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1. Ap 12009
2. Ap-2-09
3. Dna, D(p-thio)(c-g-g-c-a-t-g-t-c-t-a-t-t-t-t-g-t-a)
1. Trabedersen [inn:ban]
2. Unii-98oyr854ny
3. 98oyr854ny
4. Ap-2-09
5. Dna, D(p-thio)(c-g-g-c-a-t-g-t-c-t-a-t-t-t-t-g-t-a)
6. 925681-61-4
| Molecular Weight | 5770 g/mol |
|---|---|
| Molecular Formula | C177H226N60O94P17S17+ |
| Hydrogen Bond Donor Count | 42 |
| Hydrogen Bond Acceptor Count | 131 |
| Rotatable Bond Count | 102 |
| Exact Mass | 5766.5573904 g/mol |
| Monoisotopic Mass | 5765.5540356 g/mol |
| Topological Polar Surface Area | 2470 Ų |
| Heavy Atom Count | 365 |
| Formal Charge | 1 |
| Complexity | 15200 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 54 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 2 |
Investigated for use/treatment in brain cancer, colorectal cancer, melanoma, and pancreatic cancer.
Antineoplastic Agents
Substances that inhibit or prevent the proliferation of NEOPLASMS. (See all compounds classified as Antineoplastic Agents.)
AP 12009 is an antisense oligodeoxynucleotide that specifically inhibits TGF-beta2. TGF-beta overexpression is a hallmark of various malignant tumors. This is due to the pivotal role of TGF-beta as it regulates key mechanisms of tumor development, namely immunosuppression, metastasis, angiogenesis, and proliferation.
Drugs in Development
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PharmaCompass offers a list of Trabedersen API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Trabedersen manufacturer or Trabedersen supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Trabedersen manufacturer or Trabedersen supplier.
PharmaCompass also assists you with knowing the Trabedersen API Price utilized in the formulation of products. Trabedersen API Price is not always fixed or binding as the Trabedersen Price is obtained through a variety of data sources. The Trabedersen Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.
A Trabedersen manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Trabedersen, including repackagers and relabelers. The FDA regulates Trabedersen manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Trabedersen API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Trabedersen supplier is an individual or a company that provides Trabedersen active pharmaceutical ingredient (API) or Trabedersen finished formulations upon request. The Trabedersen suppliers may include Trabedersen API manufacturers, exporters, distributors and traders.
Trabedersen Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Trabedersen GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Trabedersen GMP manufacturer or Trabedersen GMP API supplier for your needs.
A Trabedersen CoA (Certificate of Analysis) is a formal document that attests to Trabedersen's compliance with Trabedersen specifications and serves as a tool for batch-level quality control.
Trabedersen CoA mostly includes findings from lab analyses of a specific batch. For each Trabedersen CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Trabedersen may be tested according to a variety of international standards, such as European Pharmacopoeia (Trabedersen EP), Trabedersen JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Trabedersen USP).
