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Chemistry

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Also known as: Pharmasin, Tylosin tartrate, 1405-54-5, Schembl14973663
Molecular Formula
C50H83NO23
Molecular Weight
1066.2  g/mol
InChI Key
ICVKYYINQHWDLM-YLNALPTESA-N

Tylosin Tartrate
Macrolide antibiotic obtained from cultures of Streptomyces fradiae. The drug is effective against many microorganisms in animals but not in humans.
1 2D Structure

Tylosin Tartrate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2R,3R)-2,3-dihydroxybutanedioic acid;2-[(4R,5S,7R,9R,11E,13E,16R)-6-[(2R,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-16-ethyl-4-hydroxy-15-[[(2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxymethyl]-5,9,13-trimethyl-2,10-dioxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde
2.1.2 InChI
InChI=1S/C46H77NO17.C4H6O6/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35;5-1(3(7)8)2(6)4(9)10/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3;1-2,5-6H,(H,7,8)(H,9,10)/b15-14+,23-18+;/t24-,25+,26-,27-,28+,29+,30?,32-,33-,35+,36-,37-,38-,39?,40-,41-,42-,43+,44+,45-,46-;1-,2-/m11/s1
2.1.3 InChI Key
ICVKYYINQHWDLM-YLNALPTESA-N
2.1.4 Canonical SMILES
CCC1C(C=C(C=CC(=O)C(CC(C(C(C(CC(=O)O1)O)C)OC2C(C(C(C(O2)C)OC3CC(C(C(O3)C)O)(C)O)N(C)C)O)CC=O)C)C)COC4C(C(C(C(O4)C)O)OC)OC.C(C(C(=O)O)O)(C(=O)O)O
2.1.5 Isomeric SMILES
CC[C@@H]1C(/C=C(/C=C/C(=O)[C@@H](C[C@@H](C([C@H]([C@@H](CC(=O)O1)O)C)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)O)N(C)C)O)CC=O)C)\C)CO[C@H]4[C@@H]([C@@H]([C@@H]([C@H](O4)C)O)OC)OC.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Fradizine

2. Hydrochloride, Tylosin

3. Tartrate, Tylosin

4. Tylan

5. Tylosin

6. Tylosin Hydrochloride

7. Tylosin Tartrate

8. Tylosin Tartrate (salt)

9. Tylosine

2.2.2 Depositor-Supplied Synonyms

1. Pharmasin

2. Tylosin Tartrate

3. 1405-54-5

4. Schembl14973663

2.3 Create Date
2006-04-28
3 Chemical and Physical Properties
Molecular Weight 1066.2 g/mol
Molecular Formula C50H83NO23
Hydrogen Bond Donor Count9
Hydrogen Bond Acceptor Count24
Rotatable Bond Count16
Exact Mass1065.53558789 g/mol
Monoisotopic Mass1065.53558789 g/mol
Topological Polar Surface Area354 Ų
Heavy Atom Count74
Formal Charge0
Complexity1700
Isotope Atom Count0
Defined Atom Stereocenter Count21
Undefined Atom Stereocenter Count2
Defined Bond Stereocenter Count2
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)


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CEP/COS

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SupplySide West 2024
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Certificate Number : R1-CEP 2007-304 - Rev 01

Status : Valid

Issue Date : 2018-03-21

Type : Chemical and TSE

Substance Number : 1274

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Certificate Number : R1-CEP 2003-258 - Rev 01

Status : Valid

Issue Date : 2018-02-26

Type : Chemical

Substance Number : 1274

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Certificate Number : R1-CEP 2001-186 - Rev 02

Status : Withdrawn by Holder

Issue Date : 2018-04-23

Type : Chemical

Substance Number : 1274

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API Reference Price

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Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1724178600,"product":"TYLOSIN TARTRATE (VET) I.P.","address":"118, SAI COMMERCIAL CENTRE, 1ST FLR","city":"GOVANDI (E), MUMBAI, MAHARASHTRA","supplier":"SHANDONG LUKANG SHELILE ","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"DOLPHIN INTERNATIONAL","customerCountry":"INDIA","quantity":"20.43","actualQuantity":"20.43","unit":"KGS","unitRateFc":"25.5","totalValueFC":"532.9","currency":"USD","unitRateINR":"2188","date":"21-Aug-2024","totalValueINR":"44701.39","totalValueInUsd":"532.9","indian_port":"JNPT","hs_no":"29419090","bill_no":"5159877","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"50,HUALU ROAD,ZOUCHENG INDUSTRIAL PARK ZOUCHENG SHANDONG P.R CHINASDNF China","customerAddress":"118, SAI COMMERCIAL CENTRE, 1ST FLR"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1725215400,"product":"TYLOSIN TARTRATE IP (VET) (134 DRM) IUPAC NAME: (2R,3R)-2,3-DIHYDROXYBUTANEDIOIC ACID;2-[(4R,5S,7R,9R,11E,13E,16R)-6[(2RTYLOSIN TARTRATE IP (VET) (134 DRM) IUPAC NAME: (2R,3R)-2,3-","address":"304 AGGARWAL CITY SQUARE,MANGALAM","city":"DELHI,DELHI","supplier":"LONGCHEM INTERNATIONALTRADING COMPANY LIMITED","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"SHAH TC GLOBAL ","customerCountry":"INDIA","quantity":"2010.00","actualQuantity":"2010","unit":"KGS","unitRateFc":"25.5","totalValueFC":"51900.4","currency":"USD","unitRateINR":"2163.8","date":"02-Sep-2024","totalValueINR":"4349312.92","totalValueInUsd":"51900.4","indian_port":"ARSHIYA-SEZ\/PANVEL","hs_no":"29419090","bill_no":"5372444","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"UNIT 2 OF LG 1, MIRROR TOWER, 61 MO DY ROAD, TSIM SHA TSUI, KOWLOON HON G KONG Kowloon, , HONG KONG HONG KONG","customerAddress":"304 AGGARWAL CITY SQUARE,MANGALAM"}]
13-Jan-2021
02-Sep-2024
KGS
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country Total Quantity
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Average Price
(USD/KGS)
Number of Transactions

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