab & Chemical Expo
Not Confirmed

Details : SAMTASU is a prodrug of oral tolvaptan (generic - tolvaptan sodium phosphate). A prodrug is a medication that is converted into an active drug in the human body. Tolvaptan, discovered by Otsuka, is a novel compound, antagonist of vasopressin V2-receptor.

Brand Name : Samtasu

Molecule Type : Small molecule

Upfront Cash : Not Applicable

March 28, 2022

blank
Full Screen ViewFULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

ABOUT THIS PAGE

Tolvaptan Sodium Phosphate Manufacturers

A Tolvaptan Sodium Phosphate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Tolvaptan Sodium Phosphate, including repackagers and relabelers. The FDA regulates Tolvaptan Sodium Phosphate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Tolvaptan Sodium Phosphate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Tolvaptan Sodium Phosphate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Tolvaptan Sodium Phosphate Suppliers

A Tolvaptan Sodium Phosphate supplier is an individual or a company that provides Tolvaptan Sodium Phosphate active pharmaceutical ingredient (API) or Tolvaptan Sodium Phosphate finished formulations upon request. The Tolvaptan Sodium Phosphate suppliers may include Tolvaptan Sodium Phosphate API manufacturers, exporters, distributors and traders.

click here to find a list of Tolvaptan Sodium Phosphate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Tolvaptan Sodium Phosphate GMP

Tolvaptan Sodium Phosphate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Tolvaptan Sodium Phosphate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Tolvaptan Sodium Phosphate GMP manufacturer or Tolvaptan Sodium Phosphate GMP API supplier for your needs.

Tolvaptan Sodium Phosphate CoA

A Tolvaptan Sodium Phosphate CoA (Certificate of Analysis) is a formal document that attests to Tolvaptan Sodium Phosphate's compliance with Tolvaptan Sodium Phosphate specifications and serves as a tool for batch-level quality control.

Tolvaptan Sodium Phosphate CoA mostly includes findings from lab analyses of a specific batch. For each Tolvaptan Sodium Phosphate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Tolvaptan Sodium Phosphate may be tested according to a variety of international standards, such as European Pharmacopoeia (Tolvaptan Sodium Phosphate EP), Tolvaptan Sodium Phosphate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Tolvaptan Sodium Phosphate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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