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ACTIVE PHARMA INGREDIENTS

5 API Suppliers, 3 USDMF, 1 JDMF, 3 NDC API, 2 Listed Suppliers, $ API Reference Price

5 API Suppliers
3 USDMF
1 JDMF
3 NDC API
2 Listed Suppliers
$ API Reference Price

RELATED EXCIPIENT COMPANIES

2 Rochem International Inc, 2 SPI Pharma, 1 DKSH, 3 Faran Shimi Pharmaceutical, 1 Boai NKY Pharmaceuticals Ltd, 2 Gangwal Healthcare, 1 Pfanstiehl, 1 ACG Worldwide, 5 Actylis, 3 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 11 BASF, 10 Corel Pharma Chem, 5 Gangwal Chemicals, 4 Ideal Cures Pvt Ltd, 13 Kerry, 3 Kima Chemical, 6 Lonza Capsugel, 10 Microlex e.U, 2 Novo Excipients, 1 Pharmatrans-Sanaq, 5 Pluviaendo, 1 Prachin Chemical, 1 Qianhao Chemical (Hebei) Co., Ltd, 1 Qualicaps, 13 Roquette, 6 Seppic, 2 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 1 Shijiazhuang Huaxu Pharmaceutical, 1 Sigachi Industries, 2 The Dow Chemical Company, 1 Vasa Pharmachem, 1 Zhejiang Huakang Pharmaceutical

EXCIPIENTS BY APPLICATIONS

44 Coating Systems & Additives, 25 Fillers, Diluents & Binders, 20 Controlled & Modified Release, 13 Lubricants & Glidants, 12 Taste Masking, 11 Film Formers & Plasticizers, 10 Direct Compression, 9 Parenteral, 9 Granulation, 9 Solubilizers, 9 Thickeners and Stabilizers, 5 Empty Capsules, 4 Chewable & Orodispersible Aids, 4 Vegetarian Capsules, 4 API Stability Enhancers, 4 Emulsifying Agents, 3 Co-Processed Excipients, 2 Disintegrants & Superdisintegrants, 2 Coloring Agents, 2 Topical, 1 Rheology Modifiers

MARKET PLACE

7 APIs

marketPlace
7 APIs

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 3

MARKET PLACE

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FDF

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Finished Drug Prices

121 RELATED EXCIPIENT COMPANIES

202EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: Sodium citrate dihydrate, 6132-04-3, Sodium citrate tribasic dihydrate, Sodium citrate hydrate, 1,2,3-propanetricarboxylic acid, 2-hydroxy-, trisodium salt, dihydrate, Citric acid trisodium salt dihydrate

Molecular Formula

C₆H₉Na₃O₉

Molecular Weight

294.10 g/mol

InChI Key

NLJMYIDDQXHKNR-UHFFFAOYSA-K

FDA UNII

B22547B95K

Sodium salts of citric acid that are used as buffers and food preservatives. They are used medically as anticoagulants in stored blood, and for urine alkalization in the prevention of KIDNEY STONES.

1 2D Structure

Trisodium Citrate Dihydrate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

trisodium;2-hydroxypropane-1,2,3-tricarboxylate;dihydrate

2.1.2 InChI

InChI=1S/C6H8O7.3Na.2H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;2*1H2/q;3*+1;;/p-3

2.1.3 InChI Key

NLJMYIDDQXHKNR-UHFFFAOYSA-K

2.1.4 Canonical SMILES

C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O.O.O.[Na+].[Na+].[Na+]

2.2 Other Identifiers

2.2.1 UNII

B22547B95K

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Anhydrous Sodium Citrate

2. Citra Ph

3. Monosodium Citrate

4. Sodium Citrate

5. Sodium Citrate Dihydrate

6. Sodium Citrate Monobasic

7. Sodium Citrate, Anhydrous

2.3.2 Depositor-Supplied Synonyms

1. Sodium Citrate Dihydrate

2. 6132-04-3

3. Sodium Citrate Tribasic Dihydrate

4. Sodium Citrate Hydrate

5. 1,2,3-propanetricarboxylic Acid, 2-hydroxy-, Trisodium Salt, Dihydrate

6. Citric Acid Trisodium Salt Dihydrate

7. Trisodium;2-hydroxypropane-1,2,3-tricarboxylate;dihydrate

8. Mfcd00150031

9. Trisodium 2-hydroxypropane-1,2,3-tricarboxylate Dihydrate

10. Sodium Citrate, Dihydrate

11. B22547b95k

12. Citric Acid, Trisodium Salt, Dihydrate

13. Sodium Citrate Hydrous

14. Trisodium Citrate Dihydrate;citric Acid Trisodium Salt Dihydrate

15. Mfcd00130806

16. Tri-sodium Citrate Dihydrate

17. Sodium 2-hydroxypropane-1,2,3-tricarboxylate Dihydrate

18. Sodiumcitrate

19. N-1560

20. Natrum Citricum

21. Tricitrasol (tn)

22. Sodium Citrate (tn)

23. Sodium Citrate [usp:jan]

24. Sodiumcitratetribasicdihydrate

25. Sodium Citrate [fhfi]

26. Dtxsid1049437

27. Sodium Citrate Hydrate (jp17)

28. Unii-b22547b95k

29. Chebi:32142

30. Trisodium Citrate Dihydrate, Acs

31. Sodium Citrate Hydrous [ii]

32. Sodium Citrate Hydrate [jan]

33. Sodium Citrate [ep Monograph]

34. Sodium Citrate Dihydrate [mi]

35. Akos025293920

36. Citronensaeure,trinatrium-salz-dihydrat

37. Sodium Citrate Dihydrate, >=99%, Fg

38. Sodium Citrate Dihydrate [vandf]

39. Trisodium Citrate Dihydrate [ii]

40. Bp-31019

41. Sodium Citrate Dihydrate [who-dd]

42. Citrate, 0.5m Buffer Solution, Ph 3.0

43. Citrate, 0.5m Buffer Solution, Ph 4.0

44. Citrate, 0.5m Buffer Solution, Ph 4.5

45. Citrate, 0.5m Buffer Solution, Ph 5.0

46. Citrate, 0.5m Buffer Solution, Ph 5.5

47. Citrate, 0.5m Buffer Solution, Ph 6.0

48. Sodium Citrate Tribasic Dihydrate, >=98%

49. Sodium Citrate Dihydrate, Acs Reagent Grade

50. Sodium Citrate, Dihydrate [who-ip]

51. D01781

52. Sodium Citrate Tribasic Dihydrate, Ar, >=99%

53. Sodium Citrate Tribasic Dihydrate, Lr, >=99%

54. Citric Acid Trisodium Salt Dihydrate Acs Reagent

55. Natrii Citras, Dehydrate [who-ip Latin]

56. A833161

57. A835986

58. Trisodium Citrate Dihydrate [usp Monograph]

59. Q22075862

60. Sodium Citrate Dihydrate Biochemical Grade, Fine Granular

61. Sodium Citrate Tribasic Dihydrate, Usp, 99.0-100.5%

62. Sodium Citrate Tribasic Dihydrate (molecular Biology Grade)

63. Sodium Citrate Tribasic Dihydrate, Acs Reagent, >=99.0%

64. Trisodium 2-oxidanylpropane-1,2,3-tricarboxylate Dihydrate

65. Citric Acid Trisodium Salt Dihydratetrisodium Citrate Dihydrate

66. Sodium Citrate Tribasic Dihydrate, Bioultra, >=99.0% (nt)

67. Sodium Citrate Tribasic Dihydrate, Insect Cell Culture Tested

68. Sodium Citrate Tribasic Dihydrate, Jis Special Grade, >=99.0%

69. Sodium Citrate Tribasic Dihydrate, P.a., Acs Reagent, 99.0%

70. Sodium Citrate Tribasic Dihydrate, Purum P.a., >=99.0% (nt)

71. Sodium Citrate Tribasic Dihydrate, Saj First Grade, >=99.0%

72. Sodium Citrate Tribasic Dihydrate, Tested According To Ph.eur.

73. Trisodium 2-hydroxypropane-1,2,3-tricarboxylate--water (1/2)

74. Trisodium Citrate Dihydrate, Meets Usp Testing Specifications

75. 2-hydroxy-1,2,3-propanetricarboxylic Acid Trisodium Salt Dihydrate

76. Sodium Citrate Tribasic Dihydrate, Bioxtra, >=99.0% (titration)

77. Sodium Citrate Tribasic Dihydrate, For Molecular Biology, >=99%

78. Sodium Citrate Tribasic Dihydrate, Vetec(tm) Reagent Grade, 98%

79. Sodium Citrate, United States Pharmacopeia (usp) Reference Standard

80. 1,2,3-propanetricarboxylic Acid, 2-hydroxy-, Sodium Salt, Dihydrate

81. Sodium Citrate Tribasic Dihydrate, P.a., Acs Reagent, Reag. Iso, 99-101%

82. 1,2,3-propanetricarboxylic Acid, 2-hydroxy-, Sodium Salt, Hydrate (1:3:2)

83. Sodium Citrate Tribasic Dihydrate, Bioultra, For Molecular Biology, >=99.5% (nt)

84. Sodium Citrate Tribasic Dihydrate, Puriss. P.a., Acs Reagent, >=99.0% (nt)

85. Sodium Citrate Tribasic Dihydrate, Suitable For Amino Acid Analysis, >=99.0%

86. Sodium Citrate, Pharmaceutical Secondary Standard; Certified Reference Material

87. Sodium Citrate Tribasic Dihydrate, Puriss. P.a., Acs Reagent, Reag. Iso, Reag. Ph. Eur., >=99.5%

88. Sodium Citrate Tribasic Dihydrate, Puriss., Meets Analytical Specification Of Ph. Eur., Bp, Usp, Fcc, E331, 99-100.5% (calc. To The Dried Substance)

89. Sodium Citrate Tribasic Dihydrate, Suitable For Amino Acid Analysis, >=98% (titration), Powder

2.4 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₆H₉Na₃O₉
Molecular Weight	294.10 g/mol
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	2
Exact Mass	293.99396471 g/mol
Monoisotopic Mass	293.99396471 g/mol
Topological Polar Surface Area	143 Å²
Heavy Atom Count	18
Formal Charge	0
Complexity	211
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	6

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Anticoagulants

Agents that prevent BLOOD CLOTTING. (See all compounds classified as Anticoagulants.)

Buffers

A chemical system that functions to control the levels of specific ions in solution. When the level of hydrogen ion in solution is controlled the system is called a pH buffer. (See all compounds classified as Buffers.)

Food Preservatives

Substances capable of inhibiting, retarding or arresting the process of fermentation, acidification or other deterioration of foods. (See all compounds classified as Food Preservatives.)

4.2 FDA Pharmacological Classification

4.2.1 Pharmacological Classes

Anti-coagulant [EPC]; Calcium Chelating Activity [MoA]; Calculi Dissolution Agent [EPC]; Decreased Coagulation Factor Activity [PE]; Acidifying Activity [MoA]

API SUPPLIERS

01

Merck Group

Germany

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Duphat

Not Confirmed

02

Jungbunzlauer International AG

Switzerland

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Duphat

Not Confirmed

03

ACS DOBFAR SPA

Italy

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Duphat

Not Confirmed

04

Dr. Paul Lohmann GmbH KG

Germany

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Duphat

Not Confirmed

05

Dr. Raju’s Pharma Solutions

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Duphat

Not Confirmed

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USDMF

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JDMF

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NDC API

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Listed Suppliers

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API Reference Price

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Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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ABOUT THIS PAGE

Trisodium Citrate Dihydrate Manufacturers

A Trisodium Citrate Dihydrate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Trisodium Citrate Dihydrate, including repackagers and relabelers. The FDA regulates Trisodium Citrate Dihydrate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Trisodium Citrate Dihydrate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Trisodium Citrate Dihydrate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Trisodium Citrate Dihydrate Suppliers

A Trisodium Citrate Dihydrate supplier is an individual or a company that provides Trisodium Citrate Dihydrate active pharmaceutical ingredient (API) or Trisodium Citrate Dihydrate finished formulations upon request. The Trisodium Citrate Dihydrate suppliers may include Trisodium Citrate Dihydrate API manufacturers, exporters, distributors and traders.

click here to find a list of Trisodium Citrate Dihydrate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Trisodium Citrate Dihydrate USDMF

A Trisodium Citrate Dihydrate DMF (Drug Master File) is a document detailing the whole manufacturing process of Trisodium Citrate Dihydrate active pharmaceutical ingredient (API) in detail. Different forms of Trisodium Citrate Dihydrate DMFs exist exist since differing nations have different regulations, such as Trisodium Citrate Dihydrate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Trisodium Citrate Dihydrate DMF submitted to regulatory agencies in the US is known as a USDMF. Trisodium Citrate Dihydrate USDMF includes data on Trisodium Citrate Dihydrate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Trisodium Citrate Dihydrate USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Trisodium Citrate Dihydrate suppliers with USDMF on PharmaCompass.

Trisodium Citrate Dihydrate JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Trisodium Citrate Dihydrate Drug Master File in Japan (Trisodium Citrate Dihydrate JDMF) empowers Trisodium Citrate Dihydrate API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Trisodium Citrate Dihydrate JDMF during the approval evaluation for pharmaceutical products. At the time of Trisodium Citrate Dihydrate JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Trisodium Citrate Dihydrate suppliers with JDMF on PharmaCompass.

Trisodium Citrate Dihydrate NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Trisodium Citrate Dihydrate as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Trisodium Citrate Dihydrate API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Trisodium Citrate Dihydrate as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Trisodium Citrate Dihydrate and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Trisodium Citrate Dihydrate NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Trisodium Citrate Dihydrate suppliers with NDC on PharmaCompass.

Trisodium Citrate Dihydrate GMP

Trisodium Citrate Dihydrate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Trisodium Citrate Dihydrate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Trisodium Citrate Dihydrate GMP manufacturer or Trisodium Citrate Dihydrate GMP API supplier for your needs.

Trisodium Citrate Dihydrate CoA

A Trisodium Citrate Dihydrate CoA (Certificate of Analysis) is a formal document that attests to Trisodium Citrate Dihydrate's compliance with Trisodium Citrate Dihydrate specifications and serves as a tool for batch-level quality control.

Trisodium Citrate Dihydrate CoA mostly includes findings from lab analyses of a specific batch. For each Trisodium Citrate Dihydrate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Trisodium Citrate Dihydrate may be tested according to a variety of international standards, such as European Pharmacopoeia (Trisodium Citrate Dihydrate EP), Trisodium Citrate Dihydrate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Trisodium Citrate Dihydrate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.

Find Trisodium Citrate Dihydrate manufacturers, exporters & distributors on PharmaCompass

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5 API Suppliers

3 USDMF

1 JDMF

3 NDC API

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44 Coating Systems & Additives

25 Fillers, Diluents & Binders

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$ 3

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