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Trazodone Hydrochloride

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ACTIVE PHARMA INGREDIENTS

44 API Suppliers, 20 USDMF, 9 CEP/COS, 2 JDMF, 4 EU WC, 2 KDMF, 18 NDC API, 28 Listed Suppliers, $ API Reference Price

44 API Suppliers
20 USDMF
9 CEP/COS
2 JDMF
4 EU WC
2 KDMF
18 NDC API
28 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

3 Drugs in Development

3 Drugs in Development

INTERMEDIATES

25 Intermediates Suppliers

25 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

165 FDF Dossiers, 68 FDA Orange Book, 31 Europe, 24 Canada, 12 South Africa, 30 Listed Dossiers

165 FDF Dossiers
68 FDA Orange Book
31 Europe
24 Canada
12 South Africa
30 Listed Dossiers

RELATED EXCIPIENT COMPANIES

4 SPI Pharma, 2 Seqens, 3 DKSH, 5 Faran Shimi Pharmaceutical, 1 Boai NKY Pharmaceuticals Ltd, 12 Gangwal Healthcare, 2 Nanjing Well Pharmaceutical, 1 ACG Worldwide, 5 Actylis, 6 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 23 BASF, 10 Corel Pharma Chem, 6 DFE Pharma, 1 Finar, 10 Gangwal Chemicals, 5 Ideal Cures Pvt Ltd, 3 Ingredion Pharma Solutions, 35 Kerry, 3 Kima Chemical, 6 Lonza Capsugel, 12 Microlex e.U, 1 Nanjing Bold Chemical, 2 Nomisma Healthcare, 2 Novo Excipients, 3 Pharmatrans-Sanaq, 5 Pluviaendo, 3 Prachin Chemical, 1 Qianhao Chemical (Hebei) Co., Ltd, 1 Qualicaps, 17 Roquette, 13 Seppic, 4 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 10 Sigachi Industries, 2 The Dow Chemical Company, 3 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

66 Fillers, Diluents & Binders, 46 Coating Systems & Additives, 33 Direct Compression, 28 Controlled & Modified Release, 22 Granulation, 21 Solubilizers, 21 Thickeners and Stabilizers, 20 Disintegrants & Superdisintegrants, 16 Co-Processed Excipients, 14 Lubricants & Glidants, 11 Topical, 10 Parenteral, 10 Film Formers & Plasticizers, 9 Taste Masking, 7 Emulsifying Agents, 6 Chewable & Orodispersible Aids, 5 Empty Capsules, 5 API Stability Enhancers, 4 Coloring Agents, 4 Vegetarian Capsules, 3 Rheology Modifiers, 3 Surfactant & Foaming Agents

DIGITAL CONTENT

1 DATA COMPILATION #PharmaFlow, 11 NEWS #PharmaBuzz

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1 DATA COMPILATION #PharmaFlow
11 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions, 42 Finished Drug Prices

globalSalesInformation
1 US Medicaid Prescriptions
42 Finished Drug Prices

MARKET PLACE

10 APIs, 5 FDF Dossiers

marketPlace
10 APIs
5 FDF Dossiers

PATENTS & EXCLUSIVITIES

8 US Patents

patents
8 US Patents

REF. STANDARDS & IMPURITIES

1 USP , 10 Others

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1 USP
10 Others

Granules Trazodone Hydrochloride

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 124

MARKET PLACE

API

FDF

25INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

165

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

3DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

201,225,023

Annual Reports (USD Million)

Finished Drug Prices

222 RELATED EXCIPIENT COMPANIES

364EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 25332-39-2, Trazodone hcl, Desyrel, Bimaran, Molipaxin, Thombran

Molecular Formula

C₁₉H₂₃Cl₂N₅O

Molecular Weight

408.3 g/mol

InChI Key

OHHDIOKRWWOXMT-UHFFFAOYSA-N

FDA UNII

6E8ZO8LRNM

A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)

1 2D Structure

Trazodone Hydrochloride

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one;hydrochloride

2.1.2 InChI

InChI=1S/C19H22ClN5O.ClH/c20-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-4-10-25-19(26)24-9-2-1-7-18(24)21-25;/h1-3,5-7,9,15H,4,8,10-14H2;1H

2.1.3 InChI Key

OHHDIOKRWWOXMT-UHFFFAOYSA-N

2.1.4 Canonical SMILES

C1CN(CCN1CCCN2C(=O)N3C=CC=CC3=N2)C4=CC(=CC=C4)Cl.Cl

2.2 Other Identifiers

2.2.1 UNII

6E8ZO8LRNM

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Af 1161

2. Af-1161

3. Af1161

4. Apo Trazodone

5. Apo-trazodone

6. Deprax

7. Desyrel

8. Gen Trazodone

9. Gen-trazodone

10. Molipaxin

11. Novo Trazodone

12. Novo-trazodone

13. Nu Trazodone

14. Nu-trazodone

15. Pms Trazodone

16. Pms-trazodone

17. Ratio Trazodone

18. Ratio-trazodone

19. Ratiotrazodone

20. Thombran

21. Tradozone

22. Trazodon Hexal

23. Trazodon Neuraxpharm

24. Trazodon-neuraxpharm

25. Trazodone

26. Trazodonneuraxpharm

27. Trazon

28. Trittico

2.3.2 Depositor-Supplied Synonyms

1. 25332-39-2

2. Trazodone Hcl

3. Desyrel

4. Bimaran

5. Molipaxin

6. Thombran

7. Trazodone (hydrochloride)

8. Af-1161

9. Trialodine

10. Kb-831

11. Oleptro

12. 19666-36-5

13. 6e8zo8lrnm

14. 2-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2h)-one Hydrochloride

15. Nsc-292811

16. Af-1161 (free Base)

17. 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one Hydrochloride

18. 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one;hydrochloride

19. Mls000069698

20. Chebi:9655

21. 1,2,4-triazolo[4,3-a]pyridin-3(2h)-one,2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-,hydrochloride (1:1)

22. 2-(3-(4-(m-chlorophenyl)-1-piperazinyl)propyl)-s-triazolo(4,3-a)pyridin-3(2h)-one Monohydrochloride

23. Trazodone Hydrochloride (desyrel)

24. 1,2,4-triazolo(4,3-a)pyridin-3(2h)-one, 2-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-, Monohydrochloride

25. Devidon

26. Pragmazone

27. Smr000058520

28. Tombran

29. Tritico

30. Triticum

31. Azona

32. 25332-39-2 (hcl)

33. Apo-trazodone

34. Dsstox_cid_24626

35. Dsstox_rid_80361

36. Dsstox_gsid_44626

37. 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2h)-one Hydrochloride

38. Desyrel Dividose

39. 2-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)-1,2,4-triazolo(4,3-a)pyridin-3(2h)-one Hydrochloride

40. 2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-2h,3h-[1,2,4]triazolo[4,3-a]pyridin-3-one Hydrochloride

41. Sr-01000000190

42. Ncgc00016035-02

43. Einecs 246-855-5

44. Unii-6e8zo8lrnm

45. Cas-25332-39-2

46. Nsc 292811

47. Af 1161

48. Trazodone, Hcl

49. 2-[3-[4-(m-chlorophenyl)-1-piperazinyl]propyl]-s-triazolo[4,3-a]pyridin-3(2h)-one Monohydrochloride

50. Prestwick_478

51. Desyrel (tn)

52. Einecs 243-216-2

53. Trazodone Hydrochloride [usan:usp:jan]

54. 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,5-a]pyridin-3-one

55. Opera_id_850

56. Schembl61754

57. 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2h)-one Hydrochloride

58. Mls000758230

59. Mls001148260

60. Mls001424009

61. Spectrum1503121

62. Chembl1200798

63. Dtxsid8044626

64. Hms1568l06

65. Hms1922g09

66. Pharmakon1600-01503121

67. Trazodone Hydrochloride (jan/usp)

68. Bcp04922

69. Hy-b0478

70. Tox21_110286

71. Tox21_302685

72. Tox21_501159

73. Trazodone Hydrochloride [mi]

74. Ccg-40299

75. Nsc292811

76. Nsc758393

77. Trazodone Hydrochloride [jan]

78. Trazodone Hydrochloride [hsdb]

79. Trazodone Hydrochloride [usan]

80. Akos015897762

81. Tox21_110286_1

82. Ac-6779

83. Ks-5100

84. Lp01159

85. Nc00046

86. Nsc-758393

87. Trazodone Hydrochloride [mart.]

88. Trazodone Hydrochloride [vandf]

89. Trazodone Hydrochloride [usp-rs]

90. Trazodone Hydrochloride [who-dd]

91. Trazodone Hydrochloride Impurity Standard

92. Ncgc00016035-13

93. Ncgc00094420-01

94. Ncgc00094420-02

95. Ncgc00094420-03

96. Ncgc00094420-04

97. Ncgc00256807-01

98. Ncgc00261844-01

99. 2-(3-(4-(3-chlorophenyl)piperazin-1-y)propyl)-1,2,4-triazolo(4,3-a)pyridine-3(2h)-one Hydrochloride

100. S-triazolo(4,3-a)pyridin-3(2h)-one, 2-(3-(4-(m-chlorophenyl)-1-piperazinyl)propyl)-, Monohydrochloride

101. Eu-0101159

102. Ft-0659024

103. Ft-0675364

104. S2582

105. Trazodone Hydrochloride [orange Book]

106. D00820

107. D97808

108. T 6154

109. Trazodone Hydrochloride [usp Monograph]

110. Trazodone Hydrochloride, >=99% (hplc), Powder

111. 332t392

112. A813950

113. A817789

114. A924854

115. 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-

116. J-015941

117. Sr-01000000190-2

118. Sr-01000000190-8

119. Wln: T56 Anvnnj C3- At6n Dntj Dr Cg &gh

120. Q27108459

121. 1,2,4-triazolo[4,3-a]pyridin-3(2h)-one Hydrochloride

122. Z1550675462

123. Trazodone Hydrochloride 1.0 Mg/ml In Methanol (as Free Base)

124. Trazodone Hydrochloride, United States Pharmacopeia (usp) Reference Standard

125. S-triazolo[4, 2-[3-[4-(m-chlorophenyl)-1-piperazinyl]propyl]-, Monohydrochloride

126. S-trizolo[4, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-, Hydrochloride

127. 1,2,4-triazolo[4,3-a]pyridin-3(2h)-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-, Hydrochloride (1:1)

128. 1,4-triazolo[4,3-a]pyridin-3(2h)-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-, Monohydrochloride

129. 2-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2h)-onehydrochloride

130. 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one Hydrochloride

131. 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one;hydron;chloride

132. 2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}[1,2,4]triazolo[4,3-a]pyridin-3(2h)-one Hydrochloride

133. Trazodone Hydrochloride Solution, 1.0 Mg/ml In Methanol (as Free Base), Ampule Of 1 Ml, Certified Reference Material

2.4 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₁₉H₂₃Cl₂N₅O
Molecular Weight	408.3 g/mol
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	5
Exact Mass	407.1279658 g/mol
Monoisotopic Mass	407.1279658 g/mol
Topological Polar Surface Area	42.4 Å²
Heavy Atom Count	27
Formal Charge	0
Complexity	611
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 4
Drug Name	Oleptro
PubMed Health	Trazodone (By mouth)
Drug Classes	Antidepressant
Drug Label	Oleptro (trazodone hydrochloride) is a triazolopyridine. It is a white, odorless crystalline powder which is freely soluble in water.Chemical Name: 2-[3-[4-(m-Chlorophenyl)-1-piperazinyl]propyl]-s-triazolo[4,3-a]pyridin-3(2H)-one monohydrochloride St...
Active Ingredient	Trazodone hydrochloride
Dosage Form	Tablet, extended release
Route	Oral
Strength	150mg; 300mg
Market Status	Prescription
Company	Angelini Pharma

2 of 4
Drug Name	Trazodone hydrochloride
Drug Label	Trazodone HCl is an antidepressant chemically unrelated to tricyclic, tetracyclic, or other known antidepressant agents. Trazodone HCl is a triazolopyridine derivative designated as 2-[3-[4-(m-Chlorophenyl)-1-piperazinyl]propyl]s-triazolo[4,3-a]-pyri...
Active Ingredient	Trazodone hydrochloride
Dosage Form	Tablet
Route	Oral
Strength	150mg; 300mg; 100mg; 50mg
Market Status	Prescription
Company	Mylan Pharms; Apotex; Teva Pharms Usa; Torrent Pharms; Mutual Pharm; Vintage; Alvogen; Pliva

3 of 4
Drug Name	Oleptro
PubMed Health	Trazodone (By mouth)
Drug Classes	Antidepressant
Drug Label	Oleptro (trazodone hydrochloride) is a triazolopyridine. It is a white, odorless crystalline powder which is freely soluble in water.Chemical Name: 2-[3-[4-(m-Chlorophenyl)-1-piperazinyl]propyl]-s-triazolo[4,3-a]pyridin-3(2H)-one monohydrochloride St...
Active Ingredient	Trazodone hydrochloride
Dosage Form	Tablet, extended release
Route	Oral
Strength	150mg; 300mg
Market Status	Prescription
Company	Angelini Pharma

4 of 4
Drug Name	Trazodone hydrochloride
Drug Label	Trazodone HCl is an antidepressant chemically unrelated to tricyclic, tetracyclic, or other known antidepressant agents. Trazodone HCl is a triazolopyridine derivative designated as 2-[3-[4-(m-Chlorophenyl)-1-piperazinyl]propyl]s-triazolo[4,3-a]-pyri...
Active Ingredient	Trazodone hydrochloride
Dosage Form	Tablet
Route	Oral
Strength	150mg; 300mg; 100mg; 50mg
Market Status	Prescription
Company	Mylan Pharms; Apotex; Teva Pharms Usa; Torrent Pharms; Mutual Pharm; Vintage; Alvogen; Pliva

4.2 Drug Indication

Treatment of insomnia

5 Pharmacology and Biochemistry

5.1 MeSH Pharmacological Classification

Anti-Anxiety Agents

Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here. (See all compounds classified as Anti-Anxiety Agents.)

Antidepressive Agents, Second-Generation

A structurally and mechanistically diverse group of drugs that are not tricyclics or monoamine oxidase inhibitors. The most clinically important appear to act selectively on serotonergic systems, especially by inhibiting serotonin reuptake. (See all compounds classified as Antidepressive Agents, Second-Generation.)

Selective Serotonin Reuptake Inhibitors

Compounds that specifically inhibit the reuptake of serotonin in the brain. (See all compounds classified as Selective Serotonin Reuptake Inhibitors.)

5.2 FDA Pharmacological Classification

5.2.1 Pharmacological Classes

Serotonin Reuptake Inhibitor [EPC]

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API Reference Price

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D6 D8, SY.NO. 234\/2,234\/3,","city":"TURKAPALLY(V),SHAMEERPET, HYDERABAD","supplier":"UNITED STATES PHARMACOPEIAL","supplierCountry":"INDIA","foreign_port":"WASHINGTON, DULLES I","customer":"UNITED STATES PHARMACOPEIA - INDIA PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.0004","unit":"KGS","unitRateFc":"1365000","totalValueFC":"586.7","currency":"USD","unitRateINR":"123238325","date":"30-Oct-2024","totalValueINR":"49295.33","totalValueInUsd":"586.7","indian_port":"Hyderabad Air","hs_no":"29335990","bill_no":"6422250","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"WASHINGTON, DULLES I","supplierAddress":"7135 ENGLISH MUFFIN WAY FREDERICK, MD, US 21704, UNITED STATES OF AMER ICA United States","customerAddress":"P.NO. D6 D8, SY.NO. 234\/2,234\/3,"}]

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

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Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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Drugs in Development

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INTERMEDIATES SUPPLIERS

01

PMC Isochem

France

Duphat

Not Confirmed

PMC Isochem is your partner for smart CDMOs of Intermediates, APIs, & excipients & a catalog of Intermediates & Generic APIs.

1-(3-chlorophenyl)-4-(3-chloropropyl) piperazine, ...

CAS Number : 52605-52-4

End Use API : Trazodone Hydrochloride

Product Web Link

02

Allchem Laboratories

India

Duphat

Not Confirmed

Not Confirmed

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FDF Dossiers

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FDA Orange Book

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Europe

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Canada

01

APOTEX INC

Canada

Pharma, Lab & Chemical Expo

Not Confirmed

02

JAMP PHARMA CORPORATION

Canada

Pharma, Lab & Chemical Expo

Not Confirmed

03

Pharmascience Inc.

Canada

Canada

Pharma, Lab & Chemical Expo

Not Confirmed

09

SANIS HEALTH INC

Canada

Pharma, Lab & Chemical Expo

Not Confirmed

10

TEVA CANADA LIMITED

Israel

Pharma, Lab & Chemical Expo

Not Confirmed

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South Africa

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Listed Dossiers

01

Granules India Limited

India

Biotech Showcase

Not Confirmed

Granules India Limited has high volume world-class facilities for APIs, PFIs, & FDFs, serving customers in over 80 countries.

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India

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Digital Content

Regulatory Info : ROW, US, EU

Registration Country : India

Trazodone Hydrochloride

Brand Name :

Dosage Form : Immediate Release Tabl...

Dosage Strength : 50MG

Packaging :

Approval Date :

Application Number :

Regulatory Info : ROW, US, EU

Registration Country : India

02

Granules India Limited

India

Biotech Showcase

Not Confirmed

Granules India Limited has high volume world-class facilities for APIs, PFIs, & FDFs, serving customers in over 80 countries.

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India

Virtual Booth

Digital Content

Regulatory Info : ROW, US, EU

Registration Country : India

Trazodone Hydrochloride

Brand Name :

Dosage Form : Immediate Release Tabl...

Dosage Strength : 100MG

Packaging :

Approval Date :

Application Number :

Regulatory Info : ROW, US, EU

Registration Country : India

03

Granules India Limited

India

Biotech Showcase

Not Confirmed

Granules India Limited has high volume world-class facilities for APIs, PFIs, & FDFs, serving customers in over 80 countries.

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India

Virtual Booth

Digital Content

Regulatory Info : ROW, US, EU

Registration Country : India

Trazodone Hydrochloride

Brand Name :

Dosage Form : Immediate Release Tabl...

Dosage Strength : 150MG

Packaging :

Approval Date :

Application Number :

Regulatory Info : ROW, US, EU

Registration Country : India

04

Granules India Limited

India

Biotech Showcase

Not Confirmed

Granules India Limited has high volume world-class facilities for APIs, PFIs, & FDFs, serving customers in over 80 countries.

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India

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Regulatory Info : ROW, US, EU

Registration Country : India

Trazodone Hydrochloride

Brand Name :

Dosage Form : Immediate Release Tabl...

Dosage Strength : 300MG

Packaging :

Approval Date :

Application Number :

Regulatory Info : ROW, US, EU

Registration Country : India

05

Athena Pharmaceutiques

France

Biotech Showcase

Not Confirmed

Athena Pharmaceutiques is a Partner of Choice for Drug Delivery & Life Cycle Management.

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France

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Digital Content

Regulatory Info :

Registration Country : France

Trazodone

Brand Name :

Dosage Form : Sustained Release Tabl...

Dosage Strength : 300MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : France

06

Athena Pharmaceutiques

France

Biotech Showcase

Not Confirmed

Athena Pharmaceutiques is a Partner of Choice for Drug Delivery & Life Cycle Management.

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France

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Digital Content

Regulatory Info :

Registration Country : France

Trazodone

Brand Name :

Dosage Form : Sustained Release Tabl...

Dosage Strength : 150MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : France

07

Strides Pharma Science

India

Biotech Showcase

Not Confirmed

Strides Pharma Science: Pioneering IP-driven formulations for niche finished dosage forms.

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India

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Regulatory Info :

Registration Country : India

Trazodone Hydrochloride

Brand Name :

Dosage Form : Tablet

Dosage Strength : 50MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

08

Strides Pharma Science

India

Biotech Showcase

Not Confirmed

Strides Pharma Science: Pioneering IP-driven formulations for niche finished dosage forms.

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India

Virtual Booth

Digital Content

Regulatory Info :

Registration Country : India

Trazodone Hydrochloride

Brand Name :

Dosage Form : Tablet

Dosage Strength : 100MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

09

Strides Pharma Science

India

Biotech Showcase

Not Confirmed

Strides Pharma Science: Pioneering IP-driven formulations for niche finished dosage forms.

Contact Supplier

India

Virtual Booth

Digital Content

Regulatory Info :

Registration Country : India

Trazodone Hydrochloride

Brand Name :

Dosage Form : Tablet

Dosage Strength : 150MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

10

Strides Pharma Science

India

Biotech Showcase

Not Confirmed

Strides Pharma Science: Pioneering IP-driven formulations for niche finished dosage forms.

Contact Supplier

India

Virtual Booth

Digital Content

Regulatory Info :

Registration Country : India

Trazodone Hydrochloride

Brand Name :

Dosage Form : Oral Solution

Dosage Strength : 50MG/5ML

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

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01

Nanjing Well Pharmaceutical

China

Duphat

Not Confirmed

Nanjing Well is focused on R&D, production & sales of Pharmaceutical Excipients & Synthetic Lubricating base oils.

