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Chemistry

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Also known as: Econor, 101312-92-9, 2ahc415bqg, [(1s,2r,3s,4s,6r,7r,8r,14r)-4-ethenyl-3-hydroxy-2,4,7,14-tetramethyl-9-oxo-6-tricyclo[5.4.3.01,8]tetradecanyl] 2-[1-[[(2r)-2-amino-3-methylbutanoyl]amino]-2-methylpropan-2-yl]sulfanylacetate, Acetic acid,[[2-[[(2r)-2-amino-3-methyl-1-oxobutyl]amino]-1,1-dimethylethyl]thio]-,(3as,4r,5s,6s,8r,9r,9ar,10r)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3ah-cyclopentacycloocten-8-ylester, Valnemulin [inn:ban]
Molecular Formula
C31H52N2O5S
Molecular Weight
564.8  g/mol
InChI Key
LLYYNOVSVPBRGV-MVNKZKPCSA-N
FDA UNII
2AHC415BQG

Valnemulin
1 2D Structure

Valnemulin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[(1S,2R,3S,4S,6R,7R,8R,14R)-4-ethenyl-3-hydroxy-2,4,7,14-tetramethyl-9-oxo-6-tricyclo[5.4.3.01,8]tetradecanyl] 2-[1-[[(2R)-2-amino-3-methylbutanoyl]amino]-2-methylpropan-2-yl]sulfanylacetate
2.1.2 InChI
InChI=1S/C31H52N2O5S/c1-10-29(8)15-22(38-23(35)16-39-28(6,7)17-33-27(37)24(32)18(2)3)30(9)19(4)11-13-31(20(5)26(29)36)14-12-21(34)25(30)31/h10,18-20,22,24-26,36H,1,11-17,32H2,2-9H3,(H,33,37)/t19-,20+,22-,24-,25+,26+,29-,30+,31+/m1/s1
2.1.3 InChI Key
LLYYNOVSVPBRGV-MVNKZKPCSA-N
2.1.4 Canonical SMILES
CC1CCC23CCC(=O)C2C1(C(CC(C(C3C)O)(C)C=C)OC(=O)CSC(C)(C)CNC(=O)C(C(C)C)N)C
2.1.5 Isomeric SMILES
C[C@@H]1CC[C@@]23CCC(=O)[C@H]2[C@@]1([C@@H](C[C@@]([C@H]([C@@H]3C)O)(C)C=C)OC(=O)CSC(C)(C)CNC(=O)[C@@H](C(C)C)N)C
2.2 Other Identifiers
2.2.1 UNII
2AHC415BQG
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Econor

2.3.2 Depositor-Supplied Synonyms

1. Econor

2. 101312-92-9

3. 2ahc415bqg

4. [(1s,2r,3s,4s,6r,7r,8r,14r)-4-ethenyl-3-hydroxy-2,4,7,14-tetramethyl-9-oxo-6-tricyclo[5.4.3.01,8]tetradecanyl] 2-[1-[[(2r)-2-amino-3-methylbutanoyl]amino]-2-methylpropan-2-yl]sulfanylacetate

5. Acetic Acid,[[2-[[(2r)-2-amino-3-methyl-1-oxobutyl]amino]-1,1-dimethylethyl]thio]-,(3as,4r,5s,6s,8r,9r,9ar,10r)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3ah-cyclopentacycloocten-8-ylester

6. Valnemulin [inn:ban]

7. Unii-2ahc415bqg

8. Ncgc00167968-01

9. Valnemulin [mi]

10. Valnemulin [mart.]

11. Dsstox_cid_26751

12. Dsstox_rid_81876

13. Dsstox_gsid_46751

14. Schembl216709

15. Chembl1688852

16. Dtxsid2046751

17. (hydroxy-tetramethyl-oxo-vinyl-[?]yl) 2-[2-[[(2r)-2-amino-3-methyl-butanoyl]amino]-1,1-dimethyl-ethyl]sulfanylacetate

18. Tox21_112596

19. Zinc30727788

20. Valnemulin [ema Epar Veterinary]

21. ((2-((r)-2-amino-3-methylbutyramido)-1,1-dimethylethyl)thio)acetic Acid, 8-ester With (3as,4r,5s,6s,8r,9r,9ar,10r)-octahydro-5,8-dihydroxy-4,6,9,10-tetramethyl-6-vinyl-3a,9-propano-3ah-cyclopentacycloocten-1(4h)-one

22. Cas-101312-92-9

23. Ab01566922_01

24. Q7912519

2.4 Create Date
2006-10-25
3 Chemical and Physical Properties
Molecular Weight 564.8 g/mol
Molecular Formula C31H52N2O5S
XLogP35.3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count10
Exact Mass564.35969394 g/mol
Monoisotopic Mass564.35969394 g/mol
Topological Polar Surface Area144 Ų
Heavy Atom Count39
Formal Charge0
Complexity969
Isotope Atom Count0
Defined Atom Stereocenter Count9
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Indication

* Pigs:

The treatment and prevention of swine dysentery. The treatment of clinical signs of porcine proliferative enteropathy (ileitis). The prevention of clinical signs of porcine colonic spirochaetosis (colitis) when the disease has been diagnosed in the herd. Treatment and prevention of swine enzootic pneumonia. At the recommended dosage of 1012 mg/kg bodyweight lung lesions and weight loss are reduced, but infection with Mycoplasma hyopneumoniae is not eliminated.

* Rabbits:

Reduction of mortality during an outbreak of epizootic rabbit enteropathy (ERE). Treatment should be started early in the outbreak, when the first rabbit has been diagnosed with the disease clinically.


5 Pharmacology and Biochemistry
5.1 ATC Code

QJ01XQ02


API SUPPLIERS

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ABOUT THIS PAGE

Valnemulin Manufacturers

A Valnemulin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Valnemulin, including repackagers and relabelers. The FDA regulates Valnemulin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Valnemulin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Valnemulin manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Valnemulin Suppliers

A Valnemulin supplier is an individual or a company that provides Valnemulin active pharmaceutical ingredient (API) or Valnemulin finished formulations upon request. The Valnemulin suppliers may include Valnemulin API manufacturers, exporters, distributors and traders.

click here to find a list of Valnemulin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Valnemulin GMP

Valnemulin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Valnemulin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Valnemulin GMP manufacturer or Valnemulin GMP API supplier for your needs.

Valnemulin CoA

A Valnemulin CoA (Certificate of Analysis) is a formal document that attests to Valnemulin's compliance with Valnemulin specifications and serves as a tool for batch-level quality control.

Valnemulin CoA mostly includes findings from lab analyses of a specific batch. For each Valnemulin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Valnemulin may be tested according to a variety of international standards, such as European Pharmacopoeia (Valnemulin EP), Valnemulin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Valnemulin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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