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Chemistry

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Also known as: Fluocortin butyl ester, Vaspit, 41767-29-7, Sh k 203, Sh-k-203, 6n7oa9mo7o
Molecular Formula
C26H35FO5
Molecular Weight
446.6  g/mol
InChI Key
XWTIDFOGTCVGQB-FHIVUSPVSA-N
FDA UNII
6N7OA9MO7O

Fluocortin Butyl Ester
1 2D Structure

Fluocortin Butyl Ester

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
butyl 2-[(6S,8S,9S,10R,11S,13S,14S,16R,17S)-6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoacetate
2.1.2 InChI
InChI=1S/C26H35FO5/c1-5-6-9-32-24(31)23(30)21-14(2)10-17-16-12-19(27)18-11-15(28)7-8-25(18,3)22(16)20(29)13-26(17,21)4/h7-8,11,14,16-17,19-22,29H,5-6,9-10,12-13H2,1-4H3/t14-,16+,17+,19+,20+,21-,22-,25+,26+/m1/s1
2.1.3 InChI Key
XWTIDFOGTCVGQB-FHIVUSPVSA-N
2.1.4 Canonical SMILES
CCCCOC(=O)C(=O)C1C(CC2C1(CC(C3C2CC(C4=CC(=O)C=CC34C)F)O)C)C
2.1.5 Isomeric SMILES
CCCCOC(=O)C(=O)[C@H]1[C@@H](C[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2C[C@@H](C4=CC(=O)C=C[C@]34C)F)O)C)C
2.2 Other Identifiers
2.2.1 UNII
6N7OA9MO7O
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Fluocortin Butyl Ester

2. Fluocortinbutyl

3. Vaspit

2.3.2 Depositor-Supplied Synonyms

1. Fluocortin Butyl Ester

2. Vaspit

3. 41767-29-7

4. Sh K 203

5. Sh-k-203

6. 6n7oa9mo7o

7. Varlane

8. Shk-203

9. Butyl 2-[(6s,8s,9s,10r,11s,13s,14s,16r,17s)-6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoacetate

10. Fluocortin Butyl (usan)

11. Butyl 6alpha-fluoro-11beta-hydroxy-16alpha-methyl-3,20-dioxopregna-1,4-dien-21-oate

12. Fluocortin Butyl [usan]

13. Butyl6alpha-fluoro-11beta-hydroxy-16alpha-methyl-3,20-dioxopregna-1,4-dien-21-oate

14. Unii-6n7oa9mo7o

15. Fluocortinbutyl

16. Fluocortin Butyl [usan:ban]

17. Einecs 255-543-8

18. Schembl25218

19. Fluocortin Butyl [mi]

20. Chembl2105087

21. Dtxsid60194590

22. Fluocortin Butyl [mart.]

23. Chebi:135728

24. Fluocortin Butyl [who-dd]

25. Zinc4213352

26. 6-alpha-fluor-11-beta-hydroxy-16-alpha-methyl-3,20-dioxo-1,4-pregnadien-21-saure-butylester

27. Butyl 6-alpha-fluoro-11-beta-hydroxy-16-alpha-methyl-3,20-dioxo-1,4-pregnadien-21-oate

28. Hy-106567

29. Cs-0026066

30. D04217

31. Q27265191

32. Butyl 6.alpha.-fluoro-11.beta.-hydroxy-16.alpha.-methyl-3,20-dioxopregna-1,4-dien-21-oate

33. Pregna-1,4-dien-21-oic Acid, 6-fluoro-11-hydroxy-16-methyl-3,20-dioxo-, Butyl Ester (6.alpha.,11.beta.,16.alpha.)-

34. Pregna-1,4-dien-21-oic Acid, 6-fluoro-11-hydroxy-16-methyl-3,20-dioxo-, Butyl Ester (6alpha,11beta,16alpha)-

2.4 Create Date
2007-02-28
3 Chemical and Physical Properties
Molecular Weight 446.6 g/mol
Molecular Formula C26H35FO5
XLogP34.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass446.24685237 g/mol
Monoisotopic Mass446.24685237 g/mol
Topological Polar Surface Area80.7 Ų
Heavy Atom Count32
Formal Charge0
Complexity877
Isotope Atom Count0
Defined Atom Stereocenter Count9
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Dermatologic Agents

Drugs used to treat or prevent skin disorders or for the routine care of skin. (See all compounds classified as Dermatologic Agents.)


Glucocorticoids

A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system. (See all compounds classified as Glucocorticoids.)


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Looking for 41767-29-7 / Fluocortin Butyl Ester API manufacturers, exporters & distributors?

Fluocortin Butyl Ester manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Fluocortin Butyl Ester API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Fluocortin Butyl Ester manufacturer or Fluocortin Butyl Ester supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Fluocortin Butyl Ester manufacturer or Fluocortin Butyl Ester supplier.

PharmaCompass also assists you with knowing the Fluocortin Butyl Ester API Price utilized in the formulation of products. Fluocortin Butyl Ester API Price is not always fixed or binding as the Fluocortin Butyl Ester Price is obtained through a variety of data sources. The Fluocortin Butyl Ester Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Fluocortin Butyl Ester

Synonyms

Vaspit, 41767-29-7, Sh k 203, Sh-k-203, 6n7oa9mo7o, Varlane

Cas Number

41767-29-7

Unique Ingredient Identifier (UNII)

6N7OA9MO7O

Vaspit Manufacturers

A Vaspit manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Vaspit, including repackagers and relabelers. The FDA regulates Vaspit manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Vaspit API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Vaspit Suppliers

A Vaspit supplier is an individual or a company that provides Vaspit active pharmaceutical ingredient (API) or Vaspit finished formulations upon request. The Vaspit suppliers may include Vaspit API manufacturers, exporters, distributors and traders.

click here to find a list of Vaspit suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Vaspit USDMF

A Vaspit DMF (Drug Master File) is a document detailing the whole manufacturing process of Vaspit active pharmaceutical ingredient (API) in detail. Different forms of Vaspit DMFs exist exist since differing nations have different regulations, such as Vaspit USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Vaspit DMF submitted to regulatory agencies in the US is known as a USDMF. Vaspit USDMF includes data on Vaspit's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Vaspit USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Vaspit suppliers with USDMF on PharmaCompass.

Vaspit GMP

Vaspit Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Vaspit GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Vaspit GMP manufacturer or Vaspit GMP API supplier for your needs.

Vaspit CoA

A Vaspit CoA (Certificate of Analysis) is a formal document that attests to Vaspit's compliance with Vaspit specifications and serves as a tool for batch-level quality control.

Vaspit CoA mostly includes findings from lab analyses of a specific batch. For each Vaspit CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Vaspit may be tested according to a variety of international standards, such as European Pharmacopoeia (Vaspit EP), Vaspit JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Vaspit USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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