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Tranylcypromine Sulfate

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ACTIVE PHARMA INGREDIENTS

9 API Suppliers, 6 USDMF, 1 EU WC, 2 NDC API, 5 Listed Suppliers, $ API Reference Price

9 API Suppliers
6 USDMF
1 EU WC
2 NDC API
5 Listed Suppliers
$ API Reference Price

FINISHED DOSAGE FORMULATIONS

12 FDF Dossiers, 4 FDA Orange Book, 1 Europe, 1 Canada, 1 Australia, 1 South Africa, 4 Listed Dossiers

12 FDF Dossiers
4 FDA Orange Book
1 Europe
1 Canada
1 Australia
1 South Africa
4 Listed Dossiers

RELATED EXCIPIENT COMPANIES

1 SPI Pharma, 7 DKSH, 2 Faran Shimi Pharmaceutical, 7 Gangwal Healthcare, 2 Nanjing Well Pharmaceutical, 4 ACG Worldwide, 1 Aeon Procare, 5 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 3 BASF, 1 Clariant, 5 Corel Pharma Chem, 3 DFE Pharma, 7 Gangwal Chemicals, 3 Ideal Cures Pvt Ltd, 1 Ingredion Pharma Solutions, 8 Kerry, 3 Lonza Capsugel, 7 Microlex e.U, 1 Novo Excipients, 1 Pharmatrans-Sanaq, 2 Pluviaendo, 3 Prachin Chemical, 1 Qualicaps, 11 Roquette, 3 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 10 Sigachi Industries, 3 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

28 Fillers, Diluents & Binders, 22 Coating Systems & Additives, 16 Direct Compression, 16 Thickeners and Stabilizers, 15 Disintegrants & Superdisintegrants, 14 Lubricants & Glidants, 10 Controlled & Modified Release, 10 Co-Processed Excipients, 9 Granulation, 8 Empty Capsules, 6 Film Formers & Plasticizers, 4 Topical, 3 Rheology Modifiers, 3 Emulsifying Agents, 3 Parenteral, 3 Taste Masking, 2 Coloring Agents, 2 Chewable & Orodispersible Aids, 2 API Stability Enhancers, 1 Surfactant & Foaming Agents

DIGITAL CONTENT

2 NEWS #PharmaBuzz

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GLOBAL SALES INFORMATION

2 US Medicaid Prescriptions, 2 Finished Drug Prices

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2 US Medicaid Prescriptions
2 Finished Drug Prices

MARKET PLACE

1 APIs

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1 APIs

REF. STANDARDS & IMPURITIES

3 USP , 3 Others

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3 USP
3 Others

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 3,863

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

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US Patents

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Health Canada Patents

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GLOBAL SALES INFORMATION

US Medicaid (USD)

4,913,860

Annual Reports (USD Million)

Finished Drug Prices

105 RELATED EXCIPIENT COMPANIES

177EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: Tranylcypromine sulfate, 13492-01-8, Tranylcypromine sulfate (usp), Chebi:9653, D00826

Molecular Formula

C₁₈H₂₄N₂O₄S

Molecular Weight

364.5 g/mol

InChI Key

BKPRVQDIOGQWTG-VYIKEJMZSA-N

A propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders. (From AMA Drug Evaluations Annual, 1994, p311)

1 2D Structure

Tranylcypromine Sulfate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(1R)-2-phenylcyclopropan-1-amine;sulfuric acid

2.1.2 InChI

InChI=1S/2C9H11N.H2O4S/c2*10-9-6-8(9)7-4-2-1-3-5-7;1-5(2,3)4/h2*1-5,8-9H,6,10H2;(H2,1,2,3,4)/t2*8?,9-;/m11./s1

2.1.3 InChI Key

BKPRVQDIOGQWTG-VYIKEJMZSA-N

2.1.4 Canonical SMILES

C1C(C1N)C2=CC=CC=C2.C1C(C1N)C2=CC=CC=C2.OS(=O)(=O)O

2.1.5 Isomeric SMILES

C1[C@H](C1C2=CC=CC=C2)N.C1[C@H](C1C2=CC=CC=C2)N.OS(=O)(=O)O

2.2 Synonyms

2.2.1 MeSH Synonyms

1. Jatrosom

2. Parnate

3. Sulfate, Tranylcypromine

4. Trans 2 Phenylcyclopropylamine

5. Trans-2-phenylcyclopropylamine

6. Transamine

7. Tranylcypromine

8. Tranylcypromine Sulfate

2.2.2 Depositor-Supplied Synonyms

1. Tranylcypromine Sulfate

2. 13492-01-8

3. Tranylcypromine Sulfate (usp)

4. Chebi:9653

5. D00826

2.3 Create Date

2008-02-08

3 Chemical and Physical Properties

Molecular Formula	C₁₈H₂₄N₂O₄S
Molecular Weight	364.5 g/mol
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	2
Exact Mass	364.14567842 g/mol
Monoisotopic Mass	364.14567842 g/mol
Topological Polar Surface Area	135 Å²
Heavy Atom Count	25
Formal Charge	0
Complexity	197
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	2
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	3

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Anti-Anxiety Agents

Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here. (See all compounds classified as Anti-Anxiety Agents.)

Antidepressive Agents

Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems. (See all compounds classified as Antidepressive Agents.)

Monoamine Oxidase Inhibitors

A chemically heterogeneous group of drugs that have in common the ability to block oxidative deamination of naturally occurring monoamines. (From Gilman, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p414) (See all compounds classified as Monoamine Oxidase Inhibitors.)

4.2 FDA Pharmacological Classification

4.2.1 Pharmacological Classes

Monoamine Oxidase Inhibitors [MoA]; Monoamine Oxidase Inhibitor [EPC]

API SUPPLIERS

01

Nuray Chemicals Private Limited

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering

Not Confirmed

Nuray is an expert in the synthesis of Niche novel APIs, the first to launch Generics, NCEs, Advanced Intermediates // USFDA certified.

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India

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USDMF

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CEP/COS JDMF EU-WC NDC

KDMF VMF Others AUDIT

02

HRV Global Life Sciences

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering

Not Confirmed

HRV Global Life Sciences - Market Expansion Leader in Pharmaceuticals.

Contact Supplier

India

Virtual Booth

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USDMF CEP/COS JDMF EU-WC NDC KDMF VMF AU

AUDIT

03

Trifarma

Italy

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering

Not Confirmed

04

Lonza Group

Switzerland

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering

Not Confirmed

05

GSK

United Kingdom

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering

Not Confirmed

09

Optimus Pharma

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering

Not Confirmed

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USDMF

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EU WC

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NDC API

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Listed Suppliers

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API Reference Price

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OF","selfForZScoreResived":"Pharma Grade","supplierPort":"MADRAS AIR","supplierAddress":"25, 12TH CROSS STREET, SHASTRI NAGAR,, CHENNAI\/TAMILNADU","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1673289000,"product":"TRANYLCYPROMINE SULFATE USP","address":"25, 12TH CROSS STREET, SHASTRI NAGAR,","city":"CHENNAI\/TAMILNADU","supplier":"NURAY CHEMICALS PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"HO CHI MINH C","customer":"THE PURCHASE MANAGER","customerCountry":"VIETNAM","quantity":"0.05","actualQuantity":"0.05","unit":"KGS","unitRateFc":"25000","totalValueFC":"1235.3","currency":"USD","unitRateINR":2020000,"date":"10-Jan-2023","totalValueINR":"101000","totalValueInUsd":"1235.3","indian_port":"MADRAS AIR","hs_no":"29339990","bill_no":"6856428","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"VIETNAM, DEMOCRATIC REP. 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MAHARASHTRA","supplier":"TRIFARMA","supplierCountry":"ITALY","foreign_port":"MILAN - MALPENSA","customer":"GLENMARK PHARMACEUTICALS","customerCountry":"INDIA","quantity":"4.94","actualQuantity":"4.944","unit":"KGS","unitRateFc":"5350","totalValueFC":"26709.6","currency":"USD","unitRateINR":"453947.5","date":"05-Oct-2024","totalValueINR":"2244316.44","totalValueInUsd":"26709.6","indian_port":"Bombay Air","hs_no":"29214990","bill_no":"5963637","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"MILAN - MALPENSA","supplierAddress":"VIA GUIDO GUARINI MATTEUCCI,120162 MILANO. SDNF ITALY","customerAddress":"B\/2 MAHALAXMI CHAMBERS"}]

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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FDF Dossiers

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FDA Orange Book

01

STRIDES PHARMA

India

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RLD : No

TE Code : AB

TRANYLCYPROMINE SULFATE

Brand Name : TRANYLCYPROMINE SULFATE

Dosage Form : TABLET;ORAL

Dosage Strength : EQ 10MG BASE

Approval Date : 2006-06-29

Application Number : 40640

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

02

CONCORDIA

United Kingdom

Antibody Engineering

Not Confirmed

03

NOVITIUM PHARMA

U.S.A

Antibody Engineering

Not Confirmed

04

CROSSMEDIKA SA

Country

Antibody Engineering

Not Confirmed

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Europe

01

SIT LABORATORIO FARMAC. Srl

Country

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Not Confirmed

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Canada

01

GLAXOSMITHKLINE INC

Antibody Engineering

Not Confirmed

Strides Pharma Science: Pioneering IP-driven formulations for niche finished dosage forms.

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India

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Regulatory Info :

Registration Country : India

Tranylcypromine Sulfate

Brand Name :

Dosage Form : Tablet

Dosage Strength : 10MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

02

Neuraxpharm

Spain

Antibody Engineering

Not Confirmed

03

Neuraxpharm

Spain

Antibody Engineering

Not Confirmed

04

Neuraxpharm

Spain

Antibody Engineering

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Disintegrants & Superdisintegrants

Lubricants & Glidants

Controlled & Modified Release

Co-Processed Excipients

Granulation

Empty Capsules

Film Formers & Plasticizers

Topical

Rheology Modifiers

Emulsifying Agents

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NEWS #PharmaBuzz

Kinedexe’s Generic Tranylcypromine Sulfate Receives Approval In US

20 Apr 2018

// FDA

Duchesnay USA Announces Launch Bonjesta®doxylamine succinate, pyridoxine HCL)

02 Apr 2018

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Finished Drug Prices

01

Brand Name : TRANYLCYPROMINE SULFATE

India

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India

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RX/OTC/DISCN : RX

STRIDES PHARMA

Tranylcypromine Sulfate

Dosage Form : TABLET;ORAL

Dosage Strength : EQ 10MG BASE

Price Per Pack :

Published in :

Country : USA

RX/OTC/DISCN : RX

02

Brand Name : Parmodalin

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ACTIVE PHARMA INGREDIENTS

9 API Suppliers

6 USDMF

1 EU WC

2 NDC API

5 Listed Suppliers

$ API Reference Price

FINISHED DOSAGE FORMULATIONS

12 FDF Dossiers

4 FDA Orange Book

1 Europe

1 Canada

1 Australia

1 South Africa

4 Listed Dossiers

RELATED EXCIPIENT COMPANIES

1 SPI Pharma

7 DKSH

2 Faran Shimi Pharmaceutical

7 Gangwal Healthcare

2 Nanjing Well Pharmaceutical

4 ACG Worldwide

1 Aeon Procare

5 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

3 BASF

1 Clariant

5 Corel Pharma Chem

3 DFE Pharma

7 Gangwal Chemicals

3 Ideal Cures Pvt Ltd

1 Ingredion Pharma Solutions

8 Kerry

3 Lonza Capsugel

7 Microlex e.U

1 Novo Excipients

1 Pharmatrans-Sanaq

2 Pluviaendo

3 Prachin Chemical

1 Qualicaps

11 Roquette

3 Shanghai Shenmei Pharmaceutical Technology Co., Ltd

10 Sigachi Industries

3 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

28 Fillers, Diluents & Binders

22 Coating Systems & Additives

16 Direct Compression

16 Thickeners and Stabilizers

15 Disintegrants & Superdisintegrants

14 Lubricants & Glidants

10 Controlled & Modified Release

10 Co-Processed Excipients

9 Granulation

8 Empty Capsules

6 Film Formers & Plasticizers

4 Topical

3 Rheology Modifiers

3 Emulsifying Agents

3 Parenteral

3 Taste Masking

2 Coloring Agents

2 Chewable & Orodispersible Aids

2 API Stability Enhancers

1 Surfactant & Foaming Agents

DIGITAL CONTENT

2 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

2 US Medicaid Prescriptions

2 Finished Drug Prices

MARKET PLACE

1 APIs

REF. STANDARDS & IMPURITIES

3 USP

3 Others

ACTIVE PHARMA INGREDIENTS