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1. Oleandocetin
2. Tao
3. Triacetyloleandomycin
1. Triacetyloleandomycin
2. Oleandomycin Triacetate
3. Oleandocetine
4. Cyclamycin
5. Tribiocillina
6. Oleandomycin Triacetyl Ester
7. 2751-09-9
8. Evramicina
9. Troleandomicina
10. Troleandomycine
11. Triocetin
12. Aovine
13. Troleandomycinum
14. Oleandomycin, Triacetate (ester)
15. Matromycin T
16. Oleandomycin Triacetate Ester
17. Triacetyloleandomycinum
18. Matromicina
19. Treolmicina
20. Oleandomycin (as Troleandomycin)
21. Chebi:45735
22. C4dz64560d
23. Nsc-108166
24. Ai3-50166
25. Tao
26. Triacetyloleandomycin (jan)
27. Triacetyloleandomycin [jan]
28. Oleandomycin, Triacetyl-
29. Triolan
30. Viamicina
31. Wytrion
32. Treis-micina
33. Wy 651
34. Acetyloleandomycin
35. Tao (van)
36. Tao (tn)
37. Prestwick3_000036
38. Troleandomycin [mi]
39. Troleandomycin (usan/inn)
40. Troleandomycin [inn]
41. Bspbio_000131
42. Troleandomycin [usan]
43. Troleandomycine [inn-french]
44. Troleandomycinum [inn-latin]
45. Schembl125071
46. Troleandomycin [vandf]
47. Unii-c4dz64560d
48. Troleandomicina [inn-spanish]
49. Triacetyl Ester Of Oleandomycin
50. Troleandomycin [mart.]
51. Bpbio1_000145
52. Chembl564085
53. T.a.o.
54. Troleandomycin [who-dd]
55. Dtxsid2023721
56. Hms2089b10
57. Hms2095g13
58. Hms3712g13
59. Fmoc-(r)-3-amino-5-hexenoicacid
60. Einecs 220-392-9
61. Troleandomycin [orange Book]
62. Bdbm50370258
63. Lmpk04000042
64. Troleandomycin [usp Impurity]
65. Troleandomycin [usan:usp:inn:ban]
66. Zinc169307271
67. Ccg-220036
68. Db13179
69. Nsc 108166
70. Ncgc00179654-01
71. Hy-108881
72. Ab00513798
73. Cs-0031241
74. D01322
75. Ab00513798-02
76. Oleandomycin (as Troleandomycin) [vandf]
77. Q1087499
78. Brd-k38310698-001-01-9
79. (3r,5r,6s,7r,8r,11r,12s,13r,14s,15s)-12-[(4-o-acetyl-2,6-dideoxy-3-o-methyl-alpha-l-arabino-hexopyranosyl)oxy]-14-{[2-o-acetyl-3,4,6-trideoxy-3-(dimethylamino)-beta-d-xylo-hexopyranosyl]oxy}-5,7,8,11,13,15-hexamethyl-4,10-dioxo-1,9-dioxaspiro[2.13]hexadecan-6-yl Acetate
80. [(3r,5s,6s,7r,8s,9r,12r,13s,14s,15r)-6-[(2s,3r,4s,6r)-3-acetyloxy-4-(dimethylamino)-6-methyloxan-2-yl]oxy-8-[(2r,4s,5s,6s)-5-acetyloxy-4-methoxy-6-methyloxan-2-yl]oxy-5,7,9,12,13,15-hexamethyl-10,16-dioxo-1,11-dioxaspiro[2.13]hexadecan-14-yl] Acetate
| Molecular Weight | 814.0 g/mol |
|---|---|
| Molecular Formula | C41H67NO15 |
| XLogP3 | 4.3 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 16 |
| Rotatable Bond Count | 12 |
| Exact Mass | 813.45107043 g/mol |
| Monoisotopic Mass | 813.45107043 g/mol |
| Topological Polar Surface Area | 184 Ų |
| Heavy Atom Count | 57 |
| Formal Charge | 0 |
| Complexity | 1430 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 18 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
For the treatment of bacterial infection.
Troleandomycin, like other macrolide antibiotics, inhibits bacterial protein synthesis to prevent growth.
Anti-Bacterial Agents
Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)
J - Antiinfectives for systemic use
J01 - Antibacterials for systemic use
J01F - Macrolides, lincosamides and streptogramins
J01FA - Macrolides
J01FA08 - Troleandomycin
Troleandomycin has known human metabolites that include [(3R,5S,6S,7R,8S,9R,12R,13S,14S,15R)-8-[(2R,4S,5S,6S)-5-acetyloxy-4-methoxy-6-methyloxan-2-yl]oxy-6-[(2S,3R,4S,6R)-3-acetyloxy-6-methyl-4-(methylamino)oxan-2-yl]oxy-5,7,9,12,13,15-hexamethyl-10,16-dioxo-1,11-dioxaspiro[2.13]hexadecan-14-yl] acetate.
S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560
As a macrolide, troleandomycin binds to the 50S subunit of the bacterial ribosome. This binding inhibits translocation of tRNA along the A, P, and E sites of the ribosome. With tRNA unable to move from site to site, amino acids cannot be deposited onto the polypeptide chain leading to failure of protein synthesis. Bacterial cell growth and duplication is inhibited without the ability to generate the necessary proteins.
ABOUT THIS PAGE
A Troleandomycin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Troleandomycin, including repackagers and relabelers. The FDA regulates Troleandomycin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Troleandomycin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Troleandomycin supplier is an individual or a company that provides Troleandomycin active pharmaceutical ingredient (API) or Troleandomycin finished formulations upon request. The Troleandomycin suppliers may include Troleandomycin API manufacturers, exporters, distributors and traders.
click here to find a list of Troleandomycin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
A Troleandomycin DMF (Drug Master File) is a document detailing the whole manufacturing process of Troleandomycin active pharmaceutical ingredient (API) in detail. Different forms of Troleandomycin DMFs exist exist since differing nations have different regulations, such as Troleandomycin USDMF, ASMF (EDMF), JDMF, CDMF, etc.
A Troleandomycin DMF submitted to regulatory agencies in the US is known as a USDMF. Troleandomycin USDMF includes data on Troleandomycin's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Troleandomycin USDMF is kept confidential to protect the manufacturer’s intellectual property.
click here to find a list of Troleandomycin suppliers with USDMF on PharmaCompass.
Troleandomycin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Troleandomycin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Troleandomycin GMP manufacturer or Troleandomycin GMP API supplier for your needs.
A Troleandomycin CoA (Certificate of Analysis) is a formal document that attests to Troleandomycin's compliance with Troleandomycin specifications and serves as a tool for batch-level quality control.
Troleandomycin CoA mostly includes findings from lab analyses of a specific batch. For each Troleandomycin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Troleandomycin may be tested according to a variety of international standards, such as European Pharmacopoeia (Troleandomycin EP), Troleandomycin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Troleandomycin USP).
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