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Chemistry

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Also known as: Trypsinogen from bovine pancreas, 9002-08-8, Einecs 232-651-3, (2s,5s,8s,11s,14s)-2-(4-aminobutyl)-14-((s)-2-((s)-1-((s)-2-aminopropanoyl)pyrrolidine-2-carboxamido)-3-phenylpropanamido)-5,8,11-tris(carboxymethyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazahexadecane-1,16-dioic acid
Molecular Formula
C39H55N9O17
Molecular Weight
921.9  g/mol
InChI Key
NDIORHLFYZGYPG-FNRPHRCSSA-N

Trypsinogen
The inactive proenzyme of trypsin secreted by the pancreas, activated in the duodenum via cleavage by enteropeptidase. (Stedman, 25th ed)
1 2D Structure

Trypsinogen

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-aminopropanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-3-carboxypropanoyl]amino]-3-carboxypropanoyl]amino]-3-carboxypropanoyl]amino]-3-carboxypropanoyl]amino]hexanoic acid
2.1.2 InChI
InChI=1S/C39H55N9O17/c1-19(41)38(63)48-13-7-11-27(48)37(62)47-22(14-20-8-3-2-4-9-20)32(57)43-24(16-29(51)52)34(59)45-26(18-31(55)56)36(61)46-25(17-30(53)54)35(60)44-23(15-28(49)50)33(58)42-21(39(64)65)10-5-6-12-40/h2-4,8-9,19,21-27H,5-7,10-18,40-41H2,1H3,(H,42,58)(H,43,57)(H,44,60)(H,45,59)(H,46,61)(H,47,62)(H,49,50)(H,51,52)(H,53,54)(H,55,56)(H,64,65)/t19-,21-,22-,23-,24-,25-,26-,27-/m0/s1
2.1.3 InChI Key
NDIORHLFYZGYPG-FNRPHRCSSA-N
2.1.4 Canonical SMILES
CC(C(=O)N1CCCC1C(=O)NC(CC2=CC=CC=C2)C(=O)NC(CC(=O)O)C(=O)NC(CC(=O)O)C(=O)NC(CC(=O)O)C(=O)NC(CC(=O)O)C(=O)NC(CCCCN)C(=O)O)N
2.1.5 Isomeric SMILES
C[C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)O)N
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Trypsinogen 1

2.2.2 Depositor-Supplied Synonyms

1. Trypsinogen From Bovine Pancreas

2. 9002-08-8

3. Einecs 232-651-3

4. (2s,5s,8s,11s,14s)-2-(4-aminobutyl)-14-((s)-2-((s)-1-((s)-2-aminopropanoyl)pyrrolidine-2-carboxamido)-3-phenylpropanamido)-5,8,11-tris(carboxymethyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazahexadecane-1,16-dioic Acid

2.3 Create Date
2015-11-11
3 Chemical and Physical Properties
Molecular Weight 921.9 g/mol
Molecular Formula C39H55N9O17
XLogP3-8.9
Hydrogen Bond Donor Count13
Hydrogen Bond Acceptor Count19
Rotatable Bond Count28
Exact Mass921.37159132 g/mol
Monoisotopic Mass921.37159132 g/mol
Topological Polar Surface Area433 Ų
Heavy Atom Count65
Formal Charge0
Complexity1770
Isotope Atom Count0
Defined Atom Stereocenter Count8
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

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Looking for 9002-08-8 / Trypsinogen API manufacturers, exporters & distributors?

Trypsinogen manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Trypsinogen API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Trypsinogen manufacturer or Trypsinogen supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Trypsinogen manufacturer or Trypsinogen supplier.

PharmaCompass also assists you with knowing the Trypsinogen API Price utilized in the formulation of products. Trypsinogen API Price is not always fixed or binding as the Trypsinogen Price is obtained through a variety of data sources. The Trypsinogen Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Trypsinogen

Synonyms

Trypsinogen from bovine pancreas, 9002-08-8, Einecs 232-651-3, (2s,5s,8s,11s,14s)-2-(4-aminobutyl)-14-((s)-2-((s)-1-((s)-2-aminopropanoyl)pyrrolidine-2-carboxamido)-3-phenylpropanamido)-5,8,11-tris(carboxymethyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazahexadecane-1,16-dioic acid

Cas Number

9002-08-8

About Trypsinogen

The inactive proenzyme of trypsin secreted by the pancreas, activated in the duodenum via cleavage by enteropeptidase. (Stedman, 25th ed)

Trypsinogen Manufacturers

A Trypsinogen manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Trypsinogen, including repackagers and relabelers. The FDA regulates Trypsinogen manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Trypsinogen API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Trypsinogen Suppliers

A Trypsinogen supplier is an individual or a company that provides Trypsinogen active pharmaceutical ingredient (API) or Trypsinogen finished formulations upon request. The Trypsinogen suppliers may include Trypsinogen API manufacturers, exporters, distributors and traders.

Trypsinogen GMP

Trypsinogen Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Trypsinogen GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Trypsinogen GMP manufacturer or Trypsinogen GMP API supplier for your needs.

Trypsinogen CoA

A Trypsinogen CoA (Certificate of Analysis) is a formal document that attests to Trypsinogen's compliance with Trypsinogen specifications and serves as a tool for batch-level quality control.

Trypsinogen CoA mostly includes findings from lab analyses of a specific batch. For each Trypsinogen CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Trypsinogen may be tested according to a variety of international standards, such as European Pharmacopoeia (Trypsinogen EP), Trypsinogen JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Trypsinogen USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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