EUROAPI, the leading small molecules API player, provides both API sales & CDMO services.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

3 API Suppliers, 1 USDMF, 2 Listed Suppliers

3 API Suppliers
1 USDMF
2 Listed Suppliers

MARKET PLACE

1 APIs

marketPlace
1 APIs

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: 1185-53-1, Tris hydrochloride, Tris(hydroxymethyl)aminomethane hydrochloride, Tromethamine hydrochloride, Tris hcl, Tris-hcl

Molecular Formula

C₄H₁₂ClNO₃

Molecular Weight

157.59 g/mol

InChI Key

QKNYBSVHEMOAJP-UHFFFAOYSA-N

FDA UNII

383V75M34E

1 2D Structure

Tris Hydrochloride API

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

2-amino-2-(hydroxymethyl)propane-1,3-diol;hydrochloride

2.1.2 InChI

InChI=1S/C4H11NO3.ClH/c5-4(1-6,2-7)3-8;/h6-8H,1-3,5H2;1H

2.1.3 InChI Key

QKNYBSVHEMOAJP-UHFFFAOYSA-N

2.1.4 Canonical SMILES

C(C(CO)(CO)N)O.Cl

2.2 Other Identifiers

2.2.1 UNII

383V75M34E

2.3 Synonyms

2.3.1 Depositor-Supplied Synonyms

1. 1185-53-1

2. Tris Hydrochloride

3. Tris(hydroxymethyl)aminomethane Hydrochloride

4. Tromethamine Hydrochloride

5. Tris Hcl

6. Tris-hcl

7. Trometamol Hydrochloride

8. 2-amino-2-(hydroxymethyl)-1,3-propanediol Hydrochloride

9. Tromethamine Hcl

10. Trometamol (hydrochloride)

11. Trizma Hydrochloride

12. 1,3-propanediol, 2-amino-2-(hydroxymethyl)-, Hydrochloride

13. Mfcd00012590

14. Trizma(r) Hydrochloride

15. Tromethamine (hydrochloride)

16. Tris Hydrochloride Solution, Ph 7.4

17. 2-amino-2-hydroxymethyl-1,3-propanediol Hydrochloride

18. 383v75m34e

19. 1185-53-1 (solid)

20. Tris Chloride

21. 1,3-propanediol, 2-amino-2-(hydroxymethyl)-, Hydrochloride (1:1)

22. Tris Hydrochloride Buffer

23. Trishydrochloride

24. Trishcl

25. Unii-383v75m34e

26. Tris.hcl

27. Tris, Hydrochloride

28. Einecs 214-684-5

29. Tham Hcl

30. Tris Hydrochloric Acid

31. Tromethane Hydrochloride

32. Tris(hydroxymethyl) Aminomethane Hydrochloride

33. Schembl2188

34. Dsstox_cid_24373

35. Dsstox_rid_80179

36. Tris Hcl, Biochemical Grade

37. Dsstox_gsid_44373

38. Tris Hydrochloride 12kg

39. Trizma(r) Hydrochloride, 99%

40. Chembl3183206

41. Dtxsid4044373

42. Tris Hcl (tris(hydroxymethyl)aminomethane Hydrochloride)

43. Hy-d0227a

44. Trizma(r) Hydrochloride, >=99%

45. Trimethylolaminomethane Hydrochloride

46. Tox21_302157

47. S5300

48. Tris Hydrochloride Solution, Ph 7.2

49. Tris Hydrochloride Solution, Ph 7.6

50. Tris Hydrochloride Solution, Ph 7.8

51. Tris Hydrochloride Solution, Ph 8.0

52. Akos015900319

53. Trizma(r) Buffer Substance, Ph 7.0

54. Trizma(r) Buffer Substance, Ph 7.2

55. Trizma(r) Buffer Substance, Ph 7.4

56. Trizma(r) Buffer Substance, Ph 7.5

57. Trizma(r) Buffer Substance, Ph 7.6

58. Trizma(r) Buffer Substance, Ph 7.7

59. Trizma(r) Buffer Substance, Ph 7.8

60. Trizma(r) Buffer Substance, Ph 8.0

61. Trizma(r) Buffer Substance, Ph 8.1

62. Trizma(r) Buffer Substance, Ph 8.3

63. Trizma(r) Buffer Substance, Ph 8.8

64. Trizma(r) Buffer Substance, Ph 9.0

65. Cs-w009054

66. Ncgc00255774-01

67. Trometamol Hydrochloride [who-dd]

68. As-83427

69. Bp-31026

70. Sy001400

71. Cas-1185-53-1

72. Tris(hydroxymethyl)methylamine Hydrochloride

73. Db-041414

74. B7299

75. Cs-0201545

76. Cs-0201546

77. Ft-0633430

78. T0740

79. Tris, Hydrochloride (molecular Biology Grade)

80. F20293

81. M02622

82. Tris (hydroxymethyl) Aminomethane Hydrochloride

83. Trizma(r) Hydrochloride Solution, 1 M, Ph 7.0

84. Trizma(r) Hydrochloride Solution, Ph 7.2, 1 M

85. Trizma(r) Hydrochloride Solution, Ph 7.6, 1 M

86. J-003844

87. J-507749

88. Q27256734

89. Tris-hcl-tris-hydroxymethyl-aminomethane-hydrochloride

90. Trizma(r) Hydrochloride, For Electrophoresis, >=99%

91. 2-amino-2-(hydroxymethyl)-1,3-propanediol Hcl

92. Trizma(r) Buffer Substance, For Fish-farming, Ph 8.3

93. 2-amino-2-(hydroxymethyl)-1, 3-propanediol Hydrochloride

94. Tris Hcl (tris(hydroxymethyl) Aminomethane Hydrochloride)

95. Trizma(r) Hydrochloride, Vetec(tm) Reagent Grade, >=99%

96. Tris(hydroxymethyl)aminomethane Hydrochloride Solution, Ph 7.2

97. Tris(hydroxymethyl)aminomethane Hydrochloride Solution, Ph 7.4

98. Tris(hydroxymethyl)aminomethane Hydrochloride Solution, Ph 7.6

99. Tris(hydroxymethyl)aminomethane Hydrochloride Solution, Ph 7.8

100. Tris(hydroxymethyl)aminomethane Hydrochloride Solution, Ph 8.0

101. Trizma(r) Hydrochloride, Bioultra, For Luminescence, >=99.0% (at)

102. Tris(hydroxymethyl)aminomethane Hydrochloride, 1m Stock Solution, Ph 8.0

103. Trizma(r) Hydrochloride, Anhydrous, Free-flowing, Redi-dri(tm), >=99.0%

104. Trizma(r) Hydrochloride, Bioultra, For Molecular Biology, >=99.0% (at)

105. Trizma(r) Hydrochloride, Reagent Grade, >=99.0% (titration), Crystalline

106. Tris(hydroxymethyl)aminomethane Hydrochloride, 1m Solution, Ph 7,4, Rnase Free

107. Tris(hydroxymethyl)aminomethane Hydrochloride, 1m Solution, Ph 8.0, Rnase Free

108. Trizma(r) Hydrochloride Buffer Solution, Bioultra, For Molecular Biology, Ph 7.2

109. Trizma(r) Hydrochloride Buffer Solution, Bioultra, For Molecular Biology, Ph 7.4

110. Trizma(r) Hydrochloride Buffer Solution, Bioultra, For Molecular Biology, Ph 7.6

111. Trizma(r) Hydrochloride Buffer Solution, Bioultra, For Molecular Biology, Ph 8.0

112. Trizma(r) Hydrochloride Solution, Ph 7.4, 1 M, Bioreagent, For Molecular Biology

113. Trizma(r) Hydrochloride Solution, Ph 8.0, 1 M, Bioreagent, For Molecular Biology

114. Trizma(r) Hydrochloride, Bioperformance Certified, Cell Culture Tested, >=99.0% (titration)

115. Trizma(r) Hydrochloride, Bioxtra, Ph 3.5-5.0 (0.5 M In H2o), >=99.0% (titration)

116. Tris Hydrochloride, Pharmagrade, Manufactured Under Appropriate Controls For Use As A Raw Material In Pharma Or Biopharmaceutical Production, Suitable For Cell Culture

117. Tris Hydrochloride, Pharmagrade, Manufactured Under Appropriate Controls For Use As A Raw Material In Pharma Or Biopharmaceutical Production., Suitable For Cell Culture

118. Tris(hydroxymethyl)aminomethane Hydrochloride, Inverted Exclamation Marky99%,for Molecular Biology

2.4 Create Date

2005-08-08

3 Chemical and Physical Properties

Molecular Formula	C₄H₁₂ClNO₃
Molecular Weight	157.59 g/mol
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Exact Mass	157.0505709 g/mol
Monoisotopic Mass	157.0505709 g/mol
Topological Polar Surface Area	86.7 Å²
Heavy Atom Count	9
Formal Charge	0
Complexity	54
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2