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Chemistry

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Also known as: 1213269-98-7, Epi-743, Alpha-tocotrienol quinone, Epi 743, Alpha tocotrienol quinone, .alpha.-tocotrienol quinone
Molecular Formula
C29H44O3
Molecular Weight
440.7  g/mol
InChI Key
LNOVHERIIMJMDG-XZXLULOTSA-N
FDA UNII
6O85FK9I0X

Vatiquinone
Vatiquinone has been investigated for the treatment and prevention of Retinopathy, Rett Syndrome, Genetic Disease, Noise-induced Hearing Loss, and Methylmalonic Aciduria and Homocystinuria,Cblc Type.
1 2D Structure

Vatiquinone

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-[(3R,6E,10E)-3-hydroxy-3,7,11,15-tetramethylhexadeca-6,10,14-trienyl]-3,5,6-trimethylcyclohexa-2,5-diene-1,4-dione
2.1.2 InChI
InChI=1S/C29H44O3/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8,32)19-17-26-25(7)27(30)23(5)24(6)28(26)31/h12,14,16,32H,9-11,13,15,17-19H2,1-8H3/b21-14+,22-16+/t29-/m1/s1
2.1.3 InChI Key
LNOVHERIIMJMDG-XZXLULOTSA-N
2.1.4 Canonical SMILES
CC1=C(C(=O)C(=C(C1=O)C)CCC(C)(CCC=C(C)CCC=C(C)CCC=C(C)C)O)C
2.1.5 Isomeric SMILES
CC1=C(C(=O)C(=C(C1=O)C)CC[C@@](C)(CC/C=C(\C)/CC/C=C(\C)/CCC=C(C)C)O)C
2.2 Other Identifiers
2.2.1 UNII
6O85FK9I0X
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Alpha-tocotrienol Quinone

2. Epi-743

2.3.2 Depositor-Supplied Synonyms

1. 1213269-98-7

2. Epi-743

3. Alpha-tocotrienol Quinone

4. Epi 743

5. Alpha Tocotrienol Quinone

6. .alpha.-tocotrienol Quinone

7. 6o85fk9i0x

8. 2,5-cyclohexadiene-1,4-dione, 2-((3r,6e,10e)-3-hydroxy-3,7,11,15-tetramethyl-6,10,14-hexadecatrien-1-yl)-3,5,6-trimethyl-

9. 2-((r,6e,10e)-3-hydroxy-3,7,11,15-tetramethylhexadeca-6,10,14-trien-1-yl)-3,5,6-trimethylcyclohexa-2,5-diene-1,4-dione

10. Vatiquinone [usan]

11. Vatiquinone [usan:inn]

12. Unii-6o85fk9i0x

13. Vatiquinone [inn]

14. Vatiquinone [jan]

15. Vatiquinone (jan/usan)

16. Schembl503125

17. (r)-alpha-tocotrienol Quinone

18. Chembl1812161

19. Schembl14639355

20. Dtxsid90153231

21. Bcp21072

22. Ex-a5566

23. Db11917

24. 2-[(3r,6e,10e)-3-hydroxy-3,7,11,15-tetramethylhexadeca-6,10,14-trienyl]-3,5,6-trimethylcyclohexa-2,5-diene-1,4-dione

25. Hy-16772

26. Cs-0012384

27. D10407

28. A937320

29. Q27265220

30. Epi 743;epi743; Vatiquinone; Alpha-tocotrienol Quinone

31. 2-((3r,6e,10e)-3-hydroxy-3,7,11,15-tetramethylhexadeca-6,10,14-trien-1-yl)-3,5,6-trimethylcyclohexa-2,5-diene-1,4-dione

32. 2-[(3r,6e,10e)-3-hydroxy-3,7,11,15-tetramethyl-6,10,14-hexadecatrien-1-yl]-3,5,6-trimethyl-2,5-cyclohexadiene-1,4-dion

2.4 Create Date
2010-07-06
3 Chemical and Physical Properties
Molecular Weight 440.7 g/mol
Molecular Formula C29H44O3
XLogP37.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count12
Exact Mass440.32904526 g/mol
Monoisotopic Mass440.32904526 g/mol
Topological Polar Surface Area54.4 Ų
Heavy Atom Count32
Formal Charge0
Complexity857
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count2
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Indication

Treatment of Leigh syndrome


Treatment of mitochondrial disease


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ABOUT THIS PAGE

Vatiquinone Manufacturers

A Vatiquinone manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Vatiquinone, including repackagers and relabelers. The FDA regulates Vatiquinone manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Vatiquinone API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Vatiquinone Suppliers

A Vatiquinone supplier is an individual or a company that provides Vatiquinone active pharmaceutical ingredient (API) or Vatiquinone finished formulations upon request. The Vatiquinone suppliers may include Vatiquinone API manufacturers, exporters, distributors and traders.

click here to find a list of Vatiquinone suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Vatiquinone USDMF

A Vatiquinone DMF (Drug Master File) is a document detailing the whole manufacturing process of Vatiquinone active pharmaceutical ingredient (API) in detail. Different forms of Vatiquinone DMFs exist exist since differing nations have different regulations, such as Vatiquinone USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Vatiquinone DMF submitted to regulatory agencies in the US is known as a USDMF. Vatiquinone USDMF includes data on Vatiquinone's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Vatiquinone USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Vatiquinone suppliers with USDMF on PharmaCompass.

Vatiquinone GMP

Vatiquinone Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Vatiquinone GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Vatiquinone GMP manufacturer or Vatiquinone GMP API supplier for your needs.

Vatiquinone CoA

A Vatiquinone CoA (Certificate of Analysis) is a formal document that attests to Vatiquinone's compliance with Vatiquinone specifications and serves as a tool for batch-level quality control.

Vatiquinone CoA mostly includes findings from lab analyses of a specific batch. For each Vatiquinone CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Vatiquinone may be tested according to a variety of international standards, such as European Pharmacopoeia (Vatiquinone EP), Vatiquinone JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Vatiquinone USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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