DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

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Valsynthese, part of the SSE Group, is a CDMO focused on highly energetic and highly hazardous chemistry.

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CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

42 API Suppliers, 22 USDMF, 2 CEP/COS, 10 EU WC, 19 NDC API, 20 Listed Suppliers, $ API Reference Price

42 API Suppliers
22 USDMF
2 CEP/COS
10 EU WC
19 NDC API
20 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

24 Drugs in Development

24 Drugs in Development

INTERMEDIATES

9 Intermediates Suppliers

9 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

91 FDF Dossiers, 18 FDA Orange Book, 45 Europe, 6 Canada, 9 Australia, 5 South Africa, 8 Listed Dossiers

91 FDF Dossiers
18 FDA Orange Book
45 Europe
6 Canada
9 Australia
5 South Africa
8 Listed Dossiers

RELATED EXCIPIENT COMPANIES

5 Rochem International Inc, 15 SPI Pharma, 2 Seqens, 4 DKSH, 1 Pharm-RX Chemical, 5 Faran Shimi Pharmaceutical, 4 Boai NKY Pharmaceuticals Ltd, 8 Gangwal Healthcare, 5 Nanjing Well Pharmaceutical, 1 Pfanstiehl, 1 Capital Farma, 1 ACG Worldwide, 7 Actylis, 1 Aeon Procare, 4 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 1 Avesta Pharma, 24 BASF, 1 Bioplus Life Sciences, 2 Clariant, 10 Corel Pharma Chem, 2 DFE Pharma, 2 Finar, 11 Gangwal Chemicals, 7 Ideal Cures Pvt Ltd, 1 Ingredion Pharma Solutions, 19 Kerry, 3 Kima Chemical, 6 Lonza Capsugel, 13 Microlex e.U, 1 Nanjing Bold Chemical, 2 Nomisma Healthcare, 3 Novo Excipients, 2 Pharmatrans-Sanaq, 5 Pluviaendo, 2 Prachin Chemical, 1 Qianhao Chemical (Hebei) Co., Ltd, 1 Qualicaps, 19 Roquette, 14 Seppic, 5 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 1 Shanghai Welltone Material Technology Co., Ltd, 1 Shijiazhuang Huaxu Pharmaceutical, 9 Sigachi Industries, 2 The Dow Chemical Company, 1 Ulanqab Kema New Material, 1 Valens Pharmachem, 2 Vasa Pharmachem

relatedExcipients
5 Rochem International Inc
15 SPI Pharma
2 Seqens
4 DKSH
1 Pharm-RX Chemical
5 Faran Shimi Pharmaceutical
4 Boai NKY Pharmaceuticals Ltd
8 Gangwal Healthcare
5 Nanjing Well Pharmaceutical
1 Pfanstiehl
1 Capital Farma
1 ACG Worldwide
7 Actylis
1 Aeon Procare
4 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd
1 Avesta Pharma
24 BASF
1 Bioplus Life Sciences
2 Clariant
10 Corel Pharma Chem
2 DFE Pharma
2 Finar
11 Gangwal Chemicals
7 Ideal Cures Pvt Ltd
1 Ingredion Pharma Solutions
19 Kerry
3 Kima Chemical
6 Lonza Capsugel
13 Microlex e.U
1 Nanjing Bold Chemical
2 Nomisma Healthcare
3 Novo Excipients
2 Pharmatrans-Sanaq
5 Pluviaendo
2 Prachin Chemical
1 Qianhao Chemical (Hebei) Co., Ltd
1 Qualicaps
19 Roquette
14 Seppic
5 Shanghai Shenmei Pharmaceutical Technology Co., Ltd
1 Shanghai Welltone Material Technology Co., Ltd
1 Shijiazhuang Huaxu Pharmaceutical
9 Sigachi Industries
2 The Dow Chemical Company
1 Ulanqab Kema New Material
1 Valens Pharmachem
2 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

60 Fillers, Diluents & Binders, 53 Coating Systems & Additives, 34 Solubilizers, 31 Controlled & Modified Release, 29 Direct Compression, 27 Thickeners and Stabilizers, 20 Parenteral, 20 Topical, 19 Taste Masking, 18 Lubricants & Glidants, 18 Granulation, 16 Film Formers & Plasticizers, 16 Co-Processed Excipients, 13 Chewable & Orodispersible Aids, 11 Emulsifying Agents, 9 API Stability Enhancers, 8 Disintegrants & Superdisintegrants, 6 Surfactant & Foaming Agents, 5 Empty Capsules, 4 Vegetarian Capsules, 4 Coloring Agents, 4 Rheology Modifiers

DIGITAL CONTENT

1 DATA COMPILATION #PharmaFlow, 31 NEWS #PharmaBuzz

media
1 DATA COMPILATION #PharmaFlow
31 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