Dosage Form : Capsule, Cream / Lotion / Ointment, Emulsion, Gel, Injectable / Parenteral, Suspension, Tablet

Grade : Parenteral, Oral, Topical

Category : Emulsifying Agents, Film Formers & Plasticizers, Parenteral, Solubilizers, Surfactant & Foaming Agents, Thickeners and Stabilizers, Topical

Brand Name : Polysorbate 80

Application : Emulsifying Agents, Film Formers & Plasticizers, Parenteral, Solubilizers, Surfactant & Foaming Agents, Thickeners and Stabilizers, Topical

Excipient Details : Polysorbate 80 is used as a plasticizer, solubilizer, emulsifier, surfactant, and suspension stabilizer. It is also used in parenteral products.

Pharmacopoeia Ref : ChP/USP/EP/JP

Technical Specs : NA

Ingredient(s) : Polysorbate 80

Excipients Web Link

India

Duphat

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US Medicaid Prescriptions

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Finished Drug Prices

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Market Place

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APIs

Trazodone HCl (20 Tons) API needed in China [ENA19382]

A company that focuses on research, development, manufacturing and sales of finished formulations & medical instruments is looking for suppliers of Trazodone HCl (20 Tons) API for commercial purposes. The suppliers must support this enquiry with USDMF & CoA.

18 Apr 2024

Triticum Vulgare Extract needed in Turkey [ENA15180]

A company that focuses on research, development & manufacturing of solid, semi-solid and liquid dosage forms is looking for suppliers of Triticum Vulgare Extract. The required quantity is 100 g for trial & later 1 MT for commercial purpose. The suppliers must support this enquiry with DMF & GMP.

30 Sep 2022

Trazodone API needed in India [ENA13237]

A leading pharmaceutical company that specializes in the development, manufacturing & marketing of various finished formulations is looking for suppliers of Trazodone API. The suppliers must support this enquiry with CoA.

07 Apr 2022

USP/ BP Grade Trazodone Hydrochloride API needed in Brazil [ENA13043]

A large pharmaceutical manufacturing company that deals in portfolios like dermatological, cardiological, gynaecological, gastric, oncology, respiratory & CNS is looking for suppliers of USP/ BP Grade Trazodone Hydrochloride API for development purpose. The suppliers must support this enquiry with CoA.

21 Mar 2022

Trazodone HCl API needed in the United States [ENA12510]

A drug formulation & development company that produces finished products is looking for suppliers of Trazodone HCl API for commercial purpose. The initially required quantity is 10 MT & later 60 MT/ annum. The suppliers must support this enquiry with USDMF.

25 Jan 2022

Various APIs needed in Vietnam [ENA09884]

One of the fastest growing organizations in the pharmaceutical industry is looking for suppliers of Various APIs for commercial manufacturing purposes. The suppliers must support this enquiry with GMP and DMF. 1. Apixaban (3 kg) API 2. Bupropion (25 kg) API 3. Canagliflozin (50 kg) API 4. Cyclobenzaprine HCl (10 kg) API 5. Eltrombopag Olamine (10 kg) API 6. Empagliflozin (10 kg) API 7. Lenalidomid (5 kg) API 8. Posaconazole (5 kg) API 9. Prasugrel (5 kg) API 10. Trazodone (20 kg) API

06 Mar 2021

Ph. Eur Grade Magnesium Glycerophosphate & Pharma Grade Trazodone HCl APIs needed in Lithuania [ENA09842]

An international pharmaceutical company that deals in developing and manufacturing food supplements, medical devices and herbal products is looking for suppliers of Ph. Eur Grade Magnesium Glycerophosphate & Pharma Grade Trazodone Hydrochloride APIs for development and then commercial purposes. The required quantity is MOQ for each. The suppliers must support this enquiry with DMF.

02 Mar 2021

Various APIs needed in France [ENA09760]

A large pharmaceutical company that deals in the R&D and production of various dosage forms such as OSDs, semi-solids, non-sterile liquids & sterile liquids is looking for suppliers of Various APIs for commercial purposes. The suppliers must support this enquiry with GMP, CEP and WC. 1. Micronized Tolterodine Hydrogen Tartrate (4 kg/ annum) API 2. Chlorprothixene Hydrochloride (180 kg/ annum) API 3. Phenobarbital (2.5 MT /annum) API 4. Trazodone HCl (540 kg/ annum) API 5. Doxazosin Mesylate (4 kg/ annum) API 6. Amlodipine Besylate (60 kg/ annum) API 7. Telmisartan (460 kg/ annum) API

18 Feb 2021

Trazodone Hydrochloride API needed in the United States [ENA02824]

A U.S. based pharmaceutical company that specializes in the development, manufacturing, and distribution of niche generic products is looking for suppliers of Trazodone Hydrochloride API with USDMF.

04 Dec 2018

Enquiry// USP grade Trazodone Hydrochloride working standard 5 g needed in India [ENA00448]

A distribution company in India is searching for suppliers of USP grade Trazodone Hydrochloride working standard 5 g for one of their clients.

09 Aug 2017

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FDF DOSSIERS

Various Finished Dosage Formulations needed in Romania [ENA10555]

A large pharmaceutical company that devotes itself to R&D, production and marketing & sales of active pharmaceutical ingredients and pharmaceutical intermediates is looking for suppliers of Various Finished Dosage Formulations for commercial purposes. The suppliers must support this enquiry this eCTD Dossier with B.E study. The final market is Romania/ Poland. 1. Trazodone (75 mg, 150 mg) XR Tablets 2. Sulodexide (25 mg) Capsules 3. Zofenopril Calcium (7.5 mg, 30 mg) Tablets

02 Jun 2021

Trazodone Hydrochloride (300 mg) & Acamprosate Calcium (333 mg) Tablets needed in Jordan [ENA08099]

MZDS, a distributor company based in Jordan is looking for suppliers of Trazodone Hydrochloride (300 mg) & Acamprosate Calcium (333 mg) Tablets. The required quantity is 3000 units & 5,000 units respectively. Interested suppliers can contact them via their email: zriqat@hotmail.com.

30 Jul 2020

Pregabalin and Sertraline finished formulations (Supply + CTD dossier) needed in the UAE [ENA04860]

A pharmaceutical distribution company based in the UAE supplying a neuroscience specialized range of Medical and pharmaceutical products in the healthcare field is looking for suppliers of Pregabalin and Sertraline finished formulations (Supply + CTD dossier). The dosage strength and volume forecast is mentioned below. The supplier must support this enquiry with CTD dossier. 1. Pregabalin capsule 150mg- Quantity 400,000 units 2. Pregabalin capsule 300mg- Quantity 350,000 units 3. Sertraline tablet 50mg- Quantity 400,000 units 4. Trazodone tablet 50mg- Quantity 340,000 units

08 Aug 2019

Trazodone FDF needed in UAE [ENA03922]

Dubai based Pharmaceutical company is looking for Trazodone FDF. Interested suppliers must support with EU-GMP certificate.

15 Apr 2019

EU CTD dossiers of Trazodone and Naftidrofuryl formulations needed in the Czech Republic [ENA03550]

A family company active in the market for innovative products is looking for suppliers of the following products for Czech and Slovakia: 1. Trazodone controlled-release tablets 150 mg 2. Naftidrofuryl 100 mg capsules

28 Feb 2019

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Patents & EXCLUSIVITIES

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US Patents

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REF. STANDARDS & IMPURITIES

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ABOUT THIS PAGE

Trazodone Hydrochloride Manufacturers

A Trazodone Hydrochloride manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Trazodone Hydrochloride, including repackagers and relabelers. The FDA regulates Trazodone Hydrochloride manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Trazodone Hydrochloride API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Trazodone Hydrochloride manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Trazodone Hydrochloride Suppliers

A Trazodone Hydrochloride supplier is an individual or a company that provides Trazodone Hydrochloride active pharmaceutical ingredient (API) or Trazodone Hydrochloride finished formulations upon request. The Trazodone Hydrochloride suppliers may include Trazodone Hydrochloride API manufacturers, exporters, distributors and traders.

click here to find a list of Trazodone Hydrochloride suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Trazodone Hydrochloride USDMF

A Trazodone Hydrochloride DMF (Drug Master File) is a document detailing the whole manufacturing process of Trazodone Hydrochloride active pharmaceutical ingredient (API) in detail. Different forms of Trazodone Hydrochloride DMFs exist exist since differing nations have different regulations, such as Trazodone Hydrochloride USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Trazodone Hydrochloride DMF submitted to regulatory agencies in the US is known as a USDMF. Trazodone Hydrochloride USDMF includes data on Trazodone Hydrochloride's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Trazodone Hydrochloride USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Trazodone Hydrochloride suppliers with USDMF on PharmaCompass.

Trazodone Hydrochloride JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Trazodone Hydrochloride Drug Master File in Japan (Trazodone Hydrochloride JDMF) empowers Trazodone Hydrochloride API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Trazodone Hydrochloride JDMF during the approval evaluation for pharmaceutical products. At the time of Trazodone Hydrochloride JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Trazodone Hydrochloride suppliers with JDMF on PharmaCompass.

Trazodone Hydrochloride KDMF

In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

Pharmaceutical companies submit a Trazodone Hydrochloride Drug Master File in Korea (Trazodone Hydrochloride KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Trazodone Hydrochloride. The MFDS reviews the Trazodone Hydrochloride KDMF as part of the drug registration process and uses the information provided in the Trazodone Hydrochloride KDMF to evaluate the safety and efficacy of the drug.

After submitting a Trazodone Hydrochloride KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Trazodone Hydrochloride API can apply through the Korea Drug Master File (KDMF).

click here to find a list of Trazodone Hydrochloride suppliers with KDMF on PharmaCompass.

Trazodone Hydrochloride CEP

A Trazodone Hydrochloride CEP of the European Pharmacopoeia monograph is often referred to as a Trazodone Hydrochloride Certificate of Suitability (COS). The purpose of a Trazodone Hydrochloride CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Trazodone Hydrochloride EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Trazodone Hydrochloride to their clients by showing that a Trazodone Hydrochloride CEP has been issued for it. The manufacturer submits a Trazodone Hydrochloride CEP (COS) as part of the market authorization procedure, and it takes on the role of a Trazodone Hydrochloride CEP holder for the record. Additionally, the data presented in the Trazodone Hydrochloride CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Trazodone Hydrochloride DMF.

A Trazodone Hydrochloride CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Trazodone Hydrochloride CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Trazodone Hydrochloride suppliers with CEP (COS) on PharmaCompass.

Trazodone Hydrochloride WC

A Trazodone Hydrochloride written confirmation (Trazodone Hydrochloride WC) is an official document issued by a regulatory agency to a Trazodone Hydrochloride manufacturer, verifying that the manufacturing facility of a Trazodone Hydrochloride active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Trazodone Hydrochloride APIs or Trazodone Hydrochloride finished pharmaceutical products to another nation, regulatory agencies frequently require a Trazodone Hydrochloride WC (written confirmation) as part of the regulatory process.

click here to find a list of Trazodone Hydrochloride suppliers with Written Confirmation (WC) on PharmaCompass.

Trazodone Hydrochloride NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Trazodone Hydrochloride as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Trazodone Hydrochloride API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Trazodone Hydrochloride as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Trazodone Hydrochloride and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Trazodone Hydrochloride NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Trazodone Hydrochloride suppliers with NDC on PharmaCompass.

Trazodone Hydrochloride GMP

Trazodone Hydrochloride Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Trazodone Hydrochloride GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Trazodone Hydrochloride GMP manufacturer or Trazodone Hydrochloride GMP API supplier for your needs.

Trazodone Hydrochloride CoA

A Trazodone Hydrochloride CoA (Certificate of Analysis) is a formal document that attests to Trazodone Hydrochloride's compliance with Trazodone Hydrochloride specifications and serves as a tool for batch-level quality control.

Trazodone Hydrochloride CoA mostly includes findings from lab analyses of a specific batch. For each Trazodone Hydrochloride CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Trazodone Hydrochloride may be tested according to a variety of international standards, such as European Pharmacopoeia (Trazodone Hydrochloride EP), Trazodone Hydrochloride JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Trazodone Hydrochloride USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.

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44 API Suppliers

20 USDMF

9 CEP/COS

2 JDMF

4 EU WC

2 KDMF

18 NDC API

28 Listed Suppliers

$ API Reference Price

DEVELOPMENTS

3 Drugs in Development

INTERMEDIATES

25 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

165 FDF Dossiers

68 FDA Orange Book

31 Europe

24 Canada

12 South Africa

30 Listed Dossiers

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46 Coating Systems & Additives

33 Direct Compression

28 Controlled & Modified Release

22 Granulation

21 Solubilizers

21 Thickeners and Stabilizers

20 Disintegrants & Superdisintegrants

16 Co-Processed Excipients

14 Lubricants & Glidants

11 Topical

10 Parenteral

10 Film Formers & Plasticizers

9 Taste Masking

7 Emulsifying Agents

6 Chewable & Orodispersible Aids

5 Empty Capsules