Find Tropifexor manufacturers, exporters & distributors on PharmaCompass

PharmaCompass

Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

0

API Suppliers

API Suppliers

0

USDMF

US DMFs Filed

0

CEP/COS

CEP/COS Certifications

0

JDMF

JDMFs Filed

0

EU WC

EU WC

0

KDMF

KDMF

0

NDC API

NDC API

0

VMF

NDC API

0

Listed Suppliers

Other Suppliers

0INTERMEDIATES

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

FINISHED DOSAGE FORMULATIONS

0

FDF Dossiers

FDF Dossiers

0

FDA Orange Book

FDA (Orange Book)

0

Europe

Europe

0

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

0

Listed Dossiers

Listed Dossiers

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

API REF. PRICE (USD/KG)

$
$ 0

GLOBAL SALES INFORMATION

US Medicaid

NA

Annual Reports

NA

Regulatory FDF Prices

NA

API/FDF Prices: Book a Demo to
explore the features and consider
upgrading later

MARKET PLACE

0

API

0

FDF

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: 1383816-29-2, Ljn452, Nvp-ljn452-nxa, Ljn-452, Tropifexor [inn], Tropifexor [usan]
Molecular Formula
C29H25F4N3O5S
Molecular Weight
603.6  g/mol
InChI Key
VYLOOGHLKSNNEK-JWTNVVGKSA-N
FDA UNII
NMZ08KM76Z

Tropifexor
1 2D Structure

Tropifexor

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-[(1R,5S)-3-[[5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl]methoxy]-8-azabicyclo[3.2.1]octan-8-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid
2.1.2 InChI
InChI=1S/C29H25F4N3O5S/c30-21-9-15(27(37)38)10-23-25(21)34-28(42-23)36-16-7-8-17(36)12-18(11-16)39-13-20-24(35-41-26(20)14-5-6-14)19-3-1-2-4-22(19)40-29(31,32)33/h1-4,9-10,14,16-18H,5-8,11-13H2,(H,37,38)/t16-,17+,18?
2.1.3 InChI Key
VYLOOGHLKSNNEK-JWTNVVGKSA-N
2.1.4 Canonical SMILES
C1CC1C2=C(C(=NO2)C3=CC=CC=C3OC(F)(F)F)COC4CC5CCC(C4)N5C6=NC7=C(C=C(C=C7S6)C(=O)O)F
2.1.5 Isomeric SMILES
C1C[C@H]2CC(C[C@@H]1N2C3=NC4=C(C=C(C=C4S3)C(=O)O)F)OCC5=C(ON=C5C6=CC=CC=C6OC(F)(F)F)C7CC7
2.2 Other Identifiers
2.2.1 UNII
NMZ08KM76Z
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2-((1r,5s)-3-((5-cyclopropyl-3-(2-(trifluoromethoxy)phenyl)-1,2-oxazol-4-yl)methoxy)-8-azabicyclo(3.2.1)octan-8-yl)-4-fluoro-1,3-benzothiazole-6-carboxylic Acid

2. Ljn452

2.3.2 Depositor-Supplied Synonyms

1. 1383816-29-2

2. Ljn452

3. Nvp-ljn452-nxa

4. Ljn-452

5. Tropifexor [inn]

6. Tropifexor [usan]

7. Tropifexor (ljn452)

8. Nmz08km76z

9. 2-[(1r,3r,5s)-3-({5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl}methoxy)-8-azabicyclo[3.2.1]octan-8-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic Acid

10. Tropifexor (usan)

11. Rel-2-((1r,3r,5s)-3-((5-cyclopropyl-3-(2-(trifluoromethoxy)phenyl)isoxazol-4-yl)methoxy)-8-azabicyclo[3.2.1]octan-8-yl)-4-fluorobenzo[d]thiazole-6-carboxylic Acid

12. 2-((1r,5s)-3-((5-cyclopropyl-3-(2-(trifluoromethoxy)phenyl)-1,2-oxazol-4-yl)methoxy)-8-azabicyclo(3.2.1)octan-8-yl)-4-fluoro-1,3-benzothiazole-6-carboxylic Acid

13. 2-[(1r,5s)-3-[[5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl]methoxy]-8-azabicyclo[3.2.1]octan-8-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic Acid