2 US Medicaid Prescriptions, 16 Finished Drug Prices, 1 Annual Reports

globalSalesInformation
2 US Medicaid Prescriptions
16 Finished Drug Prices
1 Annual Reports

MARKET PLACE

8 APIs, 10 FDF Dossiers

marketPlace
8 APIs
10 FDF Dossiers

PATENTS & EXCLUSIVITIES

2 US Patents, 2 Health Canada Patents

patents
2 US Patents
2 Health Canada Patents

REF. STANDARDS & IMPURITIES

2 USP , 2 Others

otherSolutions
2 USP
2 Others

ANALYTICAL

1 BioAnalytical Methods

otherMethods
1 BioAnalytical Methods

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 1,787

MARKET PLACE

API

FDF

9INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

24DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

44,278,010

Annual Reports (USD Million)

733

Finished Drug Prices

238 RELATED EXCIPIENT COMPANIES

425EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as:

Molecular Formula

C₁₄H₂₃ClN₆O₅

Molecular Weight

390.82 g/mol

InChI Key

ZORWARFPXPVJLW-MTFPJWTKSA-N

1 2D Structure

Valganciclovir Hydrochloride

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

[2-[(2-amino-6-oxo-3H-purin-9-yl)methoxy]-3-hydroxypropyl] (2S)-2-amino-3-methylbutanoate;hydrochloride

2.1.2 InChI

InChI=1S/C14H22N6O5.ClH/c1-7(2)9(15)13(23)24-4-8(3-21)25-6-20-5-17-10-11(20)18-14(16)19-12(10)22;/h5,7-9,21H,3-4,6,15H2,1-2H3,(H3,16,18,19,22);1H/t8?,9-;/m0./s1

2.1.3 InChI Key

ZORWARFPXPVJLW-MTFPJWTKSA-N

2.1.4 Canonical SMILES

CC(C)C(C(=O)OCC(CO)OCN1C=NC2=C1NC(=NC2=O)N)N.Cl

2.1.5 Isomeric SMILES

CC(C)[C@@H](C(=O)OCC(CO)OCN1C=NC2=C1NC(=NC2=O)N)N.Cl

2.2 Create Date

2005-08-08

3 Chemical and Physical Properties

Molecular Formula	C₁₄H₂₃ClN₆O₅
Molecular Weight	390.82 g/mol
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	9
Exact Mass	390.1418455 g/mol
Monoisotopic Mass	390.1418455 g/mol
Topological Polar Surface Area	167 A^2
Heavy Atom Count	26
Formal Charge	0
Complexity	528
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 4
Drug Name	Valcyte
PubMed Health	Valganciclovir (By mouth)
Drug Classes	Antiviral
Drug Label	Valcyte contains valganciclovir hydrochloride (valganciclovir HCl), a hydrochloride salt of the L-valyl ester of ganciclovir that exists as a mixture of two diastereomers. Ganciclovir is a synthetic guanine derivative active against CMV.Valcyte is av...
Active Ingredient	Valganciclovir hydrochloride
Dosage Form	Tablet; For solution
Route	Oral
Strength	50mg/ml; eq 450mg base
Market Status	Prescription
Company	Hoffmann La Roche

2 of 4
Drug Name	Valganciclovir hydrochloride
Drug Label	Valcyte contains valganciclovir hydrochloride (valganciclovir HCl), a hydrochloride salt of the L-valyl ester of ganciclovir that exists as a mixture of two diastereomers. Ganciclovir is a synthetic guanine derivative active against CMV.Valcyte is av...
Active Ingredient	Valganciclovir hydrochloride
Dosage Form	Tablet
Route	oral
Strength	450mg
Market Status	Tentative Approval
Company	Ranbaxy

3 of 4
Drug Name	Valcyte
PubMed Health	Valganciclovir (By mouth)
Drug Classes	Antiviral
Drug Label	Valcyte contains valganciclovir hydrochloride (valganciclovir HCl), a hydrochloride salt of the L-valyl ester of ganciclovir that exists as a mixture of two diastereomers. Ganciclovir is a synthetic guanine derivative active against CMV.Valcyte is av...
Active Ingredient	Valganciclovir hydrochloride
Dosage Form	Tablet; For solution
Route	Oral
Strength	50mg/ml; eq 450mg base
Market Status	Prescription
Company	Hoffmann La Roche

4 of 4
Drug Name	Valganciclovir hydrochloride
Drug Label	Valcyte contains valganciclovir hydrochloride (valganciclovir HCl), a hydrochloride salt of the L-valyl ester of ganciclovir that exists as a mixture of two diastereomers. Ganciclovir is a synthetic guanine derivative active against CMV.Valcyte is av...
Active Ingredient	Valganciclovir hydrochloride
Dosage Form	Tablet
Route	oral
Strength	450mg
Market Status	Tentative Approval
Company	Ranbaxy

API SUPPLIERS

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USDMF

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CEP/COS

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EU WC

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NDC API

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Listed Suppliers

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API Reference Price

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