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Chemistry

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Also known as: 865759-25-7, Syr-472, Trelagliptin(syr-472), Trelagliptin [usan], Q836owg55h, Chembl1650443
Molecular Formula
C18H20FN5O2
Molecular Weight
357.4  g/mol
InChI Key
IWYJYHUNXVAVAA-OAHLLOKOSA-N
FDA UNII
Q836OWG55H

Trelagliptin
Trelagliptin is under investigation in clinical trial NCT03555591 (Specified Drug-Use Survey of Trelagliptin Tablets "Survey on Long-term Use in Patients With Type 2 Diabetes Mellitus").
1 2D Structure

Trelagliptin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-[[6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxopyrimidin-1-yl]methyl]-4-fluorobenzonitrile
2.1.2 InChI
InChI=1S/C18H20FN5O2/c1-22-17(25)8-16(23-6-2-3-15(21)11-23)24(18(22)26)10-13-7-14(19)5-4-12(13)9-20/h4-5,7-8,15H,2-3,6,10-11,21H2,1H3/t15-/m1/s1
2.1.3 InChI Key
IWYJYHUNXVAVAA-OAHLLOKOSA-N
2.1.4 Canonical SMILES
CN1C(=O)C=C(N(C1=O)CC2=C(C=CC(=C2)F)C#N)N3CCCC(C3)N
2.1.5 Isomeric SMILES
CN1C(=O)C=C(N(C1=O)CC2=C(C=CC(=C2)F)C#N)N3CCC[C@H](C3)N
2.2 Other Identifiers
2.2.1 UNII
Q836OWG55H
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Syr-472

2. Trelagliptin Succinate

2.3.2 Depositor-Supplied Synonyms

1. 865759-25-7

2. Syr-472

3. Trelagliptin(syr-472)

4. Trelagliptin [usan]

5. Q836owg55h

6. Chembl1650443

7. 865759-25-7 (free Base)

8. (r)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)methyl)-4-fluorobenzonitrile

9. Trelagliptin (usan)

10. (r)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)methyl)-4-fluorobenzonitrile.

11. 2-[[6-[(3r)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxopyrimidin-1-yl]methyl]-4-fluorobenzonitrile

12. Trelagliptin [usan:inn]

13. Unii-q836owg55h

14. Trelagliptin(syr472)

15. Trelagliptin [mi]

16. Trelagliptin [inn]

17. Schembl175726

18. Trelagliptin [who-dd]

19. Dtxsid00235678

20. Ex-a470

21. Chebi:134715

22. Bdbm50335784

23. Mfcd22572746

24. Nsc802901

25. S7513

26. Zinc34505198

27. Akos026674097

28. Ccg-268122

29. Cs-1041

30. Db15323

31. Nsc-802901

32. Ncgc00378845-01

33. Ac-30279

34. As-75009

35. Hy-15408

36. A3889

37. D10178

38. A855303

39. Q27287099

40. 2-((6-((3r)-3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2h)- Yl)methyl)-4-fluorobenzonitrile

41. 2-((6-((3r)-3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)methyl)-4-fluorobenzonitrile

42. 2-({6-[(3r)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl}methyl)-4-fluorobenzonitrile

43. 2-[[6-[(3~{r})-3-azanylpiperidin-1-yl]-3-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]methyl]-4-fluoranyl-benzenecarboni

44. 2-[[6-[(3~{r})-3-azanylpiperidin-1-yl]-3-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]methyl]-4-fluoranyl-benzenecarbonitrile

45. 2-[6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2h-pyrimidin-1-ylmethyl]-4-fluorobenzonitrile

46. 6rl

47. Benzonitrile, 2-((6-((3r)-3-amino-1-piperidinyl)-3,4-dihydro-3-methyl-2,4-dioxo-1(2h)- Pyrimidinyl)methyl)-4-fluoro-

48. Benzonitrile, 2-((6-((3r)-3-amino-1-piperidinyl)-3,4-dihydro-3-methyl-2,4-dioxo-1(2h)-pyrimidinyl)methyl)-4-fluoro-

2.4 Create Date
2007-03-27
3 Chemical and Physical Properties
Molecular Weight 357.4 g/mol
Molecular Formula C18H20FN5O2
XLogP30.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Exact Mass357.16010306 g/mol
Monoisotopic Mass357.16010306 g/mol
Topological Polar Surface Area93.7 Ų
Heavy Atom Count26
Formal Charge0
Complexity657
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

API Reference Price

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15-Dec-2021
16-Oct-2024
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ABOUT THIS PAGE

Trelagliptin Manufacturers

A Trelagliptin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Trelagliptin, including repackagers and relabelers. The FDA regulates Trelagliptin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Trelagliptin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Trelagliptin manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Trelagliptin Suppliers

A Trelagliptin supplier is an individual or a company that provides Trelagliptin active pharmaceutical ingredient (API) or Trelagliptin finished formulations upon request. The Trelagliptin suppliers may include Trelagliptin API manufacturers, exporters, distributors and traders.

click here to find a list of Trelagliptin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Trelagliptin GMP

Trelagliptin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Trelagliptin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Trelagliptin GMP manufacturer or Trelagliptin GMP API supplier for your needs.

Trelagliptin CoA

A Trelagliptin CoA (Certificate of Analysis) is a formal document that attests to Trelagliptin's compliance with Trelagliptin specifications and serves as a tool for batch-level quality control.

Trelagliptin CoA mostly includes findings from lab analyses of a specific batch. For each Trelagliptin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Trelagliptin may be tested according to a variety of international standards, such as European Pharmacopoeia (Trelagliptin EP), Trelagliptin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Trelagliptin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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