14. Ljn452; Tropifexor

15. Tropifexor [usan:inn]

16. Unii-nmz08km76z

17. Gtpl9725

18. Chembl4298169

19. Schembl17848159

20. Schembl19178329

21. Schembl20788139

22. Dtxsid001100225

23. Amy16804

24. Ex-a1934

25. Bdbm50527040

26. Mfcd31619256

27. S8733

28. Who 10443

29. Akos037648712

30. Compound 1 [pmid: 29148806]

31. Cs-8153

32. Ac-30341

33. Bs-15324

34. Hy-107418

35. D11548

36. F53709

37. A903437

38. 1383819-10-0

39. 2-((1r,3r,5s)-3-((5-cyclopropyl-3-(2-(trifluoromethoxy)phenyl)-1,2-oxazol-4-yl)methoxy)-8- Azabicyclo(3.2.1)octan-8-yl)-4-fluoro-1,3-benzothiazole-6-carboxylic Acid

40. 2-((1r,5s)-3-((5-cyclopropyl-3-(2-(trifluoromethoxy)phenyl)isoxazol-4-yl)methoxy)-8-azabicyclo[3.2.1]octan-8-yl)-4-fluorobenzo[d]thiazole-6-carboxylic Acid

41. 2-[(3-endo)-3-[[5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-4-isoxazolyl]methoxy]-8-azabicyclo[3.2.1]oct-8-yl]-4-fluoro-6-benzothiazolecarboxylic Acid

42. 6-benzothiazolecarboxylic Acid, 2-((3-endo)-3-((5-cyclopropyl-3-(2- (trifluoromethoxy)phenyl)-4-isoxazolyl)methoxy)-8-azabicyclo(3.2.1)oct-8- Yl)-4-fluoro-

43. Gwf

2.4 Create Date
2016-08-06
3 Chemical and Physical Properties
Molecular Weight 603.6 g/mol
Molecular Formula C29H25F4N3O5S
XLogP36.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count13
Rotatable Bond Count8
Exact Mass603.14510473 g/mol
Monoisotopic Mass603.14510473 g/mol
Topological Polar Surface Area126 Ų
Heavy Atom Count42
Formal Charge0
Complexity979
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Indication

Treatment of non-alcoholic steatohepatitis (NASH)


Digital Content read-more

Create Content with PharmaCompass, ask us

NEWS #PharmaBuzz

read-more
read-more

ABOUT THIS PAGE

Looking for 1383819-10-0 / Tropifexor API manufacturers, exporters & distributors?

Tropifexor manufacturers, exporters & distributors 1

22

PharmaCompass offers a list of Tropifexor API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Tropifexor manufacturer or Tropifexor supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Tropifexor manufacturer or Tropifexor supplier.

PharmaCompass also assists you with knowing the Tropifexor API Price utilized in the formulation of products. Tropifexor API Price is not always fixed or binding as the Tropifexor Price is obtained through a variety of data sources. The Tropifexor Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Tropifexor

Synonyms

1383816-29-2, Ljn452, Nvp-ljn452-nxa, Ljn-452, Tropifexor [inn], Tropifexor [usan]

Cas Number

1383819-10-0

Unique Ingredient Identifier (UNII)

NMZ08KM76Z

Tropifexor Manufacturers

A Tropifexor manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Tropifexor, including repackagers and relabelers. The FDA regulates Tropifexor manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Tropifexor API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Tropifexor Suppliers

A Tropifexor supplier is an individual or a company that provides Tropifexor active pharmaceutical ingredient (API) or Tropifexor finished formulations upon request. The Tropifexor suppliers may include Tropifexor API manufacturers, exporters, distributors and traders.

Tropifexor GMP

Tropifexor Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Tropifexor GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Tropifexor GMP manufacturer or Tropifexor GMP API supplier for your needs.

Tropifexor CoA

A Tropifexor CoA (Certificate of Analysis) is a formal document that attests to Tropifexor's compliance with Tropifexor specifications and serves as a tool for batch-level quality control.

Tropifexor CoA mostly includes findings from lab analyses of a specific batch. For each Tropifexor CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Tropifexor may be tested according to a variety of international standards, such as European Pharmacopoeia (Tropifexor EP), Tropifexor JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Tropifexor USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty