Find Trandolapril Mixture With Verapamil manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: Trandolapril mixture with verapamil, Verapamil mixture with trandolapril, Trandolapril/verapamil hydrochloride er, Trandolapril mixture with verapamil hcl, Trandolapril plus verapamil hydrochloride, Trandolapril-verapamil hydrochloride mixt.
Molecular Formula
C51H73ClN4O9
Molecular Weight
921.6  g/mol
InChI Key
PPAGZPRHIOKKLV-WDFOJNLTSA-N

Trandolapril Mixture With Verapamil
1 2D Structure

Trandolapril Mixture With Verapamil

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S,3aR,7aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid;2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile;hydrochloride
2.1.2 InChI
InChI=1S/C27H38N2O4.C24H34N2O5.ClH/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6;1-3-31-24(30)19(14-13-17-9-5-4-6-10-17)25-16(2)22(27)26-20-12-8-7-11-18(20)15-21(26)23(28)29;/h9-12,17-18,20H,8,13-16H2,1-7H3;4-6,9-10,16,18-21,25H,3,7-8,11-15H2,1-2H3,(H,28,29);1H/t;16-,18+,19-,20-,21-;/m.0./s1
2.1.3 InChI Key
PPAGZPRHIOKKLV-WDFOJNLTSA-N
2.1.4 Canonical SMILES
CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2C3CCCCC3CC2C(=O)O.CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC.Cl
2.1.5 Isomeric SMILES
CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N2[C@H]3CCCC[C@@H]3C[C@H]2C(=O)O.CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC.Cl
2.2 Synonyms
2.2.1 Depositor-Supplied Synonyms

1. Trandolapril Mixture With Verapamil

2. Verapamil Mixture With Trandolapril

3. Trandolapril/verapamil Hydrochloride Er

4. Trandolapril Mixture With Verapamil Hcl

5. Trandolapril Plus Verapamil Hydrochloride

6. Trandolapril-verapamil Hydrochloride Mixt.

7. Trandolapril Mixture With Verapamil Hydrochloride

8. Schembl2526928

9. 146994-90-3

10. 1h-indole-2-carboxylic Acid, 1-((2s)-2-(((1s)-1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydro-, (2s,3ar,7as)-, Mixt. With Alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)benzeneacetonitrile Monohydrochloride

2.3 Create Date
2008-07-11
3 Chemical and Physical Properties
Molecular Weight 921.6 g/mol
Molecular Formula C51H73ClN4O9
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count12
Rotatable Bond Count23
Exact Mass920.5066076 g/mol
Monoisotopic Mass920.5066076 g/mol
Topological Polar Surface Area160 Ų
Heavy Atom Count65
Formal Charge0
Complexity1240
Isotope Atom Count0
Defined Atom Stereocenter Count5
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Drug and Medication Information
4.1 Drug Information
1 of 1  
Drug NameTRANDOLAPRIL AND VERAPAMIL HYDROCHLORIDE
Active IngredientTRANDOLAPRIL; VERAPAMIL HYDROCHLORIDE
CompanyGLENMARK GENERICS (Application Number: A079135)

5 Pharmacology and Biochemistry
5.1 FDA Pharmacological Classification
5.1.1 Pharmacological Classes
Angiotensin-converting Enzyme Inhibitors [MoA]; Calcium Channel Antagonists [MoA]; Calcium Channel Blocker [EPC]; Cytochrome P450 3A Inhibitors [MoA]; Cytochrome P450 3A4 Inhibitors [MoA]; P-Glycoprotein Inhibitors [MoA]; Angiotensin Converting Enzyme Inhibitor [EPC]

DRUG PRODUCT COMPOSITIONS

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DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 1MG;...DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 1MG;240MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

USFDA APPLICATION NUMBER - 20591

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DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 2MG;...DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 2MG;180MG

USFDA APPLICATION NUMBER - 20591

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DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 2MG;...DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 2MG;240MG

USFDA APPLICATION NUMBER - 20591

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DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 4MG;...DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 4MG;240MG

USFDA APPLICATION NUMBER - 20591

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ABOUT THIS PAGE

Trandolapril Mixture With Verapamil Manufacturers

A Trandolapril Mixture With Verapamil manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Trandolapril Mixture With Verapamil, including repackagers and relabelers. The FDA regulates Trandolapril Mixture With Verapamil manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Trandolapril Mixture With Verapamil API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Trandolapril Mixture With Verapamil Suppliers

A Trandolapril Mixture With Verapamil supplier is an individual or a company that provides Trandolapril Mixture With Verapamil active pharmaceutical ingredient (API) or Trandolapril Mixture With Verapamil finished formulations upon request. The Trandolapril Mixture With Verapamil suppliers may include Trandolapril Mixture With Verapamil API manufacturers, exporters, distributors and traders.

Trandolapril Mixture With Verapamil GMP

Trandolapril Mixture With Verapamil Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Trandolapril Mixture With Verapamil GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Trandolapril Mixture With Verapamil GMP manufacturer or Trandolapril Mixture With Verapamil GMP API supplier for your needs.

Trandolapril Mixture With Verapamil CoA

A Trandolapril Mixture With Verapamil CoA (Certificate of Analysis) is a formal document that attests to Trandolapril Mixture With Verapamil's compliance with Trandolapril Mixture With Verapamil specifications and serves as a tool for batch-level quality control.

Trandolapril Mixture With Verapamil CoA mostly includes findings from lab analyses of a specific batch. For each Trandolapril Mixture With Verapamil CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Trandolapril Mixture With Verapamil may be tested according to a variety of international standards, such as European Pharmacopoeia (Trandolapril Mixture With Verapamil EP), Trandolapril Mixture With Verapamil JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Trandolapril Mixture With Verapamil USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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