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Chemistry

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Also known as: 6807-83-6, (-)-maackiain-3-o-glucoside, Chebi:9714, Trifolrhizin, (2r,3s,4s,5r,6s)-2-(hydroxymethyl)-6-[[(1r,12r)-5,7,11,19-tetraoxapentacyclo[10.8.0.02,10.04,8.013,18]icosa-2,4(8),9,13(18),14,16-hexaen-16-yl]oxy]oxane-3,4,5-triol, (-)-maackiain 3-o-glucoside
Molecular Formula
C22H22O10
Molecular Weight
446.4  g/mol
InChI Key
VGSYCWGXBYZLLE-QEEQPWONSA-N

Trifolirhizin
trifolirhizin is a natural product found in Sophora alopecuroides, Ononis arvensis, and other organisms with data available.
1 2D Structure

Trifolirhizin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[[(1R,12R)-5,7,11,19-tetraoxapentacyclo[10.8.0.02,10.04,8.013,18]icosa-2,4(8),9,13(18),14,16-hexaen-16-yl]oxy]oxane-3,4,5-triol
2.1.2 InChI
InChI=1S/C22H22O10/c23-6-17-18(24)19(25)20(26)22(32-17)30-9-1-2-10-13(3-9)27-7-12-11-4-15-16(29-8-28-15)5-14(11)31-21(10)12/h1-5,12,17-26H,6-8H2/t12-,17+,18+,19-,20+,21-,22+/m0/s1
2.1.3 InChI Key
VGSYCWGXBYZLLE-QEEQPWONSA-N
2.1.4 Canonical SMILES
C1C2C(C3=C(O1)C=C(C=C3)OC4C(C(C(C(O4)CO)O)O)O)OC5=CC6=C(C=C25)OCO6
2.1.5 Isomeric SMILES
C1[C@@H]2[C@H](C3=C(O1)C=C(C=C3)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)OC5=CC6=C(C=C25)OCO6
2.2 Synonyms
2.2.1 Depositor-Supplied Synonyms

1. 6807-83-6

2. (-)-maackiain-3-o-glucoside

3. Chebi:9714

4. Trifolrhizin

5. (2r,3s,4s,5r,6s)-2-(hydroxymethyl)-6-[[(1r,12r)-5,7,11,19-tetraoxapentacyclo[10.8.0.02,10.04,8.013,18]icosa-2,4(8),9,13(18),14,16-hexaen-16-yl]oxy]oxane-3,4,5-triol

6. (-)-maackiain 3-o-glucoside

7. Sophojaponicin B2

8. Chembl454878

9. Mfcd00238700

10. N1959

11. Acon1_002295

12. Dtxsid70987516

13. Hy-n0616

14. Zinc4098749

15. S9425

16. Akos030632879

17. Ccg-269193

18. Ncgc00169980-01

19. Ncgc00169980-03

20. Trifolirhizin, >=95% (lc/ms-elsd)

21. Beta-d-glucopyranoside, 6a,12a-dihydro-6h-(1,3)dioxolo(5,6)benzofuro(3,2-c)(1)benzopyran-3-yl, (6ar-cis)-

22. Trifolirhizin;(-)-maackiain-3-o-glucoside

23. Cs-0009612

24. 807t836

25. Q-100766

26. Brd-k43094903-001-01-3

27. Q27108480

28. (2s,3r,4s,5s,6r)-2-(((6ar,12ar)-6a,12a-dihydro-6h-[1,3]dioxolo[4',5':5,6]benzofuro[3,2-c]chromen-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2h-pyran-3,4,5-triol

29. Ncgc00169980-03_c22h22o10_beta-d-glucopyranoside, (6ar,12ar)-6a,12a-dihydro-6h-[1,3]dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-3-yl

2.3 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 446.4 g/mol
Molecular Formula C22H22O10
XLogP30.6
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count10
Rotatable Bond Count3
Exact Mass446.12129689 g/mol
Monoisotopic Mass446.12129689 g/mol
Topological Polar Surface Area136 Ų
Heavy Atom Count32
Formal Charge0
Complexity679
Isotope Atom Count0
Defined Atom Stereocenter Count7
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

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ABOUT THIS PAGE

Trifolirhizin Manufacturers

A Trifolirhizin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Trifolirhizin, including repackagers and relabelers. The FDA regulates Trifolirhizin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Trifolirhizin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Trifolirhizin Suppliers

A Trifolirhizin supplier is an individual or a company that provides Trifolirhizin active pharmaceutical ingredient (API) or Trifolirhizin finished formulations upon request. The Trifolirhizin suppliers may include Trifolirhizin API manufacturers, exporters, distributors and traders.

Trifolirhizin GMP

Trifolirhizin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Trifolirhizin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Trifolirhizin GMP manufacturer or Trifolirhizin GMP API supplier for your needs.

Trifolirhizin CoA

A Trifolirhizin CoA (Certificate of Analysis) is a formal document that attests to Trifolirhizin's compliance with Trifolirhizin specifications and serves as a tool for batch-level quality control.

Trifolirhizin CoA mostly includes findings from lab analyses of a specific batch. For each Trifolirhizin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Trifolirhizin may be tested according to a variety of international standards, such as European Pharmacopoeia (Trifolirhizin EP), Trifolirhizin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Trifolirhizin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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