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Chemistry

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Also known as: 33433-82-8, Valproic acid calcium salt, Valproate calcium, Calcium;2-propylpentanoate, 56cck4f86g, Valontin
Molecular Formula
C16H30CaO4
Molecular Weight
326.48  g/mol
InChI Key
PIZHURYFCSGTJX-UHFFFAOYSA-L
FDA UNII
56CCK4F86G

Valontin
A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
1 2D Structure

Valontin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
calcium;2-propylpentanoate
2.1.2 InChI
InChI=1S/2C8H16O2.Ca/c2*1-3-5-7(6-4-2)8(9)10;/h2*7H,3-6H2,1-2H3,(H,9,10);/q;;+2/p-2
2.1.3 InChI Key
PIZHURYFCSGTJX-UHFFFAOYSA-L
2.1.4 Canonical SMILES
CCCC(CCC)C(=O)[O-].CCCC(CCC)C(=O)[O-].[Ca+2]
2.2 Other Identifiers
2.2.1 UNII
56CCK4F86G
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2 Propylpentanoic Acid

2. 2-propylpentanoic Acid

3. Convulsofin

4. Depakene

5. Depakine

6. Depakote

7. Dipropyl Acetate

8. Divalproex

9. Divalproex Sodium

10. Ergenyl

11. Magnesium Valproate

12. Propylisopropylacetic Acid

13. Semisodium Valproate

14. Sodium Valproate

15. Valproate

16. Valproate Calcium

17. Valproate Sodium

18. Valproic Acid

19. Valproic Acid, Sodium Salt (2:1)

20. Vupral

2.3.2 Depositor-Supplied Synonyms

1. 33433-82-8

2. Valproic Acid Calcium Salt

3. Valproate Calcium

4. Calcium;2-propylpentanoate

5. 56cck4f86g

6. Valontin

7. Calcium 2-propylpentanoate

8. Calcium Dipropylacetate

9. Valproic Acid Hemi-calcium Salt

10. Calcium Bis(2-propylpentanoate)

11. Dipropylacetic Acid Calcium Salt

12. 2-propylpentanoic Acid Calcium Salt

13. Dipropylacetate De Calcium [french]

14. Dipropylacetate De Calcium

15. Einecs 251-521-7

16. Unii-56cck4f86g

17. Pentanoic Acid, 2-propyl-, Calcium Salt

18. 2-propylvaleric Acid Calcium Salt (2:1)

19. Ccris 8570

20. Convulsofin (tn)

21. Valeric Acid, 2-propyl-, Calcium Salt (2:1)

22. Schembl139237

23. Dtxsid5020237

24. Akos015915492

25. D08667

26. Valeric Acid, 2-propyl-, Calcium Salt

27. Q27261400

28. Pentanoic Acid, 2-propyl-, Calcium Salt (2:1)

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 326.48 g/mol
Molecular Formula C16H30CaO4
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count8
Exact Mass326.1770003 g/mol
Monoisotopic Mass326.1770003 g/mol
Topological Polar Surface Area80.3 Ų
Heavy Atom Count21
Formal Charge0
Complexity87.9
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anticonvulsants

Drugs used to prevent SEIZURES or reduce their severity. (See all compounds classified as Anticonvulsants.)


GABA Agents

Substances used for their pharmacological actions on GABAergic systems. GABAergic agents include agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function. (See all compounds classified as GABA Agents.)


Antimanic Agents

Agents that are used to treat bipolar disorders or mania associated with other affective disorders. (See all compounds classified as Antimanic Agents.)


Enzyme Inhibitors

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. (See all compounds classified as Enzyme Inhibitors.)


ABOUT THIS PAGE

Valontin Manufacturers

A Valontin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Valontin, including repackagers and relabelers. The FDA regulates Valontin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Valontin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Valontin Suppliers

A Valontin supplier is an individual or a company that provides Valontin active pharmaceutical ingredient (API) or Valontin finished formulations upon request. The Valontin suppliers may include Valontin API manufacturers, exporters, distributors and traders.

Valontin GMP

Valontin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Valontin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Valontin GMP manufacturer or Valontin GMP API supplier for your needs.

Valontin CoA

A Valontin CoA (Certificate of Analysis) is a formal document that attests to Valontin's compliance with Valontin specifications and serves as a tool for batch-level quality control.

Valontin CoA mostly includes findings from lab analyses of a specific batch. For each Valontin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Valontin may be tested according to a variety of international standards, such as European Pharmacopoeia (Valontin EP), Valontin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Valontin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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