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Synopsis

ACTIVE PHARMA INGREDIENTS

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Chemistry

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Also known as: 80499-32-7, 80449-32-7, 3-(furan-2-yl)-2,4-dioxaspiro[5.5]undec-8-ene, Trypsin inhibitor (human urine urinastatin protein moiety), 3-(furan-2-yl)-2,4-dioxaspiro[5.5]undec-9-ene, 2,4-dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)-
Molecular Formula
C13H16O3
Molecular Weight
220.26  g/mol
InChI Key
ODVKSTFPQDVPJZ-UHFFFAOYSA-N

Urinastatin
1 2D Structure

Urinastatin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
3-(furan-2-yl)-2,4-dioxaspiro[5.5]undec-9-ene
2.1.2 InChI
InChI=1S/C13H16O3/c1-2-6-13(7-3-1)9-15-12(16-10-13)11-5-4-8-14-11/h1-2,4-5,8,12H,3,6-7,9-10H2
2.1.3 InChI Key
ODVKSTFPQDVPJZ-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1CC2(CC=C1)COC(OC2)C3=CC=CO3
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Acid-stable Protease Inhibitor

2. Miraclid

3. Mr 20

4. Mr 20 (magnetic Powder) Of Urinastatin

5. Mr-20 (magnetic Powder)

6. Trypsin Inhibitor Mr-20

7. Ulinastatin

8. Urinary Trypsin Inhibitor

9. Urinary Trypsin Inhibitor (68)

10. Urinary Trypsin Inhibitor-like Inhibitor (43)

11. Urinastatin

12. Uti(68)

13. Uti68

2.2.2 Depositor-Supplied Synonyms

1. 80499-32-7

2. 80449-32-7

3. 3-(furan-2-yl)-2,4-dioxaspiro[5.5]undec-8-ene

4. Trypsin Inhibitor (human Urine Urinastatin Protein Moiety)

5. 3-(furan-2-yl)-2,4-dioxaspiro[5.5]undec-9-ene

6. 2,4-dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)-

7. Trypsin Inhibitor Mr-20

8. Mr-20 (magnetic Powder)

9. Uti(68)

10. Acid-stable Protease Inhibitor

11. Urinary Trypsin Inhibitor (68)

12. Mr 20

13. Unii-or3s9if86u

14. Uristatin

15. Mingin

16. Urinary Trypsin Inhibitor-like Inhibitor (43)

17. Trypsin Inhibitor Uti

18. Ulinastatin [inn:jan]

19. Trypsin Inhibitor, Mingin

20. Trypsin Inhibitor, Bikunin

21. Urinary Trypsin Inhibitor 1

22. 3-(2-furanyl)-2,4-dioxaspiro(5.5)undec-8-ene

23. Dtxsid801001247

24. Bcp08067

25. Akos025401879

26. Ac-26827

27. Hy-21646

28. D77201

29. 9-(2-furyl)-8,10-dioxaspiro[5.5]undec-3-ene

2.3 Create Date
2005-08-01
3 Chemical and Physical Properties
Molecular Weight 220.26 g/mol
Molecular Formula C13H16O3
XLogP32.1
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Exact Mass220.109944368 g/mol
Monoisotopic Mass220.109944368 g/mol
Topological Polar Surface Area31.6 Ų
Heavy Atom Count16
Formal Charge0
Complexity266
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Trypsin Inhibitors

Serine proteinase inhibitors which inhibit trypsin. They may be endogenous or exogenous compounds. (See all compounds classified as Trypsin Inhibitors.)


API SUPPLIERS

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01

Guangzhou Tosun Pharmaceutical

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health
Not Confirmed
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02

Gufic Biosciences

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health
Not Confirmed
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Gufic Biosciences

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Medlab Asia & Asia Health
Not Confirmed
USDMF CEP/COS JDMF EU-WCInactive-api NDC KDMF VMF Others AUDIT
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03

Hanways Chempharm

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health
Not Confirmed
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EU WC

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01

Medlab Asia & Asia Health
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Medlab Asia & Asia Health
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ulinastatin JP

Date of Issue : 2021-04-12

Valid Till : 2024-01-28

Written Confirmation Number : WC-0256

Address of the Firm : N.H.8, Near Grid, Kabilpore, City Navasari-396424, Dist. Navsari, Gujarat

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KDMF

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01

Medlab Asia & Asia Health
Not Confirmed
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Medlab Asia & Asia Health
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Urinastatin

Registrant Name : Sampoong Finechem Co., Ltd.

Registration Date : 2021-06-30

Registration Number : 20210630-210-J-1047

Manufacturer Name : BSV BioScience GmbH

Manufacturer Address : Max-Planck-Strasse 12, 52499 Baesweiler, Germany

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Listed Suppliers

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01

Medlab Asia & Asia Health
Not Confirmed
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Medlab Asia & Asia Health
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Urinastatin

About the Company : Guangzhou Tosun Pharmaceutical was founded in 1999, which mainly focuses on importation & exportation of Active Pharmaceutical Ingrediants, Chemical Raw Materials, Intermediate, Ex...

Guangzhou Tosun Pharmaceutical was founded in 1999, which mainly focuses on importation & exportation of Active Pharmaceutical Ingrediants, Chemical Raw Materials, Intermediate, Excipients, Herbal extracts, Formulation of Chinese & Western Medicine. With abundant economic strength, the group has successfully developed to a pharmaceutical group enterprise wich intergrets operation of medicine & related products, processing & manufacturing, and importation & exportation together.
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02

Medlab Asia & Asia Health
Not Confirmed
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Medlab Asia & Asia Health
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Urinastatin

About the Company : Hanways Chempharm Co., Limited, the former one is Hubei Hanways Pharchem CO.,Limited, set up in 2009 in Wuhan, China. We are engaged in supplying APIs, pharmaceutical intermediate...

Hanways Chempharm Co., Limited, the former one is Hubei Hanways Pharchem CO.,Limited, set up in 2009 in Wuhan, China. We are engaged in supplying APIs, pharmaceutical intermediates, and fine chemicals for worldwide markets. With decades of development, now we grow to a leading and outstanding company. We are not just a trading company, but a comprehensive solutions supplier. With our sound knowledge of pharmaceutical business, our advantage is to integrate resources and adapt to all different demands of markets. We are a young but dynamic and energetic company with high efficient and high flexible decision making system.
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Drugs in Development

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Details:

The trial will involve approximately 120 patients who have mild to moderate symptoms of acute ARDS. The drug is expected to improve recovery time and also mitigate mortality rates.


Lead Product(s): Urinastatin

Therapeutic Area: Infections and Infectious Diseases Brand Name: Undisclosed

Study Phase: Phase IIIProduct Type: Large molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 09, 2020

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Medlab Asia & Asia Health
Not Confirmed
Medlab Asia & Asia Health
Not Confirmed

Details : The trial will involve approximately 120 patients who have mild to moderate symptoms of acute ARDS. The drug is expected to improve recovery time and also mitigate mortality rates.

Brand Name : Undisclosed

Molecule Type : Large molecule

Upfront Cash : Not Applicable

June 09, 2020

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REF. STANDARDS & IMPURITIES

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Medlab Asia & Asia Health
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Ulinastatin

Monograph in Japanese Pharmacopoeia : Ulinastati...

Package Size : 3700 Units

Price (¥) : 37,852

Storage Temprature °C : -20 to -30°C

Assay Test : A/ EA

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