Find TRV027 manufacturers, exporters & distributors on PharmaCompass

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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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JDMF

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Chemistry

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Also known as: Trv-120027, Trv027, Trv120027, Trv-027, Unii-j1j4p3pqzd, 1234510-46-3
Molecular Formula
C43H67N13O10
Molecular Weight
926.1  g/mol
InChI Key
XIEWFECSPPTVQN-KMIMAYJXSA-N
FDA UNII
J1J4P3PQZD

TRV027
TRV120027 has been used in trials studying the treatment of Heart Failure and Kidney Disease.
1 2D Structure

TRV027

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2R)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[2-(methylamino)acetyl]amino]pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]propanoic acid
2.1.2 InChI
InChI=1S/C43H67N13O10/c1-7-24(4)35(40(63)53-31(19-27-20-47-22-49-27)41(64)56-17-9-11-32(56)38(61)50-25(5)42(65)66)55-37(60)30(18-26-12-14-28(57)15-13-26)52-39(62)34(23(2)3)54-36(59)29(51-33(58)21-46-6)10-8-16-48-43(44)45/h12-15,20,22-25,29-32,34-35,46,57H,7-11,16-19,21H2,1-6H3,(H,47,49)(H,50,61)(H,51,58)(H,52,62)(H,53,63)(H,54,59)(H,55,60)(H,65,66)(H4,44,45,48)/t24-,25+,29-,30-,31-,32-,34-,35-/m0/s1
2.1.3 InChI Key
XIEWFECSPPTVQN-KMIMAYJXSA-N
2.1.4 Canonical SMILES
CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(C)C(=O)O)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)CNC
2.1.5 Isomeric SMILES
CC[C@H](C)[C@@H](C(=O)N[C@@H](CC1=CN=CN1)C(=O)N2CCC[C@H]2C(=O)N[C@H](C)C(=O)O)NC(=O)[C@H](CC3=CC=C(C=C3)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC
2.2 Other Identifiers
2.2.1 UNII
J1J4P3PQZD
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Sar-arg-val-tyr-ile-his-pro-ala-oh

2. Sarcosine-arginyl-valyl-tyrosyl-isoleucyl-histidyl-prolyl-alanine

3. Trv 027

4. Trv-027

5. Trv-120027

6. Trv027

7. Trv120027

2.3.2 Depositor-Supplied Synonyms

1. Trv-120027

2. Trv027

3. Trv120027

4. Trv-027

5. Unii-j1j4p3pqzd

6. 1234510-46-3

7. Trv 027

8. J1j4p3pqzd

9. Trv 120027

10. Sar-val-tyr-ile-his-pro-d-ala-oh

11. Gtpl6902

12. Chembl4297447

13. Trv 027 [who-dd]

14. Hy-p2141

15. Db12199

16. Cs-0109050

17. Q27281029

18. (2r)-2-[[(2s)-1-[(2s)-2-[[(2s,3s)-2-[[(2s)-2-[[(2s)-2-[[(2s)-5-(diaminomethylideneamino)-2-[[2-(methylamino)acetyl]amino]pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1h-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]propanoic Acid

2.4 Create Date
2005-08-09
3 Chemical and Physical Properties
Molecular Weight 926.1 g/mol
Molecular Formula C43H67N13O10
XLogP3-2.3
Hydrogen Bond Donor Count12
Hydrogen Bond Acceptor Count13
Rotatable Bond Count26
Exact Mass925.51338539 g/mol
Monoisotopic Mass925.51338539 g/mol
Topological Polar Surface Area358 Ų
Heavy Atom Count66
Formal Charge0
Complexity1690
Isotope Atom Count0
Defined Atom Stereocenter Count8
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

TRV027 Manufacturers

A TRV027 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of TRV027, including repackagers and relabelers. The FDA regulates TRV027 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. TRV027 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

TRV027 Suppliers

A TRV027 supplier is an individual or a company that provides TRV027 active pharmaceutical ingredient (API) or TRV027 finished formulations upon request. The TRV027 suppliers may include TRV027 API manufacturers, exporters, distributors and traders.

TRV027 GMP

TRV027 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of TRV027 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right TRV027 GMP manufacturer or TRV027 GMP API supplier for your needs.

TRV027 CoA

A TRV027 CoA (Certificate of Analysis) is a formal document that attests to TRV027's compliance with TRV027 specifications and serves as a tool for batch-level quality control.

TRV027 CoA mostly includes findings from lab analyses of a specific batch. For each TRV027 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

TRV027 may be tested according to a variety of international standards, such as European Pharmacopoeia (TRV027 EP), TRV027 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (TRV027 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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