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Chemistry

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Also known as: Triethylenetetramine dihydrochloride, 38260-01-4, Syprine, Trientine dihydrochloride, Trientine hcl, Mk-0681
Molecular Formula
C6H20Cl2N4
Molecular Weight
219.15  g/mol
InChI Key
WYHIICXRPHEJKI-UHFFFAOYSA-N
FDA UNII
HC3NX54582

Trientine Hydrochloride
An ethylenediamine derivative used as stabilizer for EPOXY RESINS, as ampholyte for ISOELECTRIC FOCUSING and as chelating agent for copper in HEPATOLENTICULAR DEGENERATION.
1 2D Structure

Trientine Hydrochloride

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
N'-[2-(2-aminoethylamino)ethyl]ethane-1,2-diamine;dihydrochloride
2.1.2 InChI
InChI=1S/C6H18N4.2ClH/c7-1-3-9-5-6-10-4-2-8;;/h9-10H,1-8H2;2*1H
2.1.3 InChI Key
WYHIICXRPHEJKI-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C(CNCCNCCN)N.Cl.Cl
2.2 Other Identifiers
2.2.1 UNII
HC3NX54582
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Syprine

2. Trien

3. Trientine

4. Trientine Dihydrochloride

5. Triethylenetetramine

2.3.2 Depositor-Supplied Synonyms

1. Triethylenetetramine Dihydrochloride

2. 38260-01-4

3. Syprine

4. Trientine Dihydrochloride

5. Trientine Hcl

6. Mk-0681

7. 1,2-ethanediamine, N,n'-bis(2-aminoethyl)-, Dihydrochloride

8. Triethylene Tetramine Dihydrochloride

9. Teta

10. N,n'-bis(2-aminoethyl)-1,2-ethanediamine Dihydrochloride

11. Hc3nx54582

12. Nsc-759164

13. N1,n1'-(ethane-1,2-diyl)bis(ethane-1,2-diamine) Dihydrochloride

14. Trien Dihydrochloride

15. Cuprid

16. 1,2-ethanediamine,n1,n2-bis(2-aminoethyl)-, Hydrochloride (1:2)

17. Trientine Hydrochloride [usan]

18. Einecs 253-854-3

19. Mk 0681

20. N,n'-bis(2-aminoethyl)ethylenediamine Dihydrochloride

21. Laszarin

22. Metalite

23. Unii-hc3nx54582

24. Trientine-2hcl

25. 2,2'-ethylenediiminobis(ethylamine) Dihydrochloride

26. Syprine (tn)

27. Trientine Hydrochloride [usan:usp]

28. Trientinedihydrochloride

29. Triethyl Enetetramine 2hcl

30. Schembl506189

31. Chebi:9706

32. Chembl3989777

33. Dtxsid2057863

34. Amy3335

35. Tja-250

36. Mk-681

37. N'-[2-(2-aminoethylamino)ethyl]ethane-1,2-diamine;dihydrochloride

38. S6585

39. Trientine Hydrochloride (jp17/usp)

40. Trientine Hydrochloride [jan]

41. Trientine Dihydrochloride [mi]

42. Akos028109579

43. Ccg-213505

44. Nsc 759164

45. Trientine Hydrochloride [vandf]

46. Trientine Hydrochloride [usp-rs]

47. Trientine Dihydrochloride [mart.]

48. Bs-49370

49. Trientine Dihydrochloride [who-dd]

50. Db-049259

51. Ft-0639448

52. Trientine Hydrochloride [orange Book]

53. D00736

54. E78246

55. Trientine Hydrochloride [usp Monograph]

56. 260t014

57. Q27279855

58. N1,n1'-(ethane-1,2-diyl)diethane-1,2-diamine Dihydrochloride

59. N\'-[2-(2-aminoethylamino)ethyl]ethane-1,2-diamine,dihydrochloride

60. Trientine Hydrochloride, United States Pharmacopeia (usp) Reference Standard

61. Triethylenetetramine Dihydrochloride, Puriss., 2xcryst., >=99.0% (at)

62. Trientine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 219.15 g/mol
Molecular Formula C6H20Cl2N4
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count4
Rotatable Bond Count7
Exact Mass218.1065020 g/mol
Monoisotopic Mass218.1065020 g/mol
Topological Polar Surface Area76.1 Ų
Heavy Atom Count12
Formal Charge0
Complexity49.7
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Drug and Medication Information
4.1 Drug Information
1 of 2  
Drug NameSyprine
PubMed HealthTrientine (By mouth)
Drug ClassesHeavy Metal Chelator
Drug LabelTrientine hydrochloride is N,N'-bis (2-aminoethyl)-1,2-ethanediamine dihydrochloride. It is a white to pale yellow crystalline hygroscopic powder. It is freely soluble in water, soluble in methanol, slightly soluble in ethanol, and insoluble in chlor
Active IngredientTrientine hydrochloride
Dosage FormCapsule
RouteOral
Strength250mg
Market StatusPrescription
CompanyAton

2 of 2  
Drug NameSyprine
PubMed HealthTrientine (By mouth)
Drug ClassesHeavy Metal Chelator
Drug LabelTrientine hydrochloride is N,N'-bis (2-aminoethyl)-1,2-ethanediamine dihydrochloride. It is a white to pale yellow crystalline hygroscopic powder. It is freely soluble in water, soluble in methanol, slightly soluble in ethanol, and insoluble in chlor
Active IngredientTrientine hydrochloride
Dosage FormCapsule
RouteOral
Strength250mg
Market StatusPrescription
CompanyAton

4.2 Drug Indication

Cufence is indicated for the treatment of Wilsons disease in patients intolerant to D-Penicillamine therapy, in adults and children aged 5 years or older.


5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Chelating Agents

Chemicals that bind to and remove ions from solutions. Many chelating agents function through the formation of COORDINATION COMPLEXES with METALS. (See all compounds classified as Chelating Agents.)


5.2 FDA Pharmacological Classification
5.2.1 Pharmacological Classes
Metal Chelator [EPC]; Metal Chelating Activity [MoA]
5.3 ATC Code

A16A


API SUPPLIERS

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Nuray Chemicals Private Limited

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ChemWerth Inc

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Biophore India Pharmaceuticals Pvt...

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HRV Global Life Sciences

India

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BrightGene Bio-Medical Technology ...

China

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Emcure Pharmaceuticals

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Apothecon Pharmaceuticals

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MSN Laboratories

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Suven Life Sciences Limited

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LTD","supplierCountry":"INDIA","foreign_port":"TAIPEI","customer":"M\/S","customerCountry":"TAIWAN","quantity":"56.00","actualQuantity":"56","unit":"KGS","unitRateFc":"2000","totalValueFC":"111479.4","currency":"USD","unitRateINR":150196.42857142858,"date":"12-Apr-2022","totalValueINR":"8411000","totalValueInUsd":"111479.4","indian_port":"HYDERABAD AIR","hs_no":"29212990","bill_no":"9640606","productDescription":"API","marketType":"REGULATED MARKET","country":"TAIWAN","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"425\/3RT, D.NO.7-1-621\/328,,SANJEEV AREDDY NAGAR,, HYDERABAD,TELANGANA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1667500200,"product":"PHARMACEUTICAL PRODUCT-TRIENTINE TETRAHY","address":"25, 12TH CROSS STREET, SHASTRI NAGAR,","city":"CHENNAI\/TAMILNADU","supplier":"NURAY CHEMICALS PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"NEW YORK","customer":"THE PURCHASE MANAGER..","customerCountry":"UNITED STATES","quantity":"84.76","actualQuantity":"84.76","unit":"KGS","unitRateFc":"1400","totalValueFC":"118658.1","currency":"USD","unitRateINR":114252.00566304861,"date":"04-Nov-2022","totalValueINR":"9684000","totalValueInUsd":"118658.1","indian_port":"MADRAS AIR","hs_no":"29212990","bill_no":"5255147","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"MADRAS AIR","supplierAddress":"25, 12TH CROSS STREET, SHASTRI NAGAR,, CHENNAI\/TAMILNADU","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1673289000,"product":"TRIENTINE HYDROCHLORIDE BATCH NO- HT0021","address":"MSN HOUSE, PLOT NO.C-24,,INDUSTRIA L ESTATE, SANATHNAGAR","city":"HYDERABAD,TELANGANA","supplier":"MSN ORGANICS PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"BOGOTA","customer":"HB HUMAN BIOSCIENCE ","customerCountry":"COLOMBIA","quantity":"7.00","actualQuantity":"7","unit":"KGS","unitRateFc":"4000","totalValueFC":"28070.1","currency":"USD","unitRateINR":327857.14285714284,"date":"10-Jan-2023","totalValueINR":"2295000","totalValueInUsd":"28070.1","indian_port":"HYDERABAD AIR","hs_no":"29212990","bill_no":"6853695","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"COLOMBIA","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"MSN HOUSE, PLOT NO.C-24,,INDUSTRIA L ESTATE, SANATHNAGAR, HYDERABAD,TELANGANA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1675362600,"product":"TRIENTINE HYDROCHLORIDE USP","address":"FIRST FLOOR SFNO.534\/4A2B NO 102 SAMY APARTMENT","city":"CHENNAI","supplier":"STHREE CHEMICALS PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"ISTANBUL","customer":"THE PURCHASE MANAGER","customerCountry":"TURKEY","quantity":"30.00","actualQuantity":"30","unit":"KGS","unitRateFc":"2000","totalValueFC":"46446.3","currency":"USD","unitRateINR":127866.66666666667,"date":"03-Feb-2023","totalValueINR":"3836000","totalValueInUsd":"46446.3","indian_port":"MADRAS AIR","hs_no":"29212990","bill_no":"7516935","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"TURKEY","selfForZScoreResived":"Pharma Grade","supplierPort":"MADRAS AIR","supplierAddress":"FIRST FLOOR SFNO.534\/4A2B NO 102 SAMY APARTMENT, CHENNAI","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1692210600,"product":"TRIENTINE HCL","address":"PLOT NO. 193 HOUSE NO. 5-35\/50 PRASHANT NAGAR KUKATPALLY  AP","city":"Hyderabad","supplier":"BIOPHORE INDIA PHARMACEUTICALS PVT LTD","supplierCountry":"INDIA","foreign_port":"NA","customer":"TO THE ORDER OF","customerCountry":"HONG KONG","quantity":"7.00","actualQuantity":"7","unit":"KGS","unitRateFc":"3110.1","totalValueFC":"21524.4","currency":"USD","unitRateINR":254714.28842857145,"date":"17-Aug-2023","totalValueINR":"1783000.019","totalValueInUsd":"21524.4","indian_port":"HYDERABAD ICD","hs_no":"29212990","bill_no":"0","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"HONG KONG","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD ICD","supplierAddress":"PLOT NO. 193 HOUSE NO. 5-35\/50 PRASHANT NAGAR KUKATPALLY  AP, Hyderabad","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1698604200,"product":"TRIENTINE HYDROCHLORIDE USP (RE-EXPORT)(RE-IMPORTED VIDE BE NO. 7680425 DT.05.09.2023 UNDER NOTF 158\/95 SR NO.2)","address":"425\/3RT, D.NO.7-1-621\/328, SANJEEVAREDDY NAGAR,","city":"HYDERABAD, AP.","supplier":"AZICO BIOPHORE INDIA PVT. LTD","supplierCountry":"INDIA","foreign_port":"TAIPEI","customer":"TO THE ORDER","customerCountry":"TAIWAN","quantity":"42.70","actualQuantity":"42.7","unit":"KGS","unitRateFc":"2000","totalValueFC":"84597.6","currency":"USD","unitRateINR":164894.61358313815,"date":"30-Oct-2023","totalValueINR":"7041000","totalValueInUsd":"84597.6","indian_port":"Hyderabad Air","hs_no":"29212990","bill_no":"4999836","productDescription":"Re-export","marketType":"REGULATED MARKET","country":"TAIWAN","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"425\/3RT, D.NO.7-1-621\/328, SANJEEVAREDDY NAGAR,, HYDERABAD, AP.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1704393000,"product":"TRIENTINE HYDROCHLORIDE USP","address":"425\/3RT, D.NO.7-1-621\/328, SANJEEVAREDDY NAGAR,","city":"HYDERABAD, AP.","supplier":"AZICO BIOPHORE INDIA PVT. LTD","supplierCountry":"INDIA","foreign_port":"BOGOTA","customer":"LIMINAL THERAPEUTICS SAS","customerCountry":"COLOMBIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"1500","totalValueFC":"1489","currency":"USD","unitRateINR":123750,"date":"05-Jan-2024","totalValueINR":"123750","totalValueInUsd":"1489","indian_port":"Hyderabad Air","hs_no":"29212990","bill_no":"6531561","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"COLOMBIA","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"425\/3RT, D.NO.7-1-621\/328, SANJEEVAREDDY NAGAR,, HYDERABAD, AP.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1709749800,"product":"PHARMACEUTICAL RAW MATERIAL TRIENTINE HYDROCHLORIDE USP BATCH NO.:1TRN323001 MFGDT. 17 FEB 23 RETEST 16 FEB 2026","address":"T-184, MIDC, BHOSARI,","city":"PUNE-MAHARASHTRA","supplier":"EMCURE PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"ISTANBUL","customer":"MERKO PHARMACEUTICAL & CHEMICAL MAT","customerCountry":"TURKEY","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"2700","totalValueFC":"12968.1","currency":"USD","unitRateINR":215364,"date":"07-Mar-2024","totalValueINR":"1076820","totalValueInUsd":"12968.1","indian_port":"Bombay Air","hs_no":"29212990","bill_no":"8146985","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"TURKEY","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"T-184, MIDC, BHOSARI,, PUNE-MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1724869800,"product":"TRIENTINE HYDROCHLORIDE USP BATCH NO. S133A24004 MFG DT. 31.07.2024 EXP DT. 30.06.2029 AS PER INVOICE","address":"NIKITA BAUNGLOW, NEAR PRAGATI","city":"GUJARAT","supplier":"APOTHECON PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"TAIPEI","customer":"SUNNY PHARMTECH INC.","customerCountry":"TAIWAN","quantity":"30.00","actualQuantity":"30","unit":"KGS","unitRateFc":"2700","totalValueFC":"77560.4","currency":"USD","unitRateINR":216854.99000000002,"date":"29-Aug-2024","totalValueINR":"6505649.7","totalValueInUsd":"77560.4","indian_port":"Ahmedabad Air","hs_no":"29212990","bill_no":"3591138","productDescription":"API","marketType":"REGULATED MARKET","country":"TAIWAN","selfForZScoreResived":"Pharma Grade","supplierPort":"Ahmedabad Air","supplierAddress":"NIKITA BAUNGLOW, NEAR PRAGATI, GUJARAT","customerAddress":""},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1658341800,"product":"TRIENTINE HYDROCHLORIDE (QTY:2X200 MG,VALUE: USD 257\/EACH)(FOC)","address":"P.NO. D6 & D8, SY.NO. 234\/2,234\/3, ,235\/2 & 542\/2, IKP KNOWLEDGE PARK,","city":"TURKAPALLY-V SHAMIRPET HYDERABAD,TE","supplier":"USP","supplierCountry":"INDIA","foreign_port":"NA","customer":"UNITED STATES PHARMACOPEIA - INDIA PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.0004","unit":"KGS","unitRateFc":"1285000","totalValueFC":"531.3","currency":"USD","unitRateINR":"105612775","date":"21-Jul-2022","totalValueINR":"42245.11","totalValueInUsd":"531.3","indian_port":"HYDERABAD AIR","hs_no":"29212990","bill_no":"9647527","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"P.NO. D6 & D8, SY.NO. 234\/2,234\/3, ,235\/2 & 542\/2, IKP KNOWLEDGE PARK,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1693852200,"product":"TRIENTINE HYDROCHLORIDE. USP (RE-IMPORT) (EXPORTED VIDE SB NO.9031686 DT.03.04.2023)","address":"425\/3RT, D.NO.7-1-621\/328,","city":"HYDERABAD, AP.","supplier":"BIOPHORE INDIA PHARMACEUTICALS PVT LTD","supplierCountry":"INDIA","foreign_port":"TAIPEI","customer":"AZICO BIOPHORE INDIA PVT. LTD","customerCountry":"INDIA","quantity":"44.53","actualQuantity":"44.534","unit":"KGS","unitRateFc":"2000","totalValueFC":"90024.9","currency":"USD","unitRateINR":"167800","date":"05-Sep-2023","totalValueINR":"7472805.2","totalValueInUsd":"90024.9","indian_port":"Hyderabad Air","hs_no":"29212990","bill_no":"7680425","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"TAIPEI","supplierAddress":"1 DEERPARK DRIVE, SUITE F-8,MONMOUTH JUNCTION, NJ 08852UNITED STATES UNITED STATES","customerAddress":"425\/3RT, D.NO.7-1-621\/328,"}]
20-Jan-2021
29-Aug-2024
KGS
overview
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country Total Quantity
(KGS)
Average Price
(USD/KGS)
Number of Transactions

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FDF Dossiers

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01

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothBiophore is a research-driven global pharmaceutical company focused on niche APIs for the generic industry.

Flag India
Digital Content Digital Content

Regulatory Info :

Registration Country : India

Trientine Dihydrochloride

Brand Name :

Dosage Form : Capsule

Dosage Strength : 250MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Biophore

02

arrow
CPHI Middle east
Not Confirmed
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothDRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

Flag India
Digital Content Digital Content

Regulatory Info : RX

Registration Country : USA

TRIENTINE HYDROCHLORIDE

Brand Name : TRIENTINE HYDROCHLORIDE

Dosage Form : CAPSULE;ORAL

Dosage Strength : 250MG

Packaging :

Approval Date : 2019-07-03

Application Number : 211076

Regulatory Info : RX

Registration Country : USA

Dr Reddy Company Banner

03

CPHI Middle east
Not Confirmed
arrow
arrow
CPHI Middle east
Not Confirmed

TRIENTINE HYDROCHLORIDE

Brand Name : TRIENTINE HYDROCHLORIDE

Dosage Form : CAPSULE;ORAL

Dosage Strength : 250MG

Packaging :

Approval Date : 2019-09-16

Application Number : 209415

Regulatory Info : DISCN

Registration Country : USA

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04

Clinect

Australia
CPHI Middle east
Not Confirmed
arrow

Clinect

Australia
arrow
CPHI Middle east
Not Confirmed

trientine

Brand Name : Trientine Waymade

Dosage Form :

Dosage Strength :

Packaging : 100

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Australia

blank

05

CPHI Middle east
Not Confirmed
arrow
arrow
CPHI Middle east
Not Confirmed

Trientine Dihydrochloride

Brand Name :

Dosage Form : Hard Capsule

Dosage Strength : 250MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

blank

06

CPHI Middle east
Not Confirmed
arrow
arrow
CPHI Middle east
Not Confirmed

TRIENTINE HYDROCHLORIDE

Brand Name : TRIENTINE HYDROCHLORIDE

Dosage Form : CAPSULE;ORAL

Dosage Strength : 250MG

Packaging :

