Find Trisalicylate-Choline manufacturers, exporters & distributors on PharmaCompass

PharmaCompass

Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

0

CEP/COS

CEP/COS Certifications

0

JDMF

JDMFs Filed

0

EU WC

EU WC

0

KDMF

KDMF

0

NDC API

NDC API

0

VMF

NDC API

0

Listed Suppliers

Other Suppliers

API REF. PRICE (USD/KG)

$
$ 0

MARKET PLACE

0

API

0

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

0

FDF Dossiers

FDF Dossiers

0

FDA Orange Book

FDA (Orange Book)

0

Europe

Europe

0

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

0

Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

0

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid

NA

Annual Reports

NA

Finished Drug Prices

NA

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: 64425-90-7, Djj95fjp1h, Choline magnesium salicylate, Cholinemagnesiumtrisalicylate, Trisalicylate-choline, Tegunor
Molecular Formula
C26H29MgNO10
Molecular Weight
539.8  g/mol
InChI Key
FQCQGOZEWWPOKI-UHFFFAOYSA-K
FDA UNII
DJJ95FJP1H

Trisalicylate-Choline
Choline Magnesium Trisalicylate is a nonsteroidal anti-inflammatory drug (NSAID) belonging to the salicylate family. Choline magnesium trisalicylate inhibits inflammation-related prostaglandin synthesis. This agent's analgesic effect is mediated through peripheral and central pathways, resulting in a decrease in pain perception; its antipyretic effect is mediated via the hypothalamic heat regulation center. (NCI04)
1 2D Structure

Trisalicylate-Choline

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
magnesium;2-carboxyphenolate;2-hydroxyethyl(trimethyl)azanium
2.1.2 InChI
InChI=1S/3C7H6O3.C5H14NO.Mg/c3*8-6-4-2-1-3-5(6)7(9)10;1-6(2,3)4-5-7;/h3*1-4,8H,(H,9,10);7H,4-5H2,1-3H3;/q;;;+1;+2/p-3
2.1.3 InChI Key
FQCQGOZEWWPOKI-UHFFFAOYSA-K
2.1.4 Canonical SMILES
C[N+](C)(C)CCO.C1=CC=C(C(=C1)C(=O)O)[O-].C1=CC=C(C(=C1)C(=O)O)[O-].C1=CC=C(C(=C1)C(=O)O)[O-].[Mg+2]
2.2 Other Identifiers
2.2.1 UNII
DJJ95FJP1H
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Tegunor

2. Tricosal

3. Trilisate

2.3.2 Depositor-Supplied Synonyms

1. 64425-90-7

2. Djj95fjp1h

3. Choline Magnesium Salicylate

4. Cholinemagnesiumtrisalicylate

5. Trisalicylate-choline

6. Tegunor

7. Tricolsal

8. Unii-djj95fjp1h

9. Tricosal (tn)

10. Choline Mixture With Magnesium Salicylate

11. Dtxsid901344133

12. Db01401

13. Nsc 751675

14. D07694

15. Choline Magnesium Trisalicylate [who-dd]

16. Q20817211

17. ((1,2-ethanediylbis(carbamodithioato))(2-))manganese, Mixt. With ((1,2-ethanediylbis(carbamodithioato))(2-))zinc & 2(or 4)-isooctyl-4,6(or 2,6)-dinitrophenyl 2-buten Oate

18. Ethanaminium, 2-hydroxy-n,n,n-trimethyl-, 2-hydroxybenzoate (1:1), Mixt. With (t-4)-bis(2-(hydroxy-.kappa.o)benzoato-.kappa.o)magnesium

19. Ethanaminium, 2-hydroxy-n,n,n-trimethyl-, Salt With 2-hydroxybenzoic Acid (1:1), Mixt. With 2-hydroxybenzoic Acid Magnesium Salt (2:1)

2.4 Create Date
2011-12-26
3 Chemical and Physical Properties
Molecular Weight 539.8 g/mol
Molecular Formula C26H29MgNO10
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count10
Rotatable Bond Count5
Exact Mass539.1641878 g/mol
Monoisotopic Mass539.1641878 g/mol
Topological Polar Surface Area201 Ų
Heavy Atom Count38
Formal Charge0
Complexity179
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count5
4 Drug and Medication Information
4.1 Drug Indication

Choline magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults.


5 Pharmacology and Biochemistry
5.1 Pharmacology

Trisalicylate-choline is a non-steroidal anti-inflammatory drug (NSAID) that contains a combination of choline salicylate and magnesium salicylate. Does not affect platelet aggregation.


5.2 MeSH Pharmacological Classification

Analgesics

Compounds capable of relieving pain without the loss of CONSCIOUSNESS. (See all compounds classified as Analgesics.)


Anti-Inflammatory Agents, Non-Steroidal

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)


5.3 Absorption, Distribution and Excretion

Route of Elimination

renal


5.4 Mechanism of Action

Inhibits prostaglandin synthesis; acts on the hypothalamus heat-regulating center to reduce fever; blocks the generation of pain impulses


API SUPPLIERS

read-more
read-more
Full Screen ViewFULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

ABOUT THIS PAGE

Trisalicylate-Choline Manufacturers

A Trisalicylate-Choline manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Trisalicylate-Choline, including repackagers and relabelers. The FDA regulates Trisalicylate-Choline manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Trisalicylate-Choline API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Trisalicylate-Choline Suppliers

A Trisalicylate-Choline supplier is an individual or a company that provides Trisalicylate-Choline active pharmaceutical ingredient (API) or Trisalicylate-Choline finished formulations upon request. The Trisalicylate-Choline suppliers may include Trisalicylate-Choline API manufacturers, exporters, distributors and traders.

click here to find a list of Trisalicylate-Choline suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Trisalicylate-Choline USDMF

A Trisalicylate-Choline DMF (Drug Master File) is a document detailing the whole manufacturing process of Trisalicylate-Choline active pharmaceutical ingredient (API) in detail. Different forms of Trisalicylate-Choline DMFs exist exist since differing nations have different regulations, such as Trisalicylate-Choline USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Trisalicylate-Choline DMF submitted to regulatory agencies in the US is known as a USDMF. Trisalicylate-Choline USDMF includes data on Trisalicylate-Choline's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Trisalicylate-Choline USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Trisalicylate-Choline suppliers with USDMF on PharmaCompass.

Trisalicylate-Choline GMP

Trisalicylate-Choline Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Trisalicylate-Choline GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Trisalicylate-Choline GMP manufacturer or Trisalicylate-Choline GMP API supplier for your needs.

Trisalicylate-Choline CoA

A Trisalicylate-Choline CoA (Certificate of Analysis) is a formal document that attests to Trisalicylate-Choline's compliance with Trisalicylate-Choline specifications and serves as a tool for batch-level quality control.

Trisalicylate-Choline CoA mostly includes findings from lab analyses of a specific batch. For each Trisalicylate-Choline CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Trisalicylate-Choline may be tested according to a variety of international standards, such as European Pharmacopoeia (Trisalicylate-Choline EP), Trisalicylate-Choline JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Trisalicylate-Choline USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty