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Chemistry

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Also known as: 6138-56-3, Tripelennamine (citrate), Nsc-757360, 2-(benzyl(2-(dimethylamino)ethyl)amino)pyridine citrate (1:1), 30oc46a3j9, 1,2-ethanediamine, n,n-dimethyl-n'-(phenylmethyl)-n'-2-pyridinyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
Molecular Formula
C22H29N3O7
Molecular Weight
447.5  g/mol
InChI Key
GGRBYIUPUOYRLQ-UHFFFAOYSA-N
FDA UNII
30OC46A3J9

Tripelennamine Citrate
A histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. It is used to treat ASTHMA; HAY FEVER; URTICARIA; and RHINITIS; and also in veterinary applications. Tripelennamine is administered by various routes, including topically.
1 2D Structure

Tripelennamine Citrate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
N'-benzyl-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine;2-hydroxypropane-1,2,3-tricarboxylic acid
2.1.2 InChI
InChI=1S/C16H21N3.C6H8O7/c1-18(2)12-13-19(16-10-6-7-11-17-16)14-15-8-4-3-5-9-15;7-3(8)1-6(13,5(11)12)2-4(9)10/h3-11H,12-14H2,1-2H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
2.1.3 InChI Key
GGRBYIUPUOYRLQ-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CN(C)CCN(CC1=CC=CC=C1)C2=CC=CC=N2.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
2.2 Other Identifiers
2.2.1 UNII
30OC46A3J9
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Azaron

2. Histantin

3. Pyribenzamine

4. Tripelennamine

5. Tripelennamine Citrate (1:1)

6. Tripelennamine Hydrochloride

7. Tripelennamine Maleate

8. Tripelennamine Maleate (1:1)

9. Tripelennamine Monohydrochloride

10. Vetibenzamin

2.3.2 Depositor-Supplied Synonyms

1. 6138-56-3

2. Tripelennamine (citrate)

3. Nsc-757360

4. 2-(benzyl(2-(dimethylamino)ethyl)amino)pyridine Citrate (1:1)

5. 30oc46a3j9

6. 1,2-ethanediamine, N,n-dimethyl-n'-(phenylmethyl)-n'-2-pyridinyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)

7. Ncgc00095775-01

8. Dsstox_cid_25989

9. Dsstox_rid_81276

10. Dsstox_gsid_45989

11. N'-benzyl-n,n-dimethyl-n'-pyridin-2-ylethane-1,2-diamine;2-hydroxypropane-1,2,3-tricarboxylic Acid

12. Pyribenzamine Citrate

13. Cas-6138-56-3

14. Einecs 228-121-6

15. Tripelennamine Citrate [usp]

16. Unii-30oc46a3j9

17. Pbz (tn)

18. Schembl99166

19. Spectrum1500597

20. Chembl1200769

21. Dtxsid8045989

22. Hms501k16

23. Hms2092a14

24. Pharmakon1600-01500597

25. Tripelennamine Citrate [mi]

26. Tox21_111518

27. Ccg-39053

28. Hy-17428b

29. Nsc757360

30. Pyridine, 2-(benzyl(2-(dimethylamino)ethyl)amino)-, Citrate (1:1)

31. Tripelennamine Citrate [vandf]

32. Tox21_111518_1

33. Tripelennamine Citrate [mart.]

34. Nsc 757360

35. Tripelennamine Citrate [who-dd]

36. Ncgc00018125-05

37. Ncgc00095775-02

38. Tripelennamine Citrate [orange Book]

39. Cs-0030834

40. D06246

41. Sr-01000003013-4

42. Q27255968

43. 1,2-ethanediamine, N,n-dimethyl-n'-(phenylmethyl)-n'-2-pyridinyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1) (salt)

44. 1,2-ethanediamine, N1,n1-dimethyl-n2-(phenylmethyl)-n2-2-pyridinyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)

45. N\'-benzyl-n,n-dimethyl-n\'-pyridin-2-ylethane-1,2-diamine,2-hydroxypropane-1,2,3-tricarboxylic Acid

2.4 Create Date
2005-08-09
3 Chemical and Physical Properties
Molecular Weight 447.5 g/mol
Molecular Formula C22H29N3O7
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count10
Rotatable Bond Count11
Exact Mass447.20055027 g/mol
Monoisotopic Mass447.20055027 g/mol
Topological Polar Surface Area152 Ų
Heavy Atom Count32
Formal Charge0
Complexity464
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Allergic Agents

Agents that are used to treat allergic reactions. Most of these drugs act by preventing the release of inflammatory mediators or inhibiting the actions of released mediators on their target cells. (From AMA Drug Evaluations Annual, 1994, p475) (See all compounds classified as Anti-Allergic Agents.)


Histamine H1 Antagonists

Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood. (See all compounds classified as Histamine H1 Antagonists.)


ABOUT THIS PAGE

Looking for 6138-56-3 / Tripelennamine Citrate API manufacturers, exporters & distributors?

Tripelennamine Citrate manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Tripelennamine Citrate API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Tripelennamine Citrate manufacturer or Tripelennamine Citrate supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Tripelennamine Citrate manufacturer or Tripelennamine Citrate supplier.

PharmaCompass also assists you with knowing the Tripelennamine Citrate API Price utilized in the formulation of products. Tripelennamine Citrate API Price is not always fixed or binding as the Tripelennamine Citrate Price is obtained through a variety of data sources. The Tripelennamine Citrate Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Tripelennamine Citrate

Synonyms

6138-56-3, Tripelennamine (citrate), Nsc-757360, 2-(benzyl(2-(dimethylamino)ethyl)amino)pyridine citrate (1:1), 30oc46a3j9, 1,2-ethanediamine, n,n-dimethyl-n'-(phenylmethyl)-n'-2-pyridinyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)

Cas Number

6138-56-3

Unique Ingredient Identifier (UNII)

30OC46A3J9

About Tripelennamine Citrate

A histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. It is used to treat ASTHMA; HAY FEVER; URTICARIA; and RHINITIS; and also in veterinary applications. Tripelennamine is administered by various routes, including topically.

Tripelennamine Citrate Manufacturers

A Tripelennamine Citrate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Tripelennamine Citrate, including repackagers and relabelers. The FDA regulates Tripelennamine Citrate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Tripelennamine Citrate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Tripelennamine Citrate Suppliers

A Tripelennamine Citrate supplier is an individual or a company that provides Tripelennamine Citrate active pharmaceutical ingredient (API) or Tripelennamine Citrate finished formulations upon request. The Tripelennamine Citrate suppliers may include Tripelennamine Citrate API manufacturers, exporters, distributors and traders.

Tripelennamine Citrate GMP

Tripelennamine Citrate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Tripelennamine Citrate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Tripelennamine Citrate GMP manufacturer or Tripelennamine Citrate GMP API supplier for your needs.

Tripelennamine Citrate CoA

A Tripelennamine Citrate CoA (Certificate of Analysis) is a formal document that attests to Tripelennamine Citrate's compliance with Tripelennamine Citrate specifications and serves as a tool for batch-level quality control.

Tripelennamine Citrate CoA mostly includes findings from lab analyses of a specific batch. For each Tripelennamine Citrate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Tripelennamine Citrate may be tested according to a variety of international standards, such as European Pharmacopoeia (Tripelennamine Citrate EP), Tripelennamine Citrate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Tripelennamine Citrate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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