Approval Date : 2019-05-22

Application Number : 211134

Regulatory Info : RX

Registration Country : USA

blank

07

CPHI Middle east
Not Confirmed
arrow
arrow
CPHI Middle east
Not Confirmed

TRIENTINE HYDROCHLORIDE

Brand Name : TRIENTINE HYDROCHLORIDE

Dosage Form : CAPSULE;ORAL

Dosage Strength : 500MG

Packaging :

Approval Date : 2023-09-22

Application Number : 212238

Regulatory Info : RX

Registration Country : USA

blank

08

CPHI Middle east
Not Confirmed
arrow
arrow
CPHI Middle east
Not Confirmed

Trientine Hydrochloride

Brand Name :

Dosage Form : Tablets

Dosage Strength : 250mg

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

blank

09

Waymade

United Kingdom
CPHI Middle east
Not Confirmed
arrow

Waymade

United Kingdom
arrow
CPHI Middle east
Not Confirmed

Trientina

Brand Name : TRIENTINA WAYMADE

Dosage Form : Hard Capsules

Dosage Strength : 200 mg

Packaging : 100 UNITS 200 MG - ORAL USE

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

blank

10

CPHI Middle east
Not Confirmed
arrow
arrow
CPHI Middle east
Not Confirmed

TRIENTINE HYDROCHLORIDE

Brand Name : TRIENTINE HYDROCHLORIDE

Dosage Form : CAPSULE;ORAL

Dosage Strength : 250MG

Packaging :

Approval Date : 2019-04-26

Application Number : 211554

Regulatory Info : RX

Registration Country : USA

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FDA Orange Book

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01

DR REDDYS

India
arrow
CPHI Middle east
Not Confirmed
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothDRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

Flag India
Digital Content Digital Content

RLD : No

TE Code : AB

TRIENTINE HYDROCHLORIDE

Brand Name : TRIENTINE HYDROCHLORIDE

Dosage Form : CAPSULE;ORAL

Dosage Strength : 250MG

Approval Date : 2019-07-03

Application Number : 211076

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

Dr Reddy Company Banner

02

CPHI Middle east
Not Confirmed
arrow
arrow
CPHI Middle east
Not Confirmed

TRIENTINE HYDROCHLORIDE

Brand Name : TRIENTINE HYDROCHLORIDE

Dosage Form : CAPSULE;ORAL

Dosage Strength : 250MG

Approval Date : 2018-02-07

Application Number : 207567

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

blank

03

AMNEAL

U.S.A
CPHI Middle east
Not Confirmed
arrow

AMNEAL

U.S.A
arrow
CPHI Middle east
Not Confirmed

TRIENTINE HYDROCHLORIDE

Brand Name : TRIENTINE HYDROCHLORIDE

Dosage Form : CAPSULE;ORAL

Dosage Strength : 250MG

Approval Date : 2019-02-08

Application Number : 210619

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

blank

04

BAUSCH

Canada
CPHI Middle east
Not Confirmed
arrow

BAUSCH

Canada
arrow
CPHI Middle east
Not Confirmed

TRIENTINE HYDROCHLORIDE

Brand Name : SYPRINE

Dosage Form : CAPSULE;ORAL

Dosage Strength : 250MG

Approval Date : 1985-11-08

Application Number : 19194

RX/OTC/DISCN : RX

RLD : Yes

TE Code : AB

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05

LUPIN LTD

India
CPHI Middle east
Not Confirmed
arrow

LUPIN LTD

India
arrow
CPHI Middle east
Not Confirmed

TRIENTINE HYDROCHLORIDE

Brand Name : TRIENTINE HYDROCHLORIDE

Dosage Form : CAPSULE;ORAL

Dosage Strength : 250MG

Approval Date : 2020-05-21

Application Number : 211637

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

blank

06

MSN

India
CPHI Middle east
Not Confirmed
arrow

MSN

India
arrow
CPHI Middle east
Not Confirmed

TRIENTINE HYDROCHLORIDE

Brand Name : TRIENTINE HYDROCHLORIDE

Dosage Form : CAPSULE;ORAL

Dosage Strength : 250MG

Approval Date : 2019-05-22

Application Number : 211134

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

blank

07

NAVINTA LLC

U.S.A
CPHI Middle east
Not Confirmed
arrow

NAVINTA LLC

U.S.A
arrow
CPHI Middle east
Not Confirmed

TRIENTINE HYDROCHLORIDE

Brand Name : TRIENTINE HYDROCHLORIDE

Dosage Form : CAPSULE;ORAL

Dosage Strength : 250MG

Approval Date : 2019-01-16

Application Number : 211251

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

blank

08

RISING

U.S.A
CPHI Middle east
Not Confirmed
arrow

RISING

U.S.A
arrow
CPHI Middle east
Not Confirmed

TRIENTINE HYDROCHLORIDE

Brand Name : TRIENTINE HYDROCHLORIDE

Dosage Form : CAPSULE;ORAL

Dosage Strength : 250MG

Approval Date : 2020-02-20

Application Number : 212238

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

blank

09

RISING

U.S.A
CPHI Middle east
Not Confirmed
arrow

RISING

U.S.A
arrow
CPHI Middle east
Not Confirmed

TRIENTINE HYDROCHLORIDE

Brand Name : TRIENTINE HYDROCHLORIDE

Dosage Form : CAPSULE;ORAL

Dosage Strength : 500MG

Approval Date : 2023-09-22

Application Number : 212238

RX/OTC/DISCN : RX

RLD : No

TE Code :

blank

10

ZYDUS PHARMS

U.S.A
CPHI Middle east
Not Confirmed
arrow

ZYDUS PHARMS

U.S.A
arrow
CPHI Middle east
Not Confirmed

TRIENTINE HYDROCHLORIDE

Brand Name : TRIENTINE HYDROCHLORIDE

Dosage Form : CAPSULE;ORAL

Dosage Strength : 250MG

Approval Date : 2019-04-26

Application Number : 211554

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

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US Medicaid Prescriptions

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01

arrow
CPHI Middle east
Not Confirmed
arrow
CPHI Middle east
Not Confirmed

Company :

Trientine HCl

Drug Cost (USD) : 617,408

Year : 2022

Prescribers :

Prescriptions : 36

blank

02

arrow
CPHI Middle east
Not Confirmed
arrow
CPHI Middle east
Not Confirmed

Company :

Trientine HCl

Drug Cost (USD) : 5,587,864

Year : 2022

Prescribers : 109

Prescriptions : 877

blank

03

arrow
CPHI Middle east
Not Confirmed
arrow
CPHI Middle east
Not Confirmed

Company :

Trientine HCl

Drug Cost (USD) : 766,879

Year : 2021

Prescribers :

Prescriptions : 47

blank

04

arrow
CPHI Middle east
Not Confirmed
arrow
CPHI Middle east
Not Confirmed

Company :

Trientine HCl

Drug Cost (USD) : 5,059,788

Year : 2021

Prescribers : 98

Prescriptions : 805

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05

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CPHI Middle east
Not Confirmed
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CPHI Middle east
Not Confirmed

Company :

Trientine HCl

Drug Cost (USD) : 2,666,049

Year : 2020

Prescribers : 12

Prescriptions : 90

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06

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CPHI Middle east
Not Confirmed
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CPHI Middle east
Not Confirmed

Company :

Trientine HCl

Drug Cost (USD) : 2,956,834

Year : 2019

Prescribers : 26

Prescriptions : 113

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07

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CPHI Middle east
Not Confirmed
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CPHI Middle east
Not Confirmed

Company :

Trientine HCl

Drug Cost (USD) : 9,841,906

Year : 2019

Prescribers : 80

Prescriptions : 639

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08

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CPHI Middle east
Not Confirmed
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CPHI Middle east
Not Confirmed

Company :

Trientine HCl

Drug Cost (USD) : 7,959,440

Year : 2018

Prescribers : 74

Prescriptions : 353

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09

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CPHI Middle east
Not Confirmed
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CPHI Middle east
Not Confirmed

Company :

Trientine HCl

Drug Cost (USD) : 6,198,477

Year : 2018

Prescribers : 66

Prescriptions : 390

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10

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CPHI Middle east
Not Confirmed
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CPHI Middle east
Not Confirmed

Company :

Trientine HCl

Drug Cost (USD) : 13,236,187

Year : 2017

Prescribers : 88

Prescriptions : 658

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Finished Drug Prices

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01

Brand Name : CUFENCE

U.S.A
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CPHI Middle east
Not Confirmed

Brand Name : CUFENCE

U.S.A
arrow
CPHI Middle east
Not Confirmed

Trientine Hydrochloride

Dosage Form : Hard Capsule Oral Use Bottle

Dosage Strength : 200 mg

Price Per Pack (Euro) : 3,782.79

Published in :

Country : Italy

RX/OTC/DISCN :

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02

Brand Name : TRIENTINA WAYMADE

United Kingdom
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CPHI Middle east
Not Confirmed

Brand Name : TRIENTINA WAYMADE

United Kingdom
arrow
CPHI Middle east
Not Confirmed

Trientine Hydrochloride

Dosage Form : Hard Capsules

Dosage Strength : 200 mg

Price Per Pack (Euro) : 2,647.95

Published in :

Country : Italy

RX/OTC/DISCN :

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03

Brand Name : Wilentin

Country
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CPHI Middle east
Not Confirmed

Brand Name : Wilentin

Country
arrow
CPHI Middle east
Not Confirmed

Trientine Hydrochloride

Dosage Form : Caps

Dosage Strength : 250mg

Price Per Pack (Euro) : 2314.55

Published in :

Country : Switzerland

RX/OTC/DISCN : Class B

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04

Brand Name : Triogen

Country
arrow
CPHI Middle east
Not Confirmed

Brand Name : Triogen

Country
arrow
CPHI Middle east
Not Confirmed

Trientine Hydrochloride

Dosage Form : Caps

Dosage Strength : 250mg

Price Per Pack (Euro) : 4117.12

Published in :

Country : Switzerland

RX/OTC/DISCN : Class B

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Annual Reports

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01

Brand Name : Syprine

Trientine Hydrochloride

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CPHI Middle east
Not Confirmed

Brand Name : Syprine

Canada
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CPHI Middle east
Not Confirmed

Trientine Hydrochloride

Main Therapeutic Indication : Genetic Disorders

Currency : USD

2016 Revenue in Millions : 88

2015 Revenue in Millions : 89

Growth (%) : -1

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02

Brand Name : Syprine

Trientine Hydrochloride

arrow
CPHI Middle east
Not Confirmed

Brand Name : Syprine

Canada
arrow
CPHI Middle east
Not Confirmed

Trientine Hydrochloride

Main Therapeutic Indication : Genetic Disorders

Currency : USD

2017 Revenue in Millions : 91

2016 Revenue in Millions : 88

Growth (%) : 3

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03

Brand Name : Syprine

Trientine Hydrochloride

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CPHI Middle east
Not Confirmed

Brand Name : Syprine

Canada
arrow
CPHI Middle east
Not Confirmed

Trientine Hydrochloride

Main Therapeutic Indication : Genetic Disorders

Currency : USD

2018 Revenue in Millions : 47

2017 Revenue in Millions : 91

Growth (%) : -48%

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Market Place

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FDF DOSSIERS

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REF. STANDARDS & IMPURITIES